And this is on e7d injections? Test e or c?
Hahahaha!!
My partner is Steven Devos, also known as The Lifting Dermatologist, in Belgium. He started the YouTube channel and I partnered up with him over the summer so we are now co-owners of the channel and Facebook group.
I’m happily married to a beautiful woman who you’ve also seen a few times in my videos. We are working on having her interview Dr Fionulla McHale on women’s HRT.
The guy who wanted to see me with my shirt off literally just emailed me. I’m in bed with a cold but promised him I’ll take one over the weekend and send it to him.
I can’t even with this thread
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That’s your own damn fault for living in 
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You might be one of those guys that doesn’t respond to TRT with hormones levels that are consistent, some guys need the bigger fluctuations to more closely match that natural daily fluctuation to feel good on TRT.
So if injections fail you, try the T scrotal cream.
Dr. Saya did mention using a scrotal cream to increase my DHT, is this what you meant?
As for needing bigger fluctuations – are there any people on this community that found this to be true? I’d like to look into this.
I also used to use an AI and it helped me temporarily feel great, then after a while I felt my e2 crashed. However, back then I felt good some days of the week every week… the past few months on dailies have been almost completely negative. I’m only sticking through in the hope it ends up working out.
LOLOLOL. This is so entertaining! Although I feel bad being entertained at the expense of others…oh well haha.
Testosterone scrotal cream as in TRT. There have been guys who just don’t feel good on injections but feel good on tropicals.
There are dozens, in fact there is a guy over on Excelmale saying he felt blah on injections, but cream really work well. He had poor libido and bad erections and the cream fixed everything.
I’m saying if injections never works out, go scrotal cream.
You do need to watch lipids and BP though. I assume you’re healthy (lifestyle and exercise), thus you’ll probably be fine… BUT, if you were say, a morbidly obese, sedentary, type 2 diabetic, hypertensive male… shooting for a FT of 40 could spell disaster
I think he’s kidding, don’t actually send shirtless pics to guys online… unless you’re fully comfortable with any potential repercussion sending such a photo could have down the line
Saying that there is no evidence that it’s causing harm is unfortunately the wrong approach when it comes to the safety assessment of drugs.
It’s the safety that needs to be demonstrated and not the lack of harm.
And unfortunately at the moment there is insufficient data available that unequivocally demonstrates the safety of TRT in physiological doses - there just is residual uncertainty. Supraphysiological doses haven’t been addressed at all until now with well designed an adequately powered long term studies.
You can be smoking two packs of cigarettes a day and it won’t show any negative effects up to 10 or even 20 years. No increased risk for lung cancer or developing COPD in the first 10 years, so with your logic you would be recommending to smoke because of the lacking evidence of harm.
I don’t think that TRT is comparable with regards to the harm it can induce to the cigarette example but I hope you get the point.
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Correct. Enanthate.
Sadly my FT is just barely mid-range despite TT being around 1100 and shbg being below the range low… I can’t up my dosage either because of sleep problems on TRT. Instead i actually had to lower my dose.
And i have not heard anyone come up with a scientific explanation to this other than saying “Everybody is different”.
@johann77 trust me when I say I totally understand your point of you and, using that perspective, you are correct.
My perspective is this:
We have been studying testosterone for over 80 years. If it had any potential to cause harm would we have not seen it by now? We know that synthetic derivatives cause harm but there is no evidence for testosterone doing the same.
I would love to report back to the world after seeing some blood work that testosterone somehow caused some harm in me so I can warn others if this actually happened.
I find it difficult to make decisions on things based on a lack of evidence for any given position. It’s like saying I’m not going to spend my time worrying about ever being attacked by a unicorn because there is no evidence that unicorns exist. Your position is unicorns ‘might’ exist so we should be careful. When someone can demonstrate a unicorn, I’ll keep it in mind. Until that time, not so much.
@unreal24278 again, we’re not ‘shooting’ for any given number.
I don’t believe it is the testosterone itself that would cause an issue in a ‘morbidly obese, sedentary…’ guy. It is oftentimes the sudden increase in physical activity due to the energy/wellbeing that the guy will experience, when his body simply isn’t ready for it, and boom!
I’d be willing to wager that you give him a free T of 40, in your example, but let him sit there and not do any new physical activity and he would most likely be fine.
