Standard Rx guideline is once weekly dosing.
Very different dosing in TRT vs TOT land.
Starting Dose and Dose Adjustment
The starting dose of Xyosted is 75 mg, administered subcutaneously in the abdominal region once a week.
Dose adjustment
Measure total testosterone trough concentrations (measured 7 days after the most recent dose) following 6 weeks of dosing, following 6 weeks after dose adjustment, and periodically while on treatment with Xyosted. A trough concentration between 350 ng/dL and 650 ng/dL generally provides testosterone exposures in the normal range during the entire dosing interval.
Decrease the dose by 25 mg if the total testosterone trough concentration (Ctrough) is ≥650 ng/dL.
Increase the dose by 25 mg if the total testosterone Ctrough is <350 ng/dL.
Maintain the same dose if the total testosterone Ctrough is ≥350 ng/dL and <650 ng/dL.
Completely consistent with good ole chart:
This never gets old: