Started TRT 6 Months Ago. Lot of Side Effects

Ok you still have injections stored in your fat and muscles. Your e2 will be high. Your free t is probably sky high. In 4-5 weeks it should be down to 10-20% stores. Your labs a few weeks ago should super high e2 levels. I would not be surprised if that’s causing the issue.

I switched to cream without waiting to and my erections we’re gone until 4 weeks in. Now it’s better and progressively seems to improve as the cypionate leaves my body.

Did the doc tell you e2 is probably high and causing this?

I had the same issue when I switched to cream. Couldn’t get it up and when I did it was 60%. I know your having this issue pre defy change but this is your situation now. You need to stabilize and don’t worry your sex health will come back. Why wouldn’t it? You were on and off with your protocols over the months and that in itself isn’t helping right? So stay positive my friend.

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Thanks @enackers for encouraging words.

ED was on injections too and I had been a consistent protocol for at-least 6 weeks. Surprisingly, no ED when I was inconsistent. I mean, no ED as long as I took Cialis.

e2 is high and the doctor said he prefers it to be in 25 to 35. And asked me to .125mg Arimidex twice a week. Which I’ve started. I’ll get tested again next week to see what new e2 and T levels are. I’m assuming a little bit of T would still be there from previous injections though so can’t trust total T levels. But I can get tested again in a week or so after that.

If it took 6 weeks to build up in your system, then it’ll take 5 or 6 weeks to dissipate. The e2 will drop the further out you get from last shot. I think it’s e2 but I’m no doc or a professional. When I had high e2 my guy didn’t work at all and Zero desire to have sex either. I took 2 clicks am and Pm for three weeks and it helped. I truly think once e2 is fixed you’ll be fine. At least it’ll work again:

Suggestion and what I did. We have the exact same issue. Injections to cream lol.You should take half your cream until you reach week 3 or 4. It’ll help. Or take 2 in am and 1 pm. You have plenty of T stored up and you won’t notice a difference.

Lastly, pay attention to your body and make sure you don’t crash e2. The further out you get the less T is converting so keep that in mind to.

Keep us updated. I’ll let you know in 2 weeks how I’m doing. That’s when all the cypionate will have left me and I’ll be on 100.% cream.

More free t does not equal more labido. Truly sucks.

Same here, first couple weeks on starting a new protocol I have erections, approaching the 6 week mark erections start going soft, high E2 is the problem. Also I hardly urinate much during the day when E2 is high, it’s like high E2 does something to prevent erections and urination from occurring very often.

If I take a few powder grains of AI, it’s erections for the next 12 hours. Someone needs to redesign anastrozole for over-responders.

I have significant weight to lose.

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are you saying that injections I have done weeks ago are still seeping out of my glute fat and into my bloodstream?

thats interesting… so you are just increasing the differential bewteen E level and FT level and WHAM the libido returns?

That is what he is saying. I hope you don’t believe it. This guys has never heard or doesn’t understand a drugs half life.

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What I really need to do is decrease the ratio of fat tissue, I’m 240 and my normal weight is 160 throughout my 20’s when I was healthy.

The body fat is the main cause, the estrogen is the result of the extra weight.

I’ve lost fat around my legs and hips in just 5 weeks on this new protocol, even my hands look more boney and veins are starting to show in my legs, arms and erections when I have them.

I may be SHBG on the lower end (22), but my receptors are very sensitive to androgens.

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If he switched to cream the day after taking an injection. Then he still has it in his fucking system guy.

So I’ve been on new cream based protocol for a week

  • ED 2 clicks (each click is .25ml) of 20% T cream (200mg/ml so 2 clicks is 100mg). I apply 1 click on scrotum and 1 on neck.
  • HCG 500 iu twice a week
    and still suffering from no libido and erectile dysfunction

here are the results:

  1. Total Testosterone: 1434 ng/dl (range: 250-827)!!!
  • I’m reducing my cream application now. This is too high. Acne is popping up too. On injection I was in 800s, should try to reduce cream to a level where it keeps me at 800s, not much higher.
  1. Estradiol (E2): 81 (range < 29)
  • perhaps need to start Anastrazole. Haven’t started it yet.

