Yarmish's TRT Log

Continued…

Estradiol, Sensitive [Final]
Estradiol, Sensitive 38.4 H pg/mL 8.0-35.0 02 F
This test was developed and its performance characteristics
determined by LabCorp. It has not been cleared by the Food and
Drug Administration.
Methodology: Liquid chromatography tandem mass spectrometry(LC/MS/MS)
Notes
Flag Legend: Flag Legend: L (Below Low Normal) H (Above High Normal) LL (Alert Low) HH (Alert High) < (Panic Low) > (Panic High) A (Abnormal) AA (Critical Abnormal)
Collect Date & Time Date of Service
4/3/2019 9:19 am 4/3/2019 12:00 am FINAL
Status Signed
B0088272013
Req. Number
DAMARIS
Status Change Date 04/08/2019
Diagnostic Test / Results Results Out of Range Flag Units Range Site Stat
Triiodothyronine (T3), Free [Final]
Triiodothyronine (T3), Free 3.4 pg/mL 2.0-4.4 01 F
Sex Horm Binding Glob, Serum [Final]
Sex Horm Binding Glob, Serum 91.2 H nmol/L 16.5-55.9 01 F
Cardiovascular Report

So my DHEA is still only mid range and I have read that a 400-500 is optimal. I supplement with one DHEA pill a day would it be a good idea to start taking 2 at 1 in the morning and 1 at night?

My Hematocrit has also risen to 49.1% so I will be planning a donation soon.

All in all still am feeling good and energy is steady, They have me trying to eat more carbs as I am fairly restricted on them to hopefully bring SHBG down some as it has risen to 92 an all time high.

Thanks!

You are only changing the prescription and not actual dosing right? The way you worded it, it sounds like you would change injection also, but the plan says for prescription purposes only. Which I am guessing was for the new law you spoke of. From what I saw in your labs you actually have room to inject less as you are above range for both total and free T unless I missed something.

I am going form a .40 Twice a week to a .45 twice a week so from 160 to 180. She did word it a bit different there

Why is she increasing you though? Did I miss something or reading your labs wrong? You don’t even know what your total is because you are higher than the test even shows and 6 points higher than the range on free test. I see you SHGB is really high but again your free t and estrogen are both over the range so that isn’t an issue right now. And you stated you are feeling good so I’m confused on the need to increase.

I believe it is being raised in an effort to get my SHBG to come down, as Androgens will lower it. My next blood work I assume it will be lowered if the SHBG has no change. They also upped my Boron from 3mg to 6mg.

Still feeling good with this Protocol, Getting my first blood donation done on Thursday to get my hermatocrit down a few points.

So since I have lived in Europe the Pre blood draw form says that I am not eligible to Donate blood in the U.S. My Hematocrit was up to 49.1 as of my last Blood test and I know once you get over 51 that Defy will not help me until I get that number down.

I can’t believe that I can’t donate because I lived in Germany. Crazy to me

What other options do I have?

You can have a theraputic phlebotomy done. They just throw away the blood. You’ll need a doctor to give you a prescription for it. I’d talk to Defy and see what they recommend and if they can help. It might not be worth worrying about until you’re at the 51% threshold.

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Thank you , I will call my Dr tomorrow and see if I can get a therapeutic phlebotomy done as my blood pressure has risen to 140/70 the woman at the donation center said. She said it’s border line high and I’ve always had low blood pressure.

Some research shows I should take
More fish oil
COQ10
Grapefruit extract "But I have read there are side effects with this one "

Maybe a baby aspirin each day as well but ask you doctor about that.

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So I was able to get a Therapeuitic blood draw at the hospital blood bank today, I will check my blood pressure a bit later on but it may be placebo I do feel much better. She said that my Hemoglobin/iron was high and my blood pressure was still 140/70.

I will be having my bloods from defy in the next 3-4 weeks so I can see where my hematocrit is then, I am going to recommend lowering my dose to figure out why it has risen so much.

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So I had my 3-month bloods and will have a consult tomorrow.
Some Issues I have been having are low Libido and loss in Penile sensitivity along with more sweating than I have ever done and high blood pressure. I am assuming its High Estrogen which has gone up 12 points since my last blood test.

