Did you notice any aesthetic benefit? (I recall somewhere else wherein you adknowledged using 10mg stanozolol/day to lower shbg). Did 10mg/day induce any aesthetical impact? Did you suffer from joint pain (many anecdotally get joint pain on winny), recovery time in the gym (was it increased/decreased?)
Also (probably doesn’t relate to 2.5mg/day) but statins + c17AA AAS are generally not the greatest combination
Totally unrelated, but just had my ECG done. I emailed you the results, if you don’t mind taking a peek! Doctor said everything looked great. 
Just to be clear I no longer use low dose stanozolol (Winstrol) or oxandrolone (Anavar) to lower my SHBG. When i did, i found that 5mg stanozolol (2.5m 2X/day) per day was sufficient. With oxandrolone, I needed to do 5mg 2X per day (10mg/day) for the same effect.
I did not notice any joint pain. I don’t think recovery time was any better, it was minimally effective at that low dose, if at all. I did do a short trial of a larger dose of Anavar (30mg/day) and did notice some awesome pumps in the gym. however, that’s not my goal, so I don’t do that any more. I just wanted to try it.
In terms of AAS anecdotally. Testosterone/nandrolone appear to be significant aggravators regarding autonomic dysfunction. I’ve never used stanozolol and presumably never will thus I can’t comment or give an anecdotal comparison.
I was running higher test than you when running stanozolol. It took about 3-5 days to kick in. Vascularity was amazing on week 2-4, but I was about 12% body fat. You might see it sooner. I was also running masteron, so how much vascularity was due to the masteron and how much the stanozolol? I’m not sure.
Strength gains were surprisingly as good as anadrol for me, but I had to supplement taurine to reduce the cramps in my feet. I’m not sure how well that worked to be honest. They weren’t debilitating or anything, just once in a while they would randomly cramp up and I would have to pull my toes back.
As for oxandrolone, I’m not a big fan. You don’t really get a “I’m on steroids” feel from it. It’s more of a low risk low reward type deal. It’s also processed by the kidneys which turns me off to it. It a way I think it’s more dangerous than taking a lower dose of something like stanozolol and letting your liver regenerate afterwords.
I’m taking a little bit of oxymetholone right now as I don’t always make the best decisions. The quick uptick in strength, the crazy fullness and increase in vascularity etc is unparalleled; probably due to the higher dosages per tab as opposed to oxandrolone, stanozolol etc. Lot of water retention though
I don’t take harsh substances like this for more than 5-7 days at a time as the beneficial effects appear to peak for me quickly prior to chronic heartburn, drop in appetite kicking in.
Thought you might find this interesting. I’m unsure as to how strong stanozolol is in terms of mediating sympathetic drive. I tend to believe the AAS that are strong modulators of sympathetic drive are probably going to be quite damaging due to the long term effects of consistently being in a “fight” (fight/flight) esque. This includes testosterone; in higher dosages I don’t believe testosterone is one of the more “benign” substances.
It only takes around seven days for effects on serum lipoproteins to peak, following which it doesn’t take very long for lipids to normalise when use is ceased.
Document heart rate variability and RHR + post workout HR recovery if you have the time. I’d be interested to see how stanozolol impacts these parameters.
For the last variable I’ve found cardio is the best way of ascertaining impact. Get on a treadmill, run a few miles. Check HR before, during, immediately after (like 90 seconds after) and 1.5 hours or so after. Do this before and whilst on the winny.
If you can’t run a couple/few miles as but everyone can (apparently I have unreasonable expectations as to what should constitute a normal level of fitness), cycling will do the trick.
Tell me how the winny effects lipids at 25mg/day. I have a rough estimate as to what 12.5mg would do. Get SHBG checked too… This is exciting
I wish I had the balls to pull labs on day 5-7 of running something like oxymetholone… I don’t want to see my HDL reeeeeaaalllllly low again though.
Above 15mg/dl coupled with a HDL/LDL ratio of less than 1/4 and I’m not freaking out. My standards are quite low.
One question I have is why winny? I know you don’t like var, but other options exist (tbol). Tbol would be milder on lipids (at least that is the general consensus). Probably a lot nicer for your joints too.
Sorry I’m advance for using the street names for these compounds.
It isn’t. Plenty of anecdotal bloods with people who have HDL in the low/mid single digits from tbol use as an independent variable.
Probably cuz winny is fcking EPIC!!! 
Injectable proviron would probably be very good for “drying out” albeit not conducive for mass gain (affinity for 3a-HSD enzyme). I have a means to procure this, but it’s a cocktail of injectable proviron, turinabol, stanozolol and oxandrolone.
Not a chance in hell I’d take that. Proviron has an oral bioavailability of around 3%, look at the results people get from 50-100mg orally. Imagine injecting 10-20mg/day with a far, far, far, far higher bioavailability.
