Anybody notice a bit of an uptick in anxiety and restlessness primarily on the sleep department with TRT?
I am on a low dose of 10mg daily shallow IM. It feels lately like I have a ton of restless energy. I have been slacking at going to the gym due to a move and start up again today. Is it possible that could be the culprit? Any advice is appreciated. Going to get labs drawn this week for sure.
yes, above 35mg daily. i highly doubt 10mg is the root cause of your issues, but i’m sure there could be exceptions. i recall watching some TRT doc saying that some men on T benefit from pregnenolone 100mg+magnesium when anxious on TRT. but again, at your dose, i give it a small chance. look for other causes, diet, Thyroid? i’ve been suffering anxiety for decades, although got it under control last 2 years, so i know a thing or 2
Yeah I am skeptical it’s the TRT either. I can’t really pin point the issue though as life is pretty great right now for me for the most part. I am going to get blood drawn today just to check it out and see if that coudl be a cause. Thank you !
TRT can deplete magnesium and many other vitamins and minerals, especially iron due to the creation of higher hemoglobin levels. In turn this can send some men’s ferritin levels into the floor.
I find TRT depletes my magnesium more than anything, and this has a side effect of dropping my vitamin D levels, because magnesium is required by the enzymes that help absorb and convert vitamin D to its active form in the liver.
This decrease in vitamin D due to the magnesium problem, would also hinder my iron absorption. It’s a domino effect.
I’m so much calmer after 12 days on 600 mg magnesium glycinate! It was only 10 days after starting magnesium supplementation that my vitamin D level started rising above 30.
Twelve days ago, I discovered a magnesium deficiency. I require 600 mg of magnesium with my activity levels while on TRT. If you’re on vitamin D, supplementation, you requirements for magnesium goes up even higher.
Don’t forget to add vitamin K to your vitamin D supplementation.
I used to be on 7 mg daily cypionate injection protocols that crushed my ferritin levels due to the constantly elevated hormones. It was the main reason why I started iron supplementation, which I no longer require on oral testosterone due to the PK profiles.
It took me years to figure out what was causing my symptoms, a lack of iron due to these daily injection protocols. I finally gave up on injections and went on Jatenzo, no longer needing iron supplements.
I’ve been off iron supplements for 8 weeks and I’ve never felt better!
cool! yeah I do 5k vit D + k2. i do use doctors best mag glycine 200mg/night and some brand of magnesium malate powder, 200mg (elemental, not weight) in the AM. 400 total seems to work, but i might try going higher. recall seeing DeLauer saying he takes 1000mg/day
So my magnesium is normal . I had a Magnesium RBC test done to be sure. I also take nightly epsom salt baths and it really helps calm the muscles down. I used to supplement with Mag Glycinate but didn’t do a heck of a lot for me as I wasn’t deficient ( likely from the epsom salts )
I agree, but i get side effects from more magnesium. Im pretty happy with my mag levels, they are on the higher side of normal. RBC magnesium is fairly accurate within reason.
Im down to 10mg a day. I don’t think it’s my dose. I am wondering about adding Pregnenolone to the mix in a small dose at night. I think it’s possible that it may have dropped significantly since i don’t use HCG or anything to help with the other neuro hormones.
Hey Hinch, I’ll tell you what I figured out on my end. Even if your dosage is correct (sometimes its too high and will cause this) however… Exogynous Test is almost like a stimulant to your sympathetic nervous system. This is why your resting HR goes up almost immediately on starting TRT. If you are sensitive to caffeine in any way, either lower or cut out the caffeine. I always loved an afternoon cup of black coffee or if I was working out later in the day i never had any problem taking a scoop of PWO at 5pm. But on test, I was wide awake, jittery and anxious at midnight. I cut out caffeine after 12 noon and if I worked out later in the day I took a non-stim PWO. Things seems to fix themselves. Do this first and if it doesnt fix it, you may need to lower your dose. The half-life of caffeine is 8hours, so a 4pm dose of caffeine is the same as a half-dose at midnight. Your body may not have given a shit prior to T, but it is now extremely sensitive to it.
Also Rallee, dont just take pregnenolone without seeing if your body isn’t producing enough. Pregnenolone is “early” in the hormone cascade when your body is turning cholesterol into testosterone. Excess pregnenolone could just be turned into Estrogen. I would suggest DHEA at bedtime, its also a neurosteroid and buffers your cortisol. You would also probably benefit from CBD gummies. I get CBD/Melatonin/5HTP gummies from Redeem Therapeutics.
Nope i found the cause to all my symptoms. My iron was in the 10th percentile. Very bad, especially after a recent blood donation. Since supplementing , feeling like i did when i first started TRT again. Was a random one too, doc was like “ lets check iron for the hell of it “