Any Reason E2 Would Increase on EOD Injections?

I did not have great libido but it was better than what I have today… it was not ideal and I wanted to get to a point where I felt ideal…

My goal is to avoid AI altogether. If lowering EOD dose doesn’t get me there then I will use AI

Im srs starting to believe that u WANT large fluctuations in T levels for optimal mood and libido. Thats how it works naturally, it spikes in the morning and at the end of the day it is some times 40-50% lower. I dont know where the fucking stupid idea of “keeping constant levels” came from but it is just that, stupid. Im very interested to try out that oral stuff actually.

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I agree, just thinking a short trial of it would give you your answer, sooner than later. Good luck. Looking forward to seeing what your solution is.

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Very good point. You probably would not be surprised at how many guys I see who get their levels checked by the PCP, mid 300s, then three months later they start with us and come back at 500, yet still feel like shit.

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I have no idea.

Eventually E will stabilize and probably dip, along with SHBG. I switched to daily shots 2 years ago, and it took a year to really see positive results with libido. Mine is nonstop and Im always wanting to bang but it took a whole year of consistency to allow things to be the norm. I have lowered my dose, but I also blast once a year, around spring time, and then chill the rest of the year. So labs will give you an idea of whats going on inside your body, but unfortunately your brain is also tied to this. So if you simply stay consistent, you should reach a point in which taking your medicine is second nature. Just cant expect your libido to jump up, like it does with amphetamines and other stimulants that work serotonin, and dopamine. TRT has to happen at a more natural pace which can take months to a year.

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Well then wouldn’t transdermals and something like jatenzo be the best practice? Both of those allow for big spikes daily.

Probably would. I really wanna try out that Jatenzo stuff, too bad we dont have it in my country.

You ever try the gels or cream?

Yes albeit a super low dose because welcome to fucking scandinavia, it gave me some libido actually, better than big injections, but ya the energy was pretty shitty, didnt resolve my other symptoms. Ive heard good stuff about cream on ur ballz tho

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I’m now 7 weeks into my EOD regimen with a lower dose (lowered by 10mg per injection) and my e2 is just as high…

T - 722
Free T - 29.7
E2 - 49.2 (7.6-42.6)

I think I’m going to try .125 anastrozole twice a week on Monday and Thursday mornings to see if I notice a difference and then I’ll know for sure that E2 is the issue which I’m suspecting it is.

Higher constant levels of T means possibly more conversion or high steady levels of E2 rather than higher peaks and lower troughs. Not sure why people think frequency lowers E2.

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Many lower the dose (mg/week) when they move to more frequent injections.

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That true I guess but it’s dishonest of people to think the frequency is what did the trick.

Yea I know everyone is different but for me frequency increased e2 did not decrease. I’m thinking of going back to 2x per week injections with .125 anastroozle 2x as well

Exactly, dependent upon our metabolism. The trough level could be higher with increased frequency, while the peak level is lower.

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Are you sure you’re not just seeing a higher trough because people who only inject once or twice a week wait a long time until injection day to do bloods, and nobody ever posts the mega skyrocket in e2 etc they get the day or two after injecting?

Any update from the OP?

This touches on a great point about the HUGE lack of peak readings in the trt world. People would probably be very surprised at how high their e2 levels get even on a twice a week schedule. I bet we’d get a lot more answers and information if we had guys comparing both peak and trough on their protocol.

Yep, but the same things just keep getting parroted over and over. I want to test my peaks as well to see the variance. Would explain why I’ve had my e2 in the 40’s on the sensitive test and had issues, because my peak may have been in the 50’s? 60’s? Who knows!

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