Guys, for those of you who have seen me post this a few times before, I apologize.
I am posting this for those of you who have not seen it. It is queued up to the relevant part.
Once you understand that estrogen is a paracrine hormone, the notion of taking an AI becomes absolutely crazy:
I keep hearing these assertions. But nobody is offering anything to back them up. Look, if anastrozole is harmful, even at the low dose I’m on, I’d like to know. But nobody is showing me anything regarding the long term danger of anastrozole at low trt doses.
If it’s really as cut and dry as you guys are claiming, where’s the studies? Where’s the evidence that taking anastrozole at doses that don’t crash E2, is harmful long term?
@Gossamer by any chance did you watch this video clip? If you did, can you understand that any amount of an AI will lower estrogen but you have no idea WHERE it will be blocked due to it being a paracrine hormone?
@dbossa I wasn’t sure if you were answering my question or responding to Gossamer. Are you recommending that I increase my dose to see if it helps with ED?
Yes, the one that I discussed personal experience was directed at you. Was just curious if you have ever tried higher.
I listened to him twice, but didn’t really understand what he was saying. Then when you explained it, I went back and listened again, I understand what he’s saying, but I really don’t know what it means.
As I said before, I was reluctant to try an AI because I couldn’t find any long term studies on it with trt. So, I’m willing to try without it, but, and it’s a big but, I was such a bitch, and very emotional, a complete mess, when I wasn’t taking an AI, or even when I wasn’t dialed in and wasn’t taking enough of an AI dose. So, I do not want to go through that, nor put my wife through it again. If you say that it can take weeks or even months being off of anastrozole, before my body adjusts, I cannot go through that for weeks or months. It was the worst feeling of my life. Even worse than the way I felt with my T level at 170, pre trt.
If you went cold turkey, then absolutely yes. If you go by the way I suggested to you by email, not so much.
Ok. I appreciate your patience with me in this. Knowing my current protocol. 160mg test split into two doses, every 3.5 days, and 1/4 mg anastrozole @24 hrs post each injection, and knowing how my body will react without an AI, what would you suggest that I should try as a protocol?
I do appreciate the time you’re taking with me on this, and please note that my caution and skepticism aren’t a knock on you. It’s the way I approach these kinds of things.
This is what I sent you via email:
You’re doing the exact protocol I did for two years. Even the same day and same time of day!
IF you are anything like me you may be sensitive to the ups and downs of twice weekly injections. I felt like it was too much all at once and then nothing for a few days. I first started by moving to EOD injections and I felt better. As much as I hated injecting, I then tried daily to see if it made any difference, and it did. This kept my levels stable and no more ups and downs at all.
The other thing is my free T was in the teens during that time. Those levels were insufficient. In contrast, they are now well over 40. I switched doctors and convinced the new one to allow me to go higher. Guess what? I started feeling much better.
The next step was to get off the AI. Every other time I tried to I would immediately feel those “high E2 symptoms” creeping up. Some guys can stop cold turkey but I was not one of those guys. I was down to 1/4 tablet twice a week. I then started doing 1/4 tablet every 4 days… then every 5 days… then ever 6 days… then every 7… I forget at what point I stopped but there was a point that I just forgot to take it (because there was no indication that I needed it). Libido started to drastically improve and erections were harder and more consistent than before… not to mention, they lasted much longer. About a month later I remember feeling like I was breathing better, which was interesting.
The interesting thing is the higher I go the better I feel. I feel the main reason most guys need Ais is that their docs aren’t getting their levels high enough or they are sensitive to the once weekly or twice weekly injections.
I understand you are feeling great. My hunch is with a bit of experimenting, you could be feeling even better, and be healthier.
I have NO IDEA where your free T sits right now or if you ever tried higher or lower doses and what was the outcome.
This is something you could try as an experiment. Say you’ve been doing this 6 years and it is working for you. If anything starts to go horribly wrong you just fall back on your baseline protocol and there is no issue.
I know I can come across as aggressive in these forums, I just HATE misinformation. It’s the same misinformation that made me feel like crap for years and I’m trying to prevent others from going through what I went through. What I can say is that the higher my levels get the better my mood gets and I’ve got a ton of guys reporting the exact same thing. Some do have their limits though and they’re able to find those limits. In my case, when I did daily shots at a much higher dose I felt off but now that I’m doing IM 3 times a week I feel better than ever. All of these little experiments that I can then report to others.
Anyway, hope this helps!
I would personally bring up the dose to 200mg a week, do as frequent injections as you can, and wean off the AI slowly as I suggested. If things go wrong just go back to what you were doing. Either way, report back with your findings if you do.
Ok. How does this sound:
Take the 400mg for 14 days, divide that by 7, and that will be what I inject EOD?
Is that a good starting point?
What about anastrozole? Is there a way to keep that consistent while weaning off? The reason I ask, is because with my current protocol, I feel very consistent all week. I don’t notice any ups and downs, on one day compared to another.
High doses are always going to be what they study. Its not like theyre going to Study diluted micro doses for trt. Btw .5mg is a LARGE dose even per week it will cause problems.
Just curious did you do blood work on your eod protocol to see what your levels were doing day to day?
Yes the doses you are talking about will cause problems. The common doses recycled around forums .5 .25 .125 … etc etc are FAR from small doses. And it will fuck you up at thoses doses.
Danny, I have learnt tons from your good work, from the videos, from the posts and you have no idea how appreciative I am of this. I am doing well, in no small part, thanks to you. I state this so you understand the below is not bashing you, but meant to be constructive.
You statement doesn’t make sense to me. If you disagree with a point, by keeping quiet, how must one separate the bullshit from the cutting edge? I understand not wanting to put these people on the spot, but many viewers take everything as facts, and then the silence from you after affirms this.
Just because they decline a follow up debate, doesn’t mean there is no case for a constructive rebuttal from you or your team. You need to perhaps make follow up videos or even post comments with what you disagree with and why. It will only help matters.
@tfan866 I completely agree with you. It something we are trying to figure out. How do we ‘politely’ challenge a guest the very first time they are on and not make it so that nobody wants to come on.
I’m working on it. This interviewer stuff is new to me. I’m an IT guy and business owner for crissakes. I don’t even know how I got here!
@Gossamer need to drive my kids to school… I will reply shortly.
Same for me. If I cut the AI I get bitchy. When I take it, I turn into Professor Hulk from End Game. Real chill, nothing bothers me and I get stuff done. Keep in mind this is me breaking a half of a pill in half .25. If I were to take 1mg a week My e2 would crash so hard I wouldn’t be very fun to be around. I take that .25 24hours after my injection.
@In_Crom_We_Trust can I make the assumption that you’re doing weekly injections? How much?
Just curious. I started having nipple sensitivity and then a lump, which I understand is a precursor to gyno. I started an AI in order to stop this. Are you saying I don’t need the AI? I am not sure how to correct things. I was doing 200mg bi-weekly and dropped to 140 mg daily to see how that works.
They must learn this in school because those are nearly the exact words one of my old endo’s used.
