Will you need an AI at this dose…Probably
High E2 symptoms and low E2 symptoms sometimes reflect each other. The only way to know for sure is blood testing. Just make sure that you order an “E2 sensitive” test.
You can do this test around wk 5 or 6. unless you feel symptoms now.
Just remember blood testing is cheap insurance against growing a beautiful set of tits!
Sex Hormone Binding Globulin (SHBG) test contains 1 test with 1 biomarker .
Brief Description: The Sex Hormone Binding Globulin (SHBG) test measures the levels of SHBG, a protein produced by the liver, in the blood. SHBG binds to sex hormones, such as testosterone and estrogen, and regulates their availability and activity in the body.
Would that be a good test ? It’s 40$
Are you in the US?
I just did some blood work myself from Discounted labs.
Order Discounted Labs Online Without a Doctor Visit at a Lab Near You
It included all the blood markers I needed.
Full Glucose panel
CBC panel
Total Test
Free Test
and E2 sensitive. All for $110.00 out the door. No questions asked. Results come in an email within days.
Check it out.
500 test is overkill IMO. I’m 42, have been sauced for decades (since I was 18) and the past 6 years a TRT dose of 150mg weekly keeps me at 220-240lbs. I just increase calories if I want to grow. I am a hyper responder but as you get older you realize less is always more in this game, especially if you want to live longer.
Start low, you can always increase…
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I am in the USA California. I used Ulta labs . That one you sent me was kinda expensive for me . That sex binding goblin test was 40$
SHBG testing is not going to prevent you from growing a beautiful set of tits.
The E2 sensitive test will. It’s also $40.00. Cheap insurance.
Besides what is your health worth?
I always get a kick out of guys that can pay for an expensive cycle. Then say that can’t afford preventative blood work.
These are the guys that show up in the forum months later saying “I have ED” or “I have gyno” Can you guys help?
Brief Description: The Estradiol Ultrasensitive test is a laboratory test that measures the level of estradiol, a form of estrogen, in the blood using a highly sensitive assay. Estradiol is a key hormone involved in the development and regulation of the female reproductive system, as well as other physiological processes
Also Known As: E2 Test, Estrogen 2 Test, Estradiol Ultrasensitive Test
Would this be good?
I ordered the sensitive estradiol test and I have an appointment for next Wednesday. I started taking a quarter of 1mg every other day.
yes.
I took the arimidex 2 times last week and stopped. I want to see where I’m at without it. I’ll have my results next week.
Great idea. Let us know when the results come in.
So far my experience hasn’t been what I expected. When I started I was in really good shape and I do lots of cardio. I’ve been taking the test for 5 weeks now and I still have a lot of muscle soreness in my recovery time hasn’t gotten much better. I’ve gained about 10 lb and I am a little stronger and look a little bigger.
Are you pushing yourself harder in the gym?
If so, and you feel like muscle soreness is becoming more of a hinderance and recovery is suffering.
Back off a little. What’s your weekly programing like? Cardio + Weight training.
What’s your diet and sleep look like?
Remind me again. What’s your goal here?
I’ve been a pro cyclist since I was in high school and I had back surgery about 3 yrs ago and I have a little nerve damage in my legs . I know I’m getting older but my power is down and my recovery is poor . Before my surgery I always trained around 14 hrs a week and 250 miles. Now I’m struggling to do half of that. My resting heart rate for the last 30 years has been around 43 now that I’ve been taking the test e it’s been around 51 and my sleep isn’t as good. I’ve cut out beer and I’ve cut way back on candy and I get around 150-200 grams of protein everyday. I’m very suspicious of the gear that I bought. I will definitely buy from a different place next time.
I’m currently taking 0.8 of 250 test E. I skip 2 day and pin . And I take 2 10 winstrol in the morning and 2 at night . And I’ve been doing 1 shot of 500 iu hcg once a week
Remember this.
You went from taking “Zero” steroids to SEVEN HUNDERD AND EIGHTY MG. per week. PLUS 1000 iu’s of HCG
Your test levels went from normal or LOW normal to 3000!
I don’t think you have bad gear.
I think you may have too much gear.
In the meantime you need to GET YOUR BLOOD PRESSURE checked.
