Thyroid Nodules + Tiredness

Pharma TRT
1

I’m 25 years old. I live in Europe.I have got Gilbert’s syndrome (increased bilirubin). My weight is 194 pounds (88kg). Body fat 20% or above. Height 5.8 feet (178cm). I started training 5 years ago but I didn’t use to train regularly. I usually train 4 times a week. Each training lasts about 75 minutes. Strength training is my only physical activity.

My diet includes: chicken, pork, herring, salmon, fat cottage cheese, white rice, brown pasta, porrige, flaxseed oil, coconut oil, omega 3, some fruits. I’m allergic to eggs. I don’t use supplements (apart from protein shake after workout). I’ve never used steroids.

I have got two questions:

My problems are lack of energy(often brain fog) and poor regneration ( I feel tired very often). Doctors say they are caused by Gilbert’s syndrome but the problems occure even when I don’t train and biliribun level is low, so I thought they might be caused by something else. Cardiologists say that everything is fine with the hear. I did some blood tests in November last year and docs said everything was fine. Here are some of the results:

November 2012

TSH 3-gen 1,932 ulU/ml (0,55-478)
FT3 5,53 pmol/l (3,5-6,5)
FT4 15,43 pmol/l (11,5-22,7)

I went to an endocinologist, did blood tests again and a thyroid USG. At that time I was overtrained and probably that was the reason of worse results than previously.

March 2013

TSH 3-gen 1,81 ulU/ml (0,25-5)
FT3 3,41 pmol/l (4-8,3)
FT4 14,12 pmol/l (10,6-19,4)

anti-thyroglobulin 47.70 IU/ml
anti-thyroperoxidase 53.40 IU/ml

USG showed I have got 5 noudles: 9x6mm, 7x4mm, 6x4mm, 6x4 mm, 4x6mm. My endocrinologist said that I would need to take T3 in order to stop noudles from growing. He added that it should give me some energy. I have been taking 50mg of T3 (Euthyrox N50) every day for 9 weeks but I don’t feel ANY results. Doc advises me to take T3 till the end of my life to save me from thyroid cancer. Next month I will have another USG to check the size of the noudles.

1)What is your opinion on taking 50mg of T3 every day forever? It seems strange to me. [I don’t enclose my temperatures, because it is not possible to buy an oral thermometer where I live. I can post arm pit temperatures, but in the sticky post it says they are not realiable.]

In the last month I have done more blood tests.

Testosteron Total 7.14 ng/ml; (3-10,6)
Testosteron Free 17.78 pg/ml (4,5-42)
Estradiol 46.04 pg/ml (0-62)
Prolactin 14.32 ng/ml (3-25)

Cortisol morning 18.50 Ug/dl ( 5-25 )
SGBH 22,33 nmol/l (15-100)

Cholesterol Total 145mg%
Cholesterol HDL 53mg%
Cholesterol LDL 63 mg/dl
Triglyceride 43mg%

  1. I am aware that cholesterol is too low. Are the rest of the results ok? Doc says they are, but I don’t trust him.
2

If you do thyroid labs soon after doctor palpates your thyroid gland, you levels will be pushed high.

Post temperatures. The thermometer cannot be placed under your tongue?

How do you react to major stress events? Do you feel stressed out? Can you get tested for rT3?

What is your history of iodine intake from iodized salt? Iodine deficiency can lead to nodules and hyperthyroidism. But at this time, your TSH suggests that you were still hypo. rT3 blocks fT3 and that can lead to higher thyroid hormone levels.

Do you have any hypothyroid symptoms such as dry skin, brittle nails, feeling cold?

3

[quote]KSman wrote:
If you do thyroid labs soon after doctor palpates your thyroid gland, you levels will be pushed high.
[/quote]

The second blood test (the one with lower levels) was done about 2 days after palpation. But I don?t think it could influence the results because the doctor touched thyroid very gently and only for about 5 seconds.

[quote]KSman wrote:
Post temperatures. The thermometer cannot be placed under your tongue??
[/quote]

I thought that a special thermometer is needed to take temperature from mouth. I will check this out.

[quote]KSman wrote:
How do you react to major stress events? Do you feel stressed out? Can you get tested for rT3?
[/quote]

I?ve searched the web and it seems that rT3 test is not performed in my country.
I am rarely stressed. Actually, I would say I?m too chilled out and often don?t care about things my friends do.

[quote]KSman wrote:
What is your history of iodine intake from iodized salt? Iodine deficiency can lead to nodules and hyperthyroidism. But at this time, your TSH suggests that you were still hypo. rT3 blocks fT3 and that can lead to higher thyroid hormone levels.
[/quote]

I haven’t used salt at all for many years.

[quote]KSman wrote:
Do you have any hypothyroid symptoms such as dry skin, brittle nails, feeling cold?
[/quote]

I?ve checked the symptoms listed on wikipedia. The only one that matches is fatigue. Sometimes I feel mentally bad (wouldn?t call it depression) because of the physical status e.g. I am tired and can?t train or even read/learn but at the same time I can?t fall into sleep, so I lay in bed for one hour doing nothing → that affects my mood.

  1. Do you think I could stop taking 50mg of T3 everyday? I’ve read that nodules can lead to cancer only in 4% of the cases, and it seems to me that using T3 till the end of my life could me more risky than leaving thyroid as it is. I could get biopsy of the nodules.

  2. What about my testosterone results? Isn’t Estradiol too high?

4

Can you posts the ranges for TPO and TGAB?

ASSUMING these are using common ranges you have Hashimoto. You can research more about this on sites like STTM.

