What state are you in?
Absolutely untrue? Do you have a study you would like to share?
Until we have a study showing otherwiseā¦
One could argue the reason why estrogen is less on T creams is because levels are declining so quickly that thereās not much time to convert T to E2 since levels are not as stable.
Thatās why you must apply creams so often, or else levels will decline very quickly.
The pharmacokinetics of testosterone cream applied to scrotal skin
Journal of Andrology March 2017
Read it and get back to meā¦
Keith Nichols, MD
Tier 1 Health and Wellness
2120 Northgate Park Lane
Chattanooga, TN 37415
931-520-0200
Case study: Absorption of testosterone cream via scrotal delivery
Pubmed30384643
Twice daily application provides a consistent serum level of free and total testosterone. There is not a 100ng/dL drop from one application to the next. My daily injections were nothing compared to this method.
Keith Nichols, MD
Tier 1 Health and Wellness
2120 Northgate Park Lane
Chattanooga, TN 37415
931-520-0200
1 Like
I think it works the other way buddy. Where is your study that proves your opinion ?
You cant state an opinion and then get a different perspective on it and tell that person they need proof because they believe your opinion to be untrue?? Wtf.
We can disagree with each other and actually disagree with studies too.
1 Like
I donāt use it twice a day that is why I am asking. My levels do drop towards the end of the day. My labs are always 9-10 hours after application.
Washington
Yah definitely take 2 at 6am and take 2 at 6pm. Honestly I might not even need to take the 2nd one until right before bed.
Ya there is no proof and yeti mentioned earlier heās comparing apples to oranges.I think system is still thinking cream and not thinking āapplying to scrotum with creamā. Because obviously cream itself applied to my stomach or whatever is shit.
I offered meta-analysis, multiple studies showing Intramuscular TRT is more effective than transdermal formulations at increasing LBM and improving muscle strength, I was met with āabsolutely untrueā even though thatās what the multiple studies found and instead I was given breadcrumbs to follow instead of the poster providing a link to a study proving that Intramuscular TRT is not more effective than transdermal formulations at increasing LBM and improving muscle strength .
Remember what we are talking about, we are talking about Intramuscular TRT is more effective than transdermal formulations at increasing LBM and improving muscle strength for which so far I have no proof stating otherwise.
The conversation started out from my previous post about Intramuscular TRT is more effective than transdermal formulations at increasing LBM and improving muscle strength, you went off on a tangent talking about ādaily injections were nothing compared to this methodā or that twice daily application provides a consistent serum level of free and total testosterone.
Weāre talking about Intramuscular TRT is more effective than transdermal formulations at increasing LBM and improving muscle strength, I was met with āabsolutely untrueā.
Do you or do you not have a study that shows Intramuscular TRT is NOT more effective than transdermal formulations at increasing LBM and improving muscle strength?
System
Did you read the studies?
This is not transdermal this is scrotul application.
The study says it.
Your comparing apples to smoothies.
Iāve linked to the same study 5 times. No way these are breadcrumbs and please tell me youāve read it. If you are not going to read the study then why debate the point.
Yeti is on point. Cream is so much better than injections. I think most men would love it.
Especially those who have issues with cypionate.
I am going to try it, but I will keep the second dose close to 5 hours before blood is drawn which is what is recommended. So will apply at 7:30AM as I have and reapply around 11:30AM. I donāt care where I am at one or two hours after application when I am peaking, I want to know closer to ātroughā readings. Cannot see myself doing it long term though as just applying daily is inconvenient to me so adding another application will drive me nuts.
1 Like
Thatās cool let us know how it goes. Iāll be looking forward to seeing the results. Iād the cream of high quality. Do you get a consistent dose from it?
I may eventually switch to cream too. But right now doing cream 2x a day is not appealing.
I wonder though which has more healthy impact on your health not just testosterone numbers.
Yes I have been consistent feeling so far. I did drop from previous levels once but was when I switched from a 10% cream to a 20% cream so that I did not have to use as many clicks. It could have been my absorption changed due to the different consistency of cream from the change in potency. I also question the quality of mixing on that particular tube though as it had some clumping that I have not had in others. I talked to the pharmacy about it and it shouldnāt happen again. Iāll see what happens with my next labs with my current tube but I feel good right now so not that worried about it.
1 Like
I do feel really good right now with the cream. The only issue I have with it is waiting for it to dry every morning before getting dressed. Going to twice a day just compounds on that. I donāt want to sit around in a stall at work for 5 min waiting for it to dry to pull up my pants so it doesnāt rub off on my underwear. Vacationing also is a little difficult for me as I donāt like having to think about going swimming or something and worrying about washing it off before I can get full absorption.
I may sound like I am trying to talk you out of a cream but Iām not lol. Just sharing my gripes so you have some things to think of that may affect you also.
I wish I knew if there were any other health benefits with cream vs injections. I do like the more consistent day to day variations of a cream (applied once daily) as it more closely relates to normal hormone fluctuations which I would think would be better for you though.
1 Like
That is untrue. look at the study you are referring to. There was no comparison using trans scrotal application. If there were the results would have been different.
1 Like
Correct but in science and medicine that is what we call an educated guess or an assumption without actual proof.
I am in no way suggesting creams are no good, in fact they are now gaining popularity and I look forward to seeing more studies on their effectiveness. I may try out creams for myself if injections proves unworthy after Iāve given it a solid chance.
I donāt know how they run these studies, but do they verify that they have comparable t levels before running the tests? I saw the baseline LBM and strength numbers and all but saw nothing stating what t-levels the participants had compared to each other. I would hope they would, but leaving that aspect out for me to assume just leaves me with doubt on the study. I hate these studies as they never have enough data for me to buy what they are selling. The same with the study others are using to say cream does not significantly impact estrogen levels. The study didnāt even use TRT protocols because they were testing absorption after initial application, not long term effects.