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I think you misunderstood me or I wrote it wrong. It’s more like 400 test e a week and 500 hcg a week.
I was taking 1ml of test e 250 2x a week and I cut it back to 0.8 2x a week
Ok…But, don’t misunderstand me when I say.
400mg Test + 280mg winstrol ='s 680mg anabolic load for the week.
Here’s the thing. You should have probably just started TRT and crept up on performance while mitigating any unwanted side effects.
I’m not saying that your reasons are not valid. I’m just saying that trying to use gear to try to get back to performing the highest level is only going to give you a high level of performance temporarily and put a whole lot of stress on your body while doing so.
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Okay I see. You added up the winstrol for the week.
I posted this previously, hope it helps.
ECLIA vs LC/MS/MS TESTING FOR E2
The ECLIA test (aka immunoassay or IA) for E2 management is commonly used for those on TRT. It is not an incorrect test or a test for women, but simply one way to check estradiol levels. The other commonly utilized test is the LC/MS/MS method (aka liquid chromatography dual mass spectrometry, sensitive or ultrasensitive). It is the more expensive of the two. There are inherent advantages and disadvantages to each of these two methods. I have been fortunate to be able to speak with professionals who work with both methods. One is a PhD researcher for Pfizer and the other is a medical doctor at Quest. I’ll summarize their comments.
The ECLIA method is the more reliable of the two in terms of consistent results. The equipment is easier to operate thus accuracy is less reliant on the skill of the operator. If the same sample were to be tested twenty times, there would be very little, if any, difference in the results.
The ECLIA method is not as “sensitive” in that it will not pick up E2 levels below 15pg/mL. If your E2 level with this test is 1-14pg/mL, the reported result will be “<15”. Because of this, it is not recommended for menopausal women, men in whom very low levels of E2 are suspected, or children. In other words, if your levels are below 15pg/mL, and it is important to know if the level is 1 or 14pg/mL, you do not want this test. For us, this is likely moot, since if you are experiencing low E2 symptoms and your test comes back at <15, you have your answer. For a woman being treated with anti-estrogen therapy for breast cancer, it may be necessary to know if the E2 level is zero or fourteen because therapeutically, they want zero estrogen.
A disadvantage to IA testing is that it may pick up other steroid metabolites, which in men would be very low levels, but still could alter the result. Another potential disadvantage is that elevated levels of C-reactive protein (CRP) may elevate the result. CRP is elevated in serious infections, cancer, auto-immune diseases, like rheumatoid arthritis and other rheumatoid diseases, cardiovascular disease and morbid obesity. Even birth control pills could increase CRP. A normal CRP level is 0-5 to 10mg/L. In the referenced illnesses, CRP can go over 100, or even over 200mg/L. Unless battling one of these serious conditions, CRP interference is unlikely.
The LC/MS/MS method will pick up lower E2 levels and would be indicated in menopausal women and some men if very low E2 levels are suspected and it is desired to know exactly how low, children and the previously mentioned women on anti-estrogen therapy. It will not be influenced by elevated CRP levels or other steroid metabolites.
While some may believe the ECLIA test is for women, on the contrary, as it pertains to women on anti-estrogen therapy, such as breast cancer patients, the LC/MS/MS is the test for women as CRP levels are a consideration and it is necessary to know if the treatment has achieved an estrogen level of zero.
On the other side of the coin, LC/MS/MS equipment is “temperamental” (as stated by the PhD who operates both) and results are more likely to be inconsistent. Because of this, researchers will often run the same sample multiple times.
It is not clear if FDA approval is significant, but this appears on Quest’s lab reports: This test was developed, and its analytical performance characteristics have been determined by Quest Diagnostics Nichols Institute San Juan Capistrano. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes. This statement is on LabCorp’s results: This test was developed and its performance characteristics determined by LabCorp. It has not been cleared by the Food and Drug Administration.
It is unlikely that any difference in the same sample run through both methods will be clinically significant. Estradiol must be evaluated, and it should be checked initially and ongoing after starting TRT. It obviously makes sense to use the same method throughout. Most important are previous history and symptoms related to low or high E2. Those are correlated with before and after lab results. Any estradiol management should not be utilized without symptoms confirmed by lab results.
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