There is no “standard protocol”. Atleast it should never be approached that way. If a guy walks in pre trt with sky high e2 and low testosterone with obesity, poor diet, no exercise regimen, poor sleeping habits, SSRI history, finestride syndrome ect ect ect then I would say he is screwed. There are so many variables that come into play.
Well maybe “standard” was a strong word. What happens is, lots of people go on a regime, adjust that regime until labs look good, and then after comparison with many other people, it turns out there’s a, “common” ratio of T to adex for most people.
Newer people start using that as a jumping off point and it becomes a “standard”. Of course there are going to be lots of people who are not in the majority who will fall way outside of that.
Not everyone but yeah the “standard protocol” is swinging to steer clear of AIs if you can and allow the E2 to come up with the ratio. That being said, I still take a bit as I seem to be a hyper-aromatizer if there is such a thing. Actually, I seem to be really sensitive to Test and respond well to it and I respond well (no crashing) with anastrazole. I just have to make sure I adjust my dose with my T protocol. Right now Im taking 60mg T-cyp x twice a week and am on .1875mg twice a week of anastrozole. I was taking 1.3mg when I was taking 90mg x twice a week. If I dropped it sides crept in.
DIM and Cal-D didnt do anything for me, or nothing noticeable.
That’s interesting what you said about being a, “hyper-metabolizer” of T. Because I think I may have been one as well. I always had consistently great levels at what was a lower dose than typical. Then out of the blue recently, I’d been feeling like crap and my body composition was changing (for the worse), and labs showed that my T levels (both total and free) had dropped by half.
So I started slowly increasing my dose until finally I’m at a 45% increase, and finally feel normal again. But I won’t know the labs until January.
What’s freaking me out is wondering what happened inside me where suddenly the “metabolism” or requirements changed? Because all else in my life is the same and always consistent.
There has been a lot of talk by TRT docs about testosterone resistance. Google “Testosterone Resistance and the Importance of Treating by Symptom Not Numbers w/Dr. Keith Nichols”
All I know man introducing exogenous testosterone is very complicated.
The Endocrine system is wonderful when it regulates itself. So many moving parts.
Lately I’ve been having a lot of e2 issues since I upped my dose from 135-175mg/week. Mainly the brain fog like my head is under water, irritability, soft erections and turtlehead when flaccid, antisocial, can’t get out of bed. It’s benefiting my workouts strength is up but feeling like a crap. First time I’m doing an EOD protocol I’m used to E3.5 it’s strange it’s almost like you can’t breathe, because levels never really drop much and I never had e2 issues on 2x week even at 500mg cycles in the past. I thought if anything more frequency would mean lower e2…
Ive read up on that and bought the book (don’t bother).
Basically just says that if you don’t feel the effects of test, up your dose. And not to be afraid to be well above the ranges.
Excuse my delay but here is my bloodwork protocol. I would appreaciate some help to analyze it! In my country the sensitive estradiol is not available (unfortunately). My free T is 0.509 nmol/l
Merry T-Christmas:)