This leads to nodules and cysts as well as goiter. These nodules can secrete hormones or become cancerous, (especially the cysts if calcified).

Request Thyroglobulin quantitative blood test to check for cancer.

Get LEF selenium and take 200mcg a day. DONT do iodine replenishment. Iodine in salt is ok though.

Get goiter measured. Armour or synthroid at a dose high enough to stop the attack and reduce the antibodies would be best in your case. Never hears of fast acting thyroid hormone (T3) being used alone for hashi.

5

[quote]Tunapancake wrote:
Can you posts the ranges for TPO and TGAB?

ASSUMING these are using common ranges you have Hashimoto. You can research more about this on sites like STTM.

This leads to nodules and cysts as well as goiter. These nodules can secrete hormones or become cancerous, (especially the cysts if calcified).

Request Thyroglobulin quantitative blood test to check for cancer.

Get LEF selenium and take 200mcg a day. DONT do iodine replenishment. Iodine in salt is ok though.

Get goiter measured. Armour or synthroid at a dose high enough to stop the attack and reduce the antibodies would be best in your case. Never hears of fast acting thyroid hormone (T3) being used alone for hashi.[/quote]

I have an enlarged thyroid. I’m curious, why do you say to not do Iodine replenishment?

6

[quote]MytchBucanan wrote:

[quote]Tunapancake wrote:
Can you posts the ranges for TPO and TGAB?

ASSUMING these are using common ranges you have Hashimoto. You can research more about this on sites like STTM.

This leads to nodules and cysts as well as goiter. These nodules can secrete hormones or become cancerous, (especially the cysts if calcified).

Request Thyroglobulin quantitative blood test to check for cancer.

Get LEF selenium and take 200mcg a day. DONT do iodine replenishment. Iodine in salt is ok though.

Get goiter measured. Armour or synthroid at a dose high enough to stop the attack and reduce the antibodies would be best in your case. Never hears of fast acting thyroid hormone (T3) being used alone for hashi.[/quote]

I have an enlarged thyroid. I’m curious, why do you say to not do Iodine replenishment?[/quote]

EDIT: Sorry thought you were NOM LOL.

I asked you for the lab ranges for thyroglobulin AB and TPO AB. Assuming the lab used the standard ranges for IU/ML you have hashimoto. In this case iodine replenishment can speed up the destruction of the thyroid.

You have goiter. This is reversible to some degree with thyroid meds.

7

[quote]Tunapancake wrote:
Can you posts the ranges for TPO and TGAB?

ASSUMING these are using common ranges you have Hashimoto. You can research more about this on sites like STTM.

This leads to nodules and cysts as well as goiter. These nodules can secrete hormones or become cancerous, (especially the cysts if calcified).

Request Thyroglobulin quantitative blood test to check for cancer.

Get LEF selenium and take 200mcg a day. DONT do iodine replenishment. Iodine in salt is ok though.

Get goiter measured. Armour or synthroid at a dose high enough to stop the attack and reduce the antibodies would be best in your case. Never hears of fast acting thyroid hormone (T3) being used alone for hashi.[/quote]

MytchBucanan joined the thread → he has enlarged thyroid. Doc says taht mine is of a normal size:

Left part: 13x15x38mm [ 6x4mm isoechogenic, 4x6mm hypoechogenic noudle ]
Right part: 16x16x38mm [ 9x6mm hypoechogenic noudle, 7x4mm isoechogenic noudle, 6x4mm mixed noudle ]

I had anti-TG and ani-TPO tests made in march. I was overtrained then and TSH3 , FT3 and FT4 were lower than previously.

March 2013

anti-TG 47.70 IU/ml (<100 is negative
100-150 is not sure
>150 is positive)

anti-TPO 53.40 IU/ml (<50 is negative
50-75 is not sure
>75 is positive)

TSH 3-gen 1,81 ulU/ml (0,25-5)
FT3 3,41 pmol/l (4-8,3)
FT4 14,12 pmol/l (10,6-19,4)

My doctor’s idea for taking T3 is to stop thyroid from producing this hormone. Thanks to this, nodules should stop growing or maybe even shrink. But I am afraid that it could have negative consequence if using T3 through the rest of my life.
Doc says that ,apart from nodules, everything is fine. He suggests noudles’ biopsy to check if they are cancerous. I’ll go to see him in 2 weeks, so if any of you have more suggestions to tell him please feel free to post them.

8

Thanks for the ranges.

So it seems TPO is the one that is borderline positive. Keep checking them every once and awhile. Even if only one is positive that’s Hashi.

Biopsy and thyroglobulin quantitive are needed.

You could ask if armour would work in your case. That’s T3 and T4.

9

Thank you for replies.

I measured temp in the mouth after waking up. It was 96.62 F (35.9 C) :confused: I know it’s too low. I will do more measures today and in the follorwing days.

10

I just had my biopsy done. As it turns out, I don’t have an actual enlarged thyroid but a nodule. It was a bit uncomfortable but the pain after was worse. It was not as bad as a root canal, thank God.

11

My average temps:
In the morning 96.8°F (36°C )
After 8 hours 97.34°F (36.3°C)

Last week I had USG done. Thyroid had shrunk by 1 mm. My doctor said I need to take T3 till the end of my life to be sure that thyroid would not grow too big and not develop cancer.
I think I will stop taking T3 because I don?t feel any difference. You say that I have Hashimoto but the only symptom I have is chronic fatigue. I don?t feel cold ? I feel hot all year round, so I’m not convinced about Hashi. Why should I take drugs then?
How can I safely stop taking T3? I?ve been taking 50 ED for 3 months. I thought of taking 25mg for 14 days, and then 12mg for another 14 days.