Just curious it doesn’t necessarily have anything to do with yalls current situation but have any of yall with ED or libido issues used hard drugs for a prolonged period of time at any stage in your life? Specifically ecstasy, cocaine, or heroin?
Never mate.
Nope
Finasteride?? Have you seen what that can do to guys?
No Does it cause bad effects? I’m not going to take anything till done the research just finding what works for others. The uridine stack seems like a new on to the game.
I have also seen this:
“Take 300 to 600 mg Sulbutiamine and 500 mg Choline CDP daily. It MUST be CDP. Also throw some Catuaba extract in there, I’ve been taking it at the same time and I’m doing great.“
And this:
“Tieneptine salts at 12.5mg 3x a day with l-tryptophan and 5-htp will restore the opiods and serotonin receptors that were destroyed during tren/deca/antipsychotics/antidepressants. Lots of turkey meat and griffonia beans will work. Kind of like Gryffindor magic. Weed works too with or without, it releases dopamine/serotonin. I’m not sure which strain, genome, indica, sativa or hybrid that releases the most dopamine and serotonin. Unless there’s funny stuff in it.”
And finally for the adrenal gland issues this:
“hydrocortisone”
I’m not saying take any of this stuff but if you see an endo or GP and explain what research you have and maybe push him/her into looking at this stuff he/she will be able to advise dosages and time limits not to cause shit like DAWS.
Interestingly after research do you think tren/Deca causes mild form of DAWS?
Done fair bit of research reading research papers and studies over the last few days including 8 hours today on this subject.
Somethings I found which might help you:
That’s the cycle of dopamine creation, interestingly SAM-e is needed just for the last part of the process, makes me wonder if in your case if other areas in the process also has issues and your doing just enough with the SAM-e to feel better but not fix the cycle.
Another thing to check is your white blood cells and in particular neutrophils. They will be affected by low dopamine levels. It’s a good place to help confirm if lack of dopamine etc is the issue as you should of had a white blood cell count check in past to compare. Interestingly I have what I thought was random low neutrophils currently.
Caber will work for some people but not for reason people think. - something else I found. So caber being dopamine agonist will reduce prolactin which would maybe address ED for some people , And for some people the incline of dopamine levels is enough to “rewire” (term used very loosely as it doesn’t rewire) but it can cure/ treat libido issues.
For some others not as simple. But still so much new stuff being found and seeing the right dr who specialises in this area is a good start.
Most people tend to offer various drugs that can be shown to increase dopamine I.e L dopa etc which it does but IMO it also doesn’t encourage the body to repair or fix its own levels that’s why certain supplements I believe dosed well work better.
This website absolute gold mine of good knowledge too:
The adrenal gland argument I’ve seen tends to be dismissed by some papers and acknowledged in others. I definitely can see how it’s an issue.
Truth is tren can cause a number of negative feedback loops from what I’ve seen. If it wasn’t happening to me it would be interesting to study haha! But you even find out shit like BCAA tablets will decrease dopamine. High corsitol sign of stress or adrenal “fatigue” (Again used loosely) will contribute to dopamine dysfunction and it’s also causes the realise of amino acids I.e BCAA.
Hello guys…
I must say this is all to familiar for me! After 6 years I have solved my issues from Deca almost 100%.
I must say that ZEEK is pretty much dead on correct.
I will speak on nandralone as I did not use tren, but both behaving as Progestins in the body make them similar in action.
Deca Dick or erectile dysfunction can happen for many reasons. Mess up your E2 and you have problems, low androgenic androgens and you have problems, low Dihydro-androgens and you have problems, thyroid problems, adrenal problems ( mostly low output) and youve got problems. Psychological erection problems can be two categories, Anxiety and neurotransmitter imbalances. neurotransmitter imbalances are a known consequence of nandralone use. Most guys use nandralone and experience some degree of ED if the metabolite of nandralone ( DHN) dominates over DHT. Now once the nandralone exits the system and testosterone metabolites (DHT and E2) have normalized neurotransmitters take time, but recover back to somewhere near normal. For some men however, there bloods go back to normal and they continue to suffer from Ed and loss of libido ( and many other symptoms, they just dont always notice them unless they are very in tune to their bodies.) Why dont some men recover? Depending on the “SET UP” when the man used the cycle will determine how his recovery will go… if you start a cycle with a weak HPA axis, there is a chance you will have issues when coming off. Dieting and weight loss hurt the adrenal system further, additionally, Nandralone will negatively feedback on the HPA axis and cause severe adrenal suppression. If your adrenals cant recover, ED continues. If the adrenals cant recover, neurotransmitters will continue to be off balance. Your libido is created in the brain. Libido is driven by dopamine, dopamine is driven by hormone signaling, as is other neurotransmitters. Countless guys come in here and say how much Cabergoline has helped them… Cabergoline enters the brain blood barrier and behaves like dopamine ( it is synthetic dopamine in simple terms). Dopamine and Prolactin have an inverse relationship. when one is up the other is down ans vice versa. However, It takes very very high levels of prolactin to cause ED and loss of libido. Now someone is going to chime in and say that they had ED when their prolactin was slightly elevated…yes I believe them but, what were the other pieces of the pie causing the issue? When the cabergoline helped, it was the release of dopamine they benefited from not the lowering of a slightly elevated prolactin. The big question is : WHY DO SOME MENS NEUROTRANSMITTERS NOT RECOVER?" When experiencing this phenomenon some men take massive amounts of testosterone and quess what… it doesn’t help.
