[quote]Bill Roberts wrote:
[quote]jMill2 wrote:
As for how many 2 weekers I plan to run before taking 4-6 off, probably 3. If you read through the second link I posted in the OP, I think Bill talks about how much “on” time per year is “safe”. I think he said between 1/3-1/2 of the year spent “on” is within “safe” range with the latter pushing it a little.
So, my cycle will probably look like this:
2 ON
2 off
2 ON
2 off
2 ON
4-6 off
I think of it kind of like one 14-16 week cycle. From reading what people who have run the 2-on/2-off have to report, it sounds like gains typically continue during the “off” weeks (or at least you maintain what you gained). If I had to guess, I’m thinking it might have something to do with the excess glycogen that is still hanging around during those 2 “off” weeks. If that’s true, then that is yet another of the numerous advantages I see with the protocol.[/quote]
I’m pretty convinced that the above-normal glycogen storage is gone within a matter of days of androgen levels returning to normal, given the pattern of rapid weight loss that is not fat or muscle loss and which is completed in that time-frame.
I expect that strength increases off-cycle are due to biological effects often being delayed relative to receptor activation. For example, suppose that under the influence of high androgen levels, a satellite cell fuses with a mature muscle cell, thus increasing its number of nuclei. This will result in ongoing higher capacity for protein synthesis, but the muscle wouldn’t have the full benefit or anything like it on the first day of this occurring. It might take quite a while.
It also may take the body time to learn to use the increased capacity of the muscle for strength. Even though it might be the case that the same nerve impulses will now produce a more forceful contraction, initially one might not have the same nerve impulses activating the muscle, as protective mechanisms may cause the higher weight to seem heavier than can be lifted.
My experience and that of anyone I’ve asked what they thought on it is that as one gets stronger, it is not that weights feel say half as heavy on getting twice as strong. No, a much heavier weight still feels much heavier: it’s just that now you can lift it despite it feeling much heavier. But I would suppose that if somehow, magically, that example doubling of strength happened overnight, for quite some time your body would not let you do it as it felt impossibly heavy.
The same thing might be the case, though of course at much smaller percentages, with the increased capacity for strength generated in the “on” weeks. Perhaps not everything that is in fact there at that point is yet utilizable, but in the following weeks the body learns to employ it.
[/quote]
Very well put per the man behind the strategy.
Awesome.