Also, I did a 4 point Saliva Cortisol test and got this:

  1. Morning (7:45 AM) sample: 0.19
  2. Afternoon (12:45 PM) sample: 0.32
  3. Evening (4:45 PM) sample: 0.06
  4. Night (11:45 PM) sample: <0.03
    Range:
    8-10 AM: 0.04-0.56 mcg/dL
    noon-2 PM: < OR = 0.21 mcg/dL
    4-6 PM: < OR = 0.15 mcg/dL
    10 PM-1 AM: < OR = 0.09 mcg/dL

My thoughts / next steps:
Sounds like my Cortisol is on the low side and perhaps I’m suffering from Adrenal Fatigue (not enough Cortisol production). Explains lower-than-usual energy levels since I started TRT. I wonder if TRT lowered my cortisol? Because pre-TRT even when my total T was < 200ng/dl my energy levels were good. Not sure what to do. Would hate to go on something as strong as Prednisone.

No improvement in libido. I’d imagine it is related to E2 being so high but I saw a bunch of videos and read a bunch of forums as well as the site TOT Revolution (Jay Campbell) and they think E2 as high as even 100 is not a big deal and won’t negatively affect libido. So, to take Anastrazole or NOT?

Hello All -

My Erectile issues are still not fixed. Low libido and low erection even with Cialis/Viagara. Can’t hold erection, it goes soft in a minute or so.

I read somewhere about Mesterolone / proviron can help with libido. Is it true? Anybody has experience with it?

Don’t listen to Jay Campbell, I also follow his advice of more frequent injections instead of twice a week and my E2 went from 49 to 59, my SHBG from 35 to 50, and my FT went down from 30 to 20. The higher my E2 is the worst my erections are, I don’t care what some “experts” are saying. My erections were better when my E2 was lower

You should understand your case isn’t typical, you’re an outlier. I don’t usually see many cases where estrogen increases on more frequent smaller injections.

It’s well known many men find daily injections works great to combat estrogen conversion issues and you’ll find many different forums preaching daily protocols for those with estrogen issues.

Well, I was on taking 50mg Proviron ED, and two weeks before the blood test I was taking only 25mg Proviron ED, maybe could be that. Or when you do more frequent injections your SHBG usually goes up and that is a fact.

Did you start out with high SHBG

If so then daily might not be optimal.

If your SHBG is rising on daily it means you’re going to need more test per shot to drive it down.

2 or 3x per week injections might be more your speed.

Yes, my SHBG is always higher than 35. I think I should drop my test from 100mg twice a week to 90mg twice a week, drop the Anastrazole and keep Proviron at 25mg ED, Proviron helps me with erections and libido. I told my Practioner that would be good idea to lower the dose, but he said is better to keep it high and add Anastrazole, all the TRT clinics in Arizona follow the same protocol, that is what Dr Rand Mclain does

Is true 100%. Proviron is the only med that helps me with erections

honestly man i feel like you’re doing too much thinking.

It feels like you’re afraid of doing the wrong protocol instead of finding the right one.

What happened after you did 100mg twice weekly for 8 weeks. Were your numbers okay? symptoms?

On 100mg test twice a week, no AI, no HCG:
FT:30
TT:1350
E2: 49
SHBG: 49
On this protocol my erections weren’t great. Adding Proviron changed to better

i see why proviron would.

That SHBG could be a tad lower and I’m sure proviron aids in that.

I do wonder why your shbg is still so high though? Does everything else in your bloodwork check out.

Also, even though this goes against the usual conventional wisdom but… have you considered one a week at 200mg?

I’m hesitant about saying go about 200mg because you have high levels already, but to drive that shbg down, it may be worth a try.