Anyone experience ED issues at around 6 ng/ml prolactin?

I’m on a trt protocol that i switched to 7 weeks ago and just had labs done. My last two labs have my prolactin at 6.5 (on a 10 week 24mg daily anvar +trt) cycle, and my regular TRT protocol. I do take a little AI which i know can suppress it, I also take Adderall which i know can also suppress it. Should i try up my prolactin to see if it prolongs erections? I’ve noticed a good erection only lasts 5-8 minutes now, where it used to be much longer… I’m a ~40 yr old fit bodybuilder type, that’s lean and eats/lives healthy with great blood pressure/cardio, so it should be better than this. I would appreciate tips!

My current protocol:
175mg/week test cyp - pinned EOD
110 units of HCG pinned EOD - tried to find a minimal effective unit to prevent ball shrinkage.
.125mg anastrazol EOD

I take adhd medication daily too. I noticed vyvanse (generic) lowers my nitric oxide levels (used test strips), but can be supplemented. Im taking Dexamphetamine now (30-40mg/day) adderral family of amphetamines. I know this lowers prolactin. I don’t know if the low prolactin is part of the issue for me.

Does anyone experiment with raising/lowering prolactin to test erection quality?
I’ll post my recent labs done yesterday, but the total/free test hasn’t come back yet. I’ll update the post when it does.
My previous labs after a short cycle of anavar (24mg/daily) had my prolactin at 6.5 - could post those as well. I had the same erection quality issue then, but vastly different lab results obviously. Nothing was out of range except total/free test which were pretty high.


Higher PRL isn’t associated with better erections or libido. I would focus on other factors in your case.

Vyvanse didn’t make my erections smaller, but it did cause my semen to come out at the thought of being with a women.

It’s not your prolactin level that’s causing your issues. More likely the ADHD meds or maybe the AI.

By the way, my prolactin is 6.4 last time I checked, no issues.

I do take a high dose of the ADHD med, and it can cause vaso constriction causing cold hands/feed etc. So maybe its slowing blood flow to extremities and causing issues there. I’ll try cut that out.
I’m more concerned if its the AI - I’ve tried every dose/pin frequency that offered the benefits of TRT and exhausted them all. I need AI - maybe i can cut that back a bit though?

I did get the rest of my labs. - Total T - 1182 ng/DL. Free T - 264.8 on the 35-155 pg/mL scale. estradiol is 41 pg/mL.
Could it be my TT/Estradiol ratio is off?

I’m not taking any DHEA supplements at the moment, but have a bottle from a while back - not sure if i’d need that or not…

I’ve been reading about the ideal Ratio for Total T to Estradiol, and my TT to e2 ratio is at 28.8. Should i lessen the ai or increase HCG dose and let my e2 climb towards the “ideal” 60-84 range to see if that works? Or is that not widely accepted as the ideal range anymore?

Since I’m at a low HCG dose and I’m pretty much cumming dust. practically nothing comes out.

Update - I increased my HCG to 150 units EOD from 100 units, and there was a noticeable bump in erection quality after a few days. Obviously, my hormones aren’t stabilized yet, but I think that tells me it’s hormonal and may be suboptimal test/e2 ratio related.

That bump in EQ was short lived, and brought a lot of cystic acne with it. I went back to 100 units of HCG EOD.