It’d screw lipids up fiercely though
My dick doesnt work too good for 3-4 hours after taking proviron. I hate it.
I can’t get the link to work. Legal reasons make the decision more clear to me. If that was a non factor, I would use Tbol, even if the lipid impact is equal. The impact to joints is not equal, and as a powerlifter, I would only use something like winny for a very short period to increase strength temporarily. The powerlifting alone is enough on the joints for me.
I think lots of folks would still use this description (though obviously people have taken dosages to EXTREMES these days). I tend to think of performance TRT – like my 238/week – as ‘supraphysiologic.’
Do you have behcets disease or HAE?
Well… It is, but supraphysiologic merely pertains to higher than a male would naturally produce. If I recall 125mg/wk has also been deemed supra within literature
200mg is typically around 1.5-2x the top end of natural for most
Are you still covid positive? If not, stop worrying about cytokine storm
As one individual with chronic pain… I’ll tell you… It… Can… Always… get… worse
Do you take medication to control pain? I’m about to rant!
Traditional pain meds are getting harder and harder to get on script for due to those who abuse them for their euphoric effects. In Australia they’ve removed all indications for use as an aid to combat chronic non-cancer pain. What’s worse, I have to go in for a refill for every twenty tablets I take.
I understand prolonged use coupled with a questionable psychiatric status (present with many chronic pain patients) can lead to overt dependence and negative outcomes (hyperanalgesia, negative effect on BMD, tolerance/dependence etc).
But for intermittent use for breakthrough pain (say 2x/wk or so) I’ve found they are tremendously effective. Soon after I was put on TRT I was on daily opiates. I stopped taking them because I felt as if I no longer required them. No withdrawals, I never built a tolerance etc; I suppose this was partially associated with the fact I can honestly say there was no recreational facet associated with my use, ditto for today.
I was using them to reduce physical (not emotional) pain and discomfort… That is all… I took other things to deal with the emotional pain 
jokes… sort of…
It’s amusing however, as if I hypothetically required a few tablets during a particularly bad week and couldn’t acquire them… It’s not as if I’d just stand by and say “well… Okay, looks like I’ll deal with this”, no… I’d 100% buy them off the street, and what you’d acquire through this avenue would typically be far more potent, not to mention potentially dangerous.
The government here has left chronic pain patients out in the cold with no other viable alternative. Opiates don’t appear to be very effective long term aside from within specific anecdotal cases. But as specified they are effective for breakthrough pain even when used over long durations of time, so long as the use isn’t daily… It’s very difficult to get in for a ketamine infusion, corticosteroid use generally isn’t sustainable either. Neuromodulators like Gabapentin and pregabalin are somewhat poorly tolerated (esp the latter) and many don’t seem to respond.
Then there’s the depression aspect of the chronic pain. I believe a holistic approach is extremely important. Especially with pain sensitisation pathways in response to a sedentary lifestyle. For some, they have no choice; some conditions really are SO painful that getting out of bed is near impossible. But for those such as myself (not going into specifics) regular exercise (even intense exercise… but build up to it dammit!), therapy, social interaction and generalised productivity does appear to make a difference. My case was unique given that despite unrelenting pain I strived and still strive to exercise as much as humanely possible because I love it. Other holistic measures (therapy, getting out, physiotherapy etc) are all checked off. To tell me “you just need to exercise more” would be incredibly insulting given I probably put more hours into the gym per week than 99% of the population.
If you theoretically have a housebound patient who doesn’t interact with others and merely sits down fixating on their pain, its conceivable that this individual is probably going to “need” more medication. At the same time here our government has swung the pendulum so far one way. There are those who fit the criteria to theoretically be able to take these meds in as safe a fashion as they possibly could take them, yet they’ve now been cut off entirely and are no longer able to live a normal life, work, play wth their kids etc. It’s pathetic considering we never had a widespread opiate epidemic to begin with aside from within a few select neighbourhoods (usually heroin).
We do however have a raging, systemic issue with methamphetamine; yet amphetamines were exempt from these new ridiculous restrictions. It appears as if this issue has been polarised and the Australian government is following in America’s footsteps… because??? It’s not as if we are enveloped within a remotely similar set of circumstances but I digress. If this were a logic based policy, amphetamines would have been subject to similar regulations, yet those with ADHD can pick up a bottle of one hundred tablets at a time from the pharmacy. I wouldn’t agree with the undue restrictions being imposed on any medication. Some people require certain medications to live a normal life, or whatever semblance of normality they can find.
For many with intractable chronic pain, simple lifestyle modification is not enough to reduce discomfort enough to enable one to live a normal life.
The fact my close relative with terminal late stage cancer is complaining of discomfort/doctors appear afraid to increase the dose (for someone that is already dead…) irks me. It’s as if quality of life is on the back burner. Should someone like this need to go in for a repeat over every twenty tablets they take? Absolutely not
Always loved your rants