Hi been on Trt at 100mg per week with EOD injections in delts for 4 months now.
Was feeling really good but recently been feeling very lethargic and fatigued.
Also my levels went up on same dose and protocol after 3 months bloods ?
Thinking possibly I might need an Ai ?
Total t - 937
Estrogen - 60
Shbg - 22
All liver and other bloods are in range Hemocrit is fine …
No new stress just want to be back to normal …
@blshaw Hi ,sorry to trouble you, but would appreciate to hear your view on this ?
Hmm I would have expected the opposite as some lose this “feel good” period when natural production ceases but…
This speaks to that not happening.
What was the range on that E2 just to clarify? Ultra sensitive?
@blshaw it wasn’t a ultra sensitive I’ve struggle to locate a place that does in the Uk.
Our ref range ?
173.0]; Above high reference limit
TRT can suppress ferritin in some individuals making iron supplementation a must. Also, TRT cause cause you to burn through other vitamins and minerals, especially if your diet is lacking nutrients.
The estrogen can cause fatigue, low libido and erectile problems is some men. Arimidex, anastrozole at micro doses of 0.050-.125 is recommended if reducing the dosage and or injection frequency fails to resolves symptoms.
Please clarify, 100 mg of what ester?
Hi thanks for the reply, my diet is pretty good but I do supplement with vitamins but not iron…
This is from last bloods …
Serum folate level 13.6 ug/L [2.5 - 9999.0]
Serum vitamin B12 level 331 ng/L [120.0 -
900.0]; Adequate B12 stores.If the patient is on IM B12
therapy, it is not necessary to monitor B12 levels
Serum ferritin level 39 ng/mL [15.0 -
300.0]; Ferritin >15 and <100ng/mL. With low Hb and MCV,
a normal ferritin in the presence of inflammatory
changes does not exclude iron deficiency.
Ester is test E
I don’t have libido issues but have been a bit more emotional than normal …
This is part your problem, take it from someone who’s had personal experienced with iron deficiency on TRT. You need iron supplements.
Iron Chelate 25-50 mg and retest in 2-3 months.
That definitely points to excess estrogen.
Thanks I’ll get some iron for sure then ! Is my level low then ? What brand do you use
Would you recommend still trying and Ai low dose ? The tabs come in 1mg not sure how you could accurately dose that small of an amount …
I don’t know much about iron deficiency and would defer to @systemlord for experience. If that doesn’t help you I don’t feel you would be wrong to try microdosing an AI.
@blshaw ok nice one. Do people normally stay on an Ai once on ? Don’t want to be going up and down seems hard to stablize everything…
No, a lot of men eventually come off AI’s and lower their TRT dosing. Some guys on AI’s long term find undetectable estrogen values due to long term suppression, which can demineralize your bones.
AI’s can mess with your lipids, and decreases those fatty free esters needed for maintaining a healthy cardiovascular system.
That’s why I recommended the micro dosing AI’s, to minimize the side effects.
Whether you’re blocking aromatase or 5-alpha reductase, there are risks of affecting multiple hormonal pathways.
There’s no risk in reducing your TRT dosing.
I would, a very small dose after each injection. Then I’d try and assess why my e2 ratio was higher than normal. If it’s something I could fix, I would try. Would also consider adding CDG in.
How do you guys micro dose our tablets come in 1mg !?
What’s Cdg ?
Compounding pharmacies offer micro doses for anastrozole. A better route would be daily Cialis, which changes T:E2 ratios over several months. Cialis, ED drugs, is shown to decrease risk of heart attacks, even increase blood flow to the brain and also may decrease your risk of developing dementia.
So there’s more reason to take ED drugs than solely for erectile function.
Thanks I’ll look into that ! Very helpful much appreciated 
I’ve ordered some iron tabs also.
my iron level is low then ?
No, ferritin, iron can change drastically after eating something with iron in it.
@systemlord
Ok but I need to supplement with iron to bring Ferrartin in range?
Yes.