Hello all. I have been on test cyp 140 mg/wk and arimidex .5mg 2x week for almost 5 months now. My current E2 level is 47, but was previously 68 when I was taking .25mg AI 2x/week. Also on daily DIM/Clomid to preserve fertility. Total test has remained around 1300. Since I am high converter my clinic wants to up my AI dosage but I am not sure this is a good idea.
For the past two months I have been experiencing severe daily fatigue. I simply cannot get rested. I was diagnosed with hypothyroidism several years ago but kicked out of it with diet and exercise.
My fear is that TRT has now brought back my hypothyroidism. Before starting TRT my bloods stated that my TSH was 4.7 which is high (borderline hypothyroid but bearable without meds). Most probably this will have increased since then.
I am not sure if the fatigue is coming from the AI, high E2, high TSH, or hypothyroidism. At this point I am about ready to do a PCT and hopefully the fatigue will go away. I was feeling better during the first month or so, but the fatigue at this point is just not making the whole process worth it. Just trying to get some advice. Thank you.
I would be willing to bet that, if you did LH/FSH labs you would discover the same thing as other guys on here. The Clomid is not preserving anything at all while youāre on injections. HCG would, but thatās not what youāre taking. Find a different practitioner, preferrably one that knows what heās doing. The Clomid and/or the AI are the probable root cause of your problem.
The clomid and lower dosage AI never really made me feel fatigue like this. It wasnāt until I upped the AI the fatigue really started to kick in. The clinic I am going to wants my E2 to be around 20-30 and will probably try to up my AI. Not sure I want to go that route so considering just stopping TRT and see if the problems subside. Thanks!
I suggest dropping the Clomid and the AI, and looking for a different provider. This one is a little out to lunch. There is no reason to tryt and maintain that range on TRT, unless a specific medical condition pops up requiring it. The Clomid is not meant to be a long term drug for anyone, and neither is the AI. You ideally use the fewest number of things possible to achieve your result, and there is no medical reason to be concerned with getting E2 under 30. Seriously, they are screwing you up. Fertility can be achieved through HCG or other drugs when you actually want to be fertile, and you are not necessarily infertile on TRT anyway.
I totally agree with you. After researching Clomid everyone says it should not be used in combination with test. I am losing faith in this clinic the more I research. Less is better, I agree with you again. My main concern is that without AI my E2 will probably be over 100+ which could possibly lead to gyno, etc.
Since my E2 has lowered and fatigue has increased it is most probably not the E2 levels at all causing the issues, unfortunately I donāt think the clinic is too flexible on their E2 protocols.
Ditch the AI and find a new doc. The whole 20-30 range is bro-science that is dying a slow death and has no justification in the medical literature. Youāre even demonstrating it yourself as the lower it gets the worse you feel. There might be one man in ten thousand that might need an AIā¦ Maybe. Youāre not that guy.
Best doc I know in Ohio is Dr Eric Serrano. Brilliant physician and good friends with John Meadows. Heās helped many family members and close friends. Heās in Pickerington.
Iād much prefer a place like Elevate Menās Clinic versus defy for telemedicine. If they are using an AI by default, itās an indicator they have zero understanding of hormones.
elevatemensclinic dot com
I have no affiliation. They are excellent at what they do so I send people there, particularly guys seeking telemed.
Appreciate the info! Yeah I have a meeting with the clinic in a few weeks and will be looking to find something new or may just discontinue for the time being. Thanks again.
I have a ton of content on the TRT and Hormone Optimization YouTube channel. Great place to learn about this stuff. Itās difficult to only rely on doctors in this area as the vast majority are somewhat clueless on the subject.
The whole lying to you about what Clomid does thing should have been the giveaway. FYI, if my TT and e2 were at you levels Iād feel lousy too. Not everyone is going to be range-bound, and some of us feel great with higher e2.
BIL is in Ohio and heās using Evolve (every one of these goddamn t-mills uses the same kind of dumbass name), they didnāt even discuss AI, and they gave him HCG because fertility is a top concern of his. So youāve got some options. Reality is that you have a credit card which is the only preexisting condition necessary for 9/10 of these places. Choose the one thatāll work with you the best and go from there.
Depends a lot on who you get thereā¦ theyāve never pushed AIās on me but ask every time if Iām having āhigh e2ā symptoms, but leave it alone after that. Iām sure some of their docs/NPās are more in the ācontrol e2ā route than Saya is
That being saidā¦ Serrano is probably as good as it gets. If he were closer to me, thatās where Iād be going.
Closet good doc I know would be Dr. Jordan Grant but heās up in Paris, TX which is quite a ways from you. He āhasā done some telemed on occasion.