This is a very complicated issue and takes time and patience to resolve. I have worked closely with Scally, Crisler and Mariano… I have learned tons about what we do to our bodies by using supraphysiologic doses of androgens. Most importantly, What progestins can do to the brain. ED can happen for many reasons, however Continued ED and loss of libido after nandralone use can be attributed to a brain problem and an adrenal problem. ZEEK is correct in stating that an extremely diminished libido reveals itself as ED. We look at porn and we get a nearly normal erection while we have Deca dick… but yet with a girl its like a rope. Pornography is hyper -stimulation and releases much more dopamine…your baseline dopamine is signaled by proper E2 and progesterone levels. Heal adrenals and progesterone returns to normal. it is possable to heal the adrenals and still have neuros out of whack like in my case. About 10 % of the population has a gene mutation in their Methylfolate pathway… this can make the body and brain struggle to recover. Its worth looking into for those that cant recover. MTHFR Mutation testing. the % of population with the mutation is consistent with the men who dont recover from progestins… Its worth a shot to look into. Men from Mediterranean decent have a high % of having the mutation.
ok enough for now…
If suffering check the following.:
E2
testosterone
DHT
Adrenal output AM CORTISOL, DHEAS, PROGESTERONE ( if in range and under 50yrs, you should be in the upper 1/3 of the range. The lower 1/3 will cause you issues despite what a western physician will tell you)
Thyroid ( by a knowledgeable thyroid specialist)
Once these are optimized and you haven’t recovered, then look into low neurotransmitters…
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One of the most helpful posts I’ve ever seen on this subject! Gives me something to ask the dr to look into! Star man thank you !
Thanks for chiming in mate. It’s really encouraging to hear you have recovered after such a long time.
I’m currently waiting on the results of a very comprehensive adrenal test so that’s the next step for me.
I know that my progesterone has been very low since tren, cortisol seemed okay though.
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How do they test for low neurotransmitters? Or is that a daft question haha
Any available testing (urine, hair, saliva and plasma ) are known to be not reliable …
Symptoms typically dictate any course of action for treatment…
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You mean for neurotransmitters? Neurotransmitters cannot me measured directly. Organic acid testing test for neurotransmitter metabolites and this gives an indication of levels. I do not know how accurate this really is.
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Correct. There isn’t a reliable method currently apart from a lumbar puncture. Symptoms and a screening from a psychiatrist can help with a starting point for neuro manipulation…
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So first things first, see an endocrinologist or an Andrologist. Failing that see neurologist?
Yes, if your Progesterone is supressed after progestin use, this is the body’s response to that use. If left alone, it should recover, however, ive seen cases where it recovers very high and then quickly lowers again. this phenomenon is consistent with PTSD cortisol patterns. Dont be alarmed by this statement, its just observations seen and read in the NCBI journals. Eventually the Progesterone should normalize. During the time it is low, you will be estrogen dominant. This means low libido, fatty man boobs, weight gain that is hard to loose, unstable moods and sometime sleep issues… healing the adrenal system stabilizes progesterone…
Good luck buddy…
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Hi mate, I had been considering seeing Mariano. Would you recommend him for this situation?
Hello James, What are the issues and how long has it been? Please send me details…
In regards to Mariano, Yes, in addition to his help with this Deca problem, he can help with many corrections regarding overall health…
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I have another question. Apart from hormonal /HPTA / dopamine related side effects , can steroids cause ED any other way. Like damage blood vessels etc? Or will you find the reason usually being less to do with blood flow in the sense of bad vessels and heart but more to do with hormones and brain function.
Uh, no.
Deca dick and other issues are almost solely related to hormones.
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I guess if e2 gets so high that you have BP problems you could get some ED? Maybe? But even so that’s still directly related to hormones and would be a tertiary risk.
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