If you’re concerned about fertility, HCG and FSH, but not a female fertility drug. Half the pill is pure estrogen, if it wasn’t for blocking estrogen in the brain, LH wouldn’t increase.
I understand but i have checked that clomid has put my LH and FSH numbers much higher. So since im trying different ways of injecting T, I think in this period of time would be effective in maintaining that, am I wrong? Obviously if I finally get Trt to work ill get on HCG for the long-term
You want to get rid of the clomid and use HCG for fertility while on TRT.
But in that case wouldnt be fsh in 0, also i Dont know if i can get HCG. Wouldnt clomid maintain fertility at least for some months? help!
The mode of action of clomiphene is identical in females and males. Yes its approved to treat female infertility but there is plenty of well designed RCTs available that clomi raises T, improves sperm parameters and improves bone density in men. Thats why its being used off label in men since the 1990s.
Regarding ‘half of it is estrogen’. Its the zuclomiphene isomer:
Repros/Antares Pharmaceuticals develop a pure enclomiphene version of the drug (so only the estrogen blocking part), run RCTs and seeked approval which was denied mostly for this reason; They tested bone density as a primary outcome in a clinical study and interestingly and in contrast to clomiphene bone density didnt improve. This is in agreement with preclinical studies done in overactomized mice which undergo rapid bone loss due to estrogen deficiency.
Thats why ist called Selective Estrogen Receptor Modulator. The zuclomiphene isomer (the ‘bad’ part in your eyes) is an essential component of the clinical efficacy of clomiphene in terms of bone health.
Ok I will start taking hcg but if I took T without hcg for like 3 months now (without much effect) am I at risk? Also doesnt FSH go to 0?
Could somebody recommend me what to do since TRT is not working? Im starting to desperate, thanks
Sure, start reading from the top and you will see the recommendations.
You’re expecting immediate benefits and it’s not realistic. Two weeks isn’t enough time for the half lives to build up in the bloodstream, a very small percentage of T becomes available to tissue in two weeks, the rest is still attached to the ester.
TRT repairs tissue and this takes time and is determined by your receptor sensitivity. Get your Free T elevated and keep it there, then tell me how you feel in 6 months. Your dosage would get me insanely high levels, the fact 200mg isn’t getting the job done tells me you probably need more.
If your levels are high in the first half of the week and low by the latter half, this would be why you don’t notice hardly anything. You need to stick with pharmacy grade T.
I think this may be your problem and why I suggested daily injection because if you are a hyperexreter and choose an inject frequency that’s inappropriate, after a 6 month time nothing will happen improved.
I know it may seem like that but I have already been like 2 months with 200mg every 2 weeks, then two months with 200mg/week and two weeks with daily injections, so its very frustrating fr
What should I do keep doing daily injections? Or start for example a two times a week protocol with higher levels?
Please guide me
So you think that if I stick with daily injections more time it will start to work? It doesnt feel like that honestly but it may be. In that case what dose should I do?
Your Free T levels were never high enough, TT 300-400 FT at 10.7 is low. You never had levels elevated high enough long enough.
You confuse me and I think I am not the only one.
Something doesn’t add up here.
You are obviously concerned about fertility, is that an issue right now (like within the next 6 weeks)?
Your LH and FSH is not suppressed at 200 mg per week?
And you don’t experience any difference on 200 mg a week, not even 1 or 2 days after injection
No difference at all? Than either what you inject is actually not T (what I suspect) or your problem isn’t T related.
Honestly I would stop TRT (blackmarket stuff or whatever) and get under the supervision of a physician. If you have options go on a very low dose of clomiphene (12.5 mg every other day), your freeT wasn’t too low before TRT anyway.
What he said ![]()
Exactly thats what im trying to do, raise my free t. But i cant
I assure you if you inject pharmacy grade T and inject 30mg daily, your FT will increase, maybe you’ll need more if you are hyper-excreting like I believe you are.
This should be your game plan.
I want to keep my fertility yes
Yes some difference like a little harder erections, but its still not enough, like I said before trt it was like in a 20% and now 40% lets say.
But im not getting the complete effect
I was with an endocrinologist but he didnt know shit, said he wouldnt prescribe more than 200mg every two weeks
Ive tried that and LH and FSH went up, but no T
Ok thank you!
Thats what I was doing for the last two weeks or so, in case that was the solution how long should it take for me noticing full effects?
I feel worse or at best a little better for 6-8 weeks, so I wouldn’t expect immediate results. It takes time. Preferably on a steady dose.