3 Months In, Sky-High TT and E2

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Preferred Blasts on TRT?

Good everyday “TRT” dosing with 180 mg/week TC (1 injection every week, median PK parameters assumed) and trough sqeaking by at 1130 ng/dl if I spot reference range up to 1200 ng/dl. LMAO! But these dudes only see the trough data point. Remember the AUC for all the time prior to the trough data point. [image]

Preferred Blasts on TRT?

80 mg/week of TC to your point: [image] How many dudes you think are peaking at over 1145 ng/dl every day. 500 ng/dl trough with once weekly injection gives same AUC as every day injections that give roughly 820 ng/dl day in and day out (again, I’ve assumed mean PK parameters based on literature surveys of men on TC). But no, 80 mg/week is way low. 200 mg/week to resolve symptoms . We waged this war previously so let me avoid being vague. If you need 200 mg/week TC (again a…

See above two plots. With hindsight we now know you have a very expected pharmacokinetic response to injectable exogeous testosterone. How about 70 or 80 mg/week, measure trough in 5 weeks and reassess protocol in 12 weeks. If you aren’t carrying a lot of bodyfat you probably don’t need the AI. Monitor your BP and RHR.