There are 3 Myths with Regard to TRT

The first myth is that you need to block estradiol. The second is that it causes or worsens prostate cancer. The Third is that you have to donate blood while on testosterone replacement therapy.

I’m guessing you’re saying if you’re on the correct dose none of that is necessary … ??

There is only one such myth: That the internet (and its self-educated ā€˜experts’) can be trusted as a source for medical information.

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When you produce testosterone on your own, or you take it exogenously, it goes down three separate pathways. Testosterone exerts effects as itself directly on muscle tissue, and that’s why bodybuilders want to abuse it. All of the other beneficial effects of testosterone are mediated by the other two pathways, and that is via it’s conversion to DHT or estradiol in the target tissues. So all of the wonderful things that you know about testosterone are for the most part due to its conversion into estradiol. When men block estradiol they are blocking the beneficial effects of testosterone at the tissue level.

With increasing androgen levels DHT and estradiol reach a saturation point. Once the five alpha reductase enzyme as well as the aromatase enzyme is fully saturated with androgen it can no longer produce DHT or estradiol. So DHT and Estradiol will reach a point where they can increase no further, but you can continue to raise androgen levels to the tens of thousands. Neither testosterone nor estradiol causes hypertension, but in fact lowers blood pressure with time. When one first starts testosterone there can be a transient increase in blood pressure and water retention which will resolve.

The secondary erythrocytosis one gets while on testosterone is a beneficial effect and is what increases endurance and what improves healing capacity. This secondary erythrocytosis has never shown any harm in any randomized controlled trial to date, and there have been thousands done. From an observational standpoint, testosterone is presently abused by millions of men worldwide who aren’t under the supervision of a provider, nor do they get blood work, and yet there is no increase in heart attacks, strokes, or blood clots in these men.

There is Zero evidence in the medical literature supporting phlebotomies in men on TRT. In decades of men having a secondary erythrocytosis it has never been shown to cause harm.

Clinics have been phlebotomizing men for decades not based on any harm caused by TRT, but because they think that the secondary erythrocytosis you get from testosterone causes the same issues one would see in a person with polycythemia vera. It does not, as polycythemia vera causes an increase in red blood cells, white blood cells, and platelets and of course platelets clot. There is also a quantitative and qualitative change in red blood cells in people with polycythemia vera. So once again we get to the three myths, which are 1.) you must block Estradiol, 2.) that you have to donate blood because if you don’t there will be harm, and 3.) that it causes or worsens prostate cancer.

Even just a little bit? Do elaborate

Sounds like you just joined a new group and are all hyped up on the koolaid, so let me dispel this ā€œmythā€ for you.

It is correct, eventually enzyme activity will not be able to keep up with the addition of androgens. So e2 and DHT will not climb indefinitely but will eventually saturate. Wanna know at what TT level studies showed that happening? Wanna guess first? Hint: it wasn’t at TRT levels. 3000+ng in the study group. Take that tidbit over to your group and see what his response is

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Thousands of RCTs on this particular topic, you say? Seems like overkill, doesn’t it? After all, you’d think that after the first, say, 500 demonstrating ā€˜no harm,’ researchers would have difficulty securing funding for more of the same. (RCTs are not cheap to conduct.) Frankly, I’m having a hard time envisioning what was written in the grant application for RCT number 2,000 that managed to sway the committee. You’d also think those researchers would find more productive ways to spend their professional time–after all, no one gets tenure/promotion credit for conducting studies that have already been done literally 1000+ times previously. Heck, could you even get a winning high school science fair project doing that?

At any rate, thank you for proving my point.

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Lol, another one who have fallen for the bossa-meme

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A fourth myth is there an optimal T value, usually purported to be 800-plus.

A fifth myth is that a man can actually feel fluctuating levels within the normal range, or that this will somehow affect health. For example. Going from 800 to 1000 on Sunday to 400 to 500 by Saturday.

A sixth myth is TRT producing some great results in muscular gain when it is simply supposed to have normal T values.

Seventh myth: 200 mg or more per week is TRT.

Eight myth: Medicinal amount of T for TRT with other steroids is TRT (ā€œHey guys, I’m on a TRT. I’m only using 100 mg per week but throwing in some halotestin/anavar/tren on the sideā€.)

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Myth nine: TRT is something you simply decide to get on.
I don’t know of any other medicine people decide to get on despite there being no health condition, in this case, actual hypogonadism. I’ve read several threads in which men had normal T values above 500 and tried to ā€œget onā€ TRT. Imagine if someone said, ā€œI’m thinking of getting on insulin/metformin/thyroid/metoprolol/risperdal/etc.ā€

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Myth ten: i can’t grow anymore in the gym, must be time for TRT

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This thread was destined for a gang bang. Lol

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This thread is an insult to Gang Bangs

The 3 Myths come from Dr. Nichols at Tier1

Best TRT Forum anywhere? Makes me wonder what a bad TRT forum looks like

Any Doctors or Clinic owners responding? Or just moths to the flame. Sorry, but you all burned out.

:thinking:
This site + not one of the main Editors/contributors has ever claimed that

Im 100% in agreement with what you posted. But the fact is that no matter what there are a bunch of guys in here that wont listen to me at all either. Its kinda like every man for himself in this forum. You just have to inform yourself and then make your own decisions. So not to add any fuel to the flame but its expected, knowing how different everyone is. I dont take it in any way personal, but some do.

This post is simply dangerous. You can bet too much testosterone can raise blood pressure. Many guys here experienced that, including myself. Are you a doctor??

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Apparently, it looks like ā€œDr Nichols at Tier1.ā€

And pushback against moronic claptrap is an important part of what makes any good forum, good.

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Guy is literally saying theres no ā€œtoo high testosteroneā€.

Ive done 1g blasts, I can tell u for fucking SURE that too high testosterone will give u all kinds of nasty sides, lmfaoo

Yep, its a freaking cult im telling you. I see this shit all over youtube and reddit now, they ALL say the exact same thing, ā€œAI is breast cancer drug!ā€, ā€œe2 has only benefitsā€, ā€œnever block e2ā€, its the same fucking shit repeated all over the internet, these guys are so incredible annoying, fools, lemmings.

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And btw, Nichols is a fool and a dwarf, isnt he like 5Ā“1 ? Napoleon complex and he got called out here before for calling people ā€œlow IQā€ and shit, such a professional EH, lmfao @ trusting these weirdos.

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