CBC With Differential/Platelet [Final]
Notes Fasting - Yes
WBC x10E3/u 3.4-10.8
L
7.1 01 F
RBC x10E6/u 4.14-5.80
L
5.41 01 F
Hemoglobin 16.8 g/dL 13.0-17.7 01 F
Hematocrit 49.3 % 37.5-51.0 01 F
MCV 91 fL 79-97 01 F
MCH 31.1 pg 26.6-33.0 01 F
MCHC 34.1 g/dL 31.5-35.7 01 F
RDW 12.9 % 12.3-15.4 01 F
Platelets x10E3/u 150-450
L
213 01 F
Neutrophils 47 % Not Estab. 01 F
Lymphs 43 % Not Estab. 01 F
Monocytes 9 % Not Estab. 01 F
Eos 1 % Not Estab. 01 F
Basos 0 % Not Estab. 01 F
Immature Cells NP 01 X
Neutrophils (Absolute) x10E3/u 1.4-7.0
L
3.3 01 F
Lymphs (Absolute) x10E3/u 0.7-3.1
L
3.0 01 F
Monocytes(Absolute) x10E3/u 0.1-0.9
L
0.6 01 F
Eos (Absolute) x10E3/u 0.0-0.4
L
0.1 01 F
Baso (Absolute) x10E3/u 0.0-0.2
L
0.0 01 F
Immature Granulocytes 0 % Not Estab. 01 F
Immature Grans (Abs) x10E3/u 0.0-0.1
L
0.0 01 F
NRBC NP 01 X
Hematology Comments: NP 01 X
Testosterone,Free and Total [Final]
Testosterone, Serum >1500 H ng/dL 264-916 01 F
Adult male reference interval is based on a population of
healthy nonobese males (BMI <30) between 19 and 39 years old.
Travison, et.al. JCEM 2017,102;1161-1173. PMID: 28324103.
Notes
Free Testosterone(Direct) 26.9 H pg/mL 8.7-25.1 01 F
Thyroxine (T4) Free, Direct, S [Final]
T4,Free(Direct) 0.93 ng/dL 0.82-1.77 01 F
TSH [Final]
TSH 0.388 L uIU/mL 0.450-4.500 01 F
Estradiol, Sensitive [Final]
Estradiol, Sensitive 47.1 H pg/mL 8.0-35.0

The 140 is not actually that important, the lower bottom number is 70. You do not have high blood pressure. It’s not even “borderline”. Relax. Do a little cardio. You’ll do more damage stressing about it than it could possibly do.

Thank you , It had just risen from 110 for no reason is why I was worried. Seeing my bloodwork I am going to say it’s high estrogen at fault?

As far as cardio I run 25-30 Miles per week and do strength training 4 days a week so i don’t think that’s the issue.

So I have some questions if you guys could kindly help me out…
My Test dose was raised from 160 a week to 180 and my 3 month bloods show that my Free T is down a good amount and my estrogen has risen. My SHBG has stayed pretty close and I am also having some Mild ED and loss of Libido along with sweating more than I have ever while exercising and just in general. I have a consult today do you think I should lower my dose back down and try to get my Estrogen lower which would also raise back up my free T?

You increased the dose and feel worse. I would say yes to lowering it and feeling better.

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So basically the extra Test converted to estrogen and lowered my free T in the process?

Thanks

Lower dose ED or EOD. That’s what I see on this forum.

No, that’s a ton of cardio. So, it may be estrogen at fault but I doubt it. It’s probably a deficiency in one of your minerals. At least a few of us have deficiency issues on TRT, especially when combined with working out. I get exercise induced hypocalcemia and that shoots up my BP. Some guys are anemic on TRT, some guys need copper, some guys need magnesium and some need zinc. I’m taking all of them on a weekly schedule now, and the calcium if 30 mins before I go to the gym (there’s a study showing that with hypocalcemia it only helps if you take the calcium at least 30 mins pre-workout - taking it after was of no benefit). You might have actually been borderlind deficient before and just not known it.

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The only item I am not taking is calcium maybe I will add that Thank you .

My consult with Defy he has my going to EOD with injections and taking my HCG 3 times a week, also lowering my dose to 160 as opposed to 180 and see how I feel. He suggested and anti-E but I am going to find a dose/protocol where I do not need that. I am also going to give Sub-Q try since I will be injecting more so hopefully this helps things.

I ordered some DIM to try for getting my E down in the mean time, anybody had good luck with it?