It’s late here (where I live)… but I should specify we have a weak body of evidence suggesting testosterone itself has the potential to induce harm at about a rate similar to (but less so) than numerous synthetic derivitaves, many a times through similar mechanisms
There are numerous mechanisms as to why a sedentary, morbidly obese, type 2 diabetic, hypertensive male could stroke out/have a myocardial infarction from high dose test
- sympathetic nervous system stimulation (increased catecholmaine reuptake/ upregulation of Veda adrenergic receptors)
- increased BP (RAAS modification/water retention)
- lipid strain (higher dosages cut HDL down by about 20-30%) for someone in his stage, this makes a HUGE difference over the years
- endothelial dysfunction (yes, supra doses of test induce this about as reliably as many synthetic derivitaves)
- cardiac enlargement (I’d hypothesise testosterone actually has a higher predispensity to do this comparative to many synthetic DHT derivitaves. The heart of such an individual specified above is likely already significantly diseased/enlarged. I wouldn’t give someone with cardiomyopathy associated with deteriorating cardiac function the go ahead to cycle)
- induction of a hypercoaguable state (can link literature to demonstrate this happens).
This isn’t TRT I’m talking about, this is like giving them 400mg/wk or something. A dose such as 200mg weekly is a very different story. This also assumes the individual makes no stride to change his habits/behavior, still eats fast food 24/7 etc
I don’t mean to be a dick/arguementative so I apologise if I come across as this. I just wanted to specify I do believe there is a demographic in which giving supraphysiologic doses of test could prove to be quite dangerous.
Blood work isn’t the be all end all. Echocardiogram are incredibly important to gauge health whilst on AAS. Though only a select few (or those who abuse extensively, like grams upon grams weekly) appear to develop cardiomyopathy. It appears subclinical cardiac dysfunction develops… eventually… after like 10-20 years of continual use (as in 10 years spent ON) at very high dosages does this occur. However this differs for everyone, some will develop deleterious morphological alterations within the myocardium after a single cycle
Also, echocardiogram doesn’t measure damage incurred on a cellular level
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You’re the furthest thing from a dick in this forum. I didn’t take that as being argumentative whatsoever. It was very well said.
I just wish the evidence was stronger considering the amount of time we’ve been studying it. It leaves a lot of this stuff up to interpretation.
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You’re right, there’s very little literature/evidence garnering the harms of testosterone or even synthetic derivitaves but we do know this
- there is a supposed correlation between high dosage use and sudden cardiac death, whether this amounts to genetic predisposition, dose/compound used is unknown (though we can easily stipulate harsher compounds such as most orals, trenbolone etc have a higher predispensity for causing this)
- there is an abnormally high incidence (3x general population according to one study) of cardiomyopathy (associated with deleterious effects on cardiac function) within the AAS using cohort, backing up the claims behind sudden cardiac death and correlation to use
- certain compounds (c17aa compounds, tren) are far harsher on the lipids than others (test, EQ, deca etc) and nonaromatising compounds tend to be harsher than aromatising compounds
- correlation between use and high blood pressure (mechanism now explained), hepatocellular carcinoma, peliosis hepatis, FSGS and more
- rodent and in vitro studies indicate profound cardiotoxicty, neurotoxicity, nephrotoxicity and more to be induced by testosterone and synthetic derivitaves… however rodents have vastly different metabolic and elimination pathways comparative to us… the vast majority of data taken from rodent studies don’t entirely equate to human biology. In one study a HED of like 60mg test weekly for a large man was found to induce extensive cardiac enlargement… yeah… right. In vitro studies can be interesting, but are flawed in regard to the fact that what happens on a microbiological scale vastly differs to that of a macrobiological scale
- many synthetic derivitaves are far harsher neurologically than test
There are many known mechanisms however as to why high dose T would harm the man specified in my described hypothetical scenario
We have no idea regarding
- the effects synthetic derivitaves metabolites have on downstream pathways, coagulation etc (birth control, synthetic progestins triple + the chance of blood clots in females)
I’ve found the fluctuations to be helpful. Consistent fluctuations tho. I think the only way to truly mimic the natural diurnal hormone fluctuation is with cream or prop. @dextermorgan reports that doing a rolling 2 week change from 185/wk to 200/wk and back improved libido as well.
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When you said, “You’re right” were you agreeing with my first sentence there? 