Pituitary Adenoma Consequences on Muscle Gains and Sexuality

Pharma / TRT Testosterone Replacement
1

iam in the late 20’s new here and hope someone can help or share a similar story.

I was dealing with fatigue , sleep problem difficulty getting size , iam slim/lean even though i eat very well follwing a coach in nutrition ,and been persistent working out since more than 3 years ,.
I also have sexual problems (ED and Premature ejaculation) ., my libido is not at the top but i still have enough drive .

Recently i did blood check , everything came ok , only slighty high prolaction ( was 21 , and range is 4-19)) and slightly High LH. ( I don’t know the reason but my doctor only ordered free testosterone and not the total ( free test came back 421 (range is 196 -636 pmol/l) ) which is normal range I guess.
Is the free testosterone more accurate , significant than the totale ?

Doctor doubt about pituituary tumor , and send me for IRM.

Did IRM and was 2*3 mm microadenoma . ( Which is very small one)

Now waiting for the endo consultation (after two weeks). Meanwhile , i decided to restest prolactin and LH , FSH level to be sure.
Results came back in normal range now ??? i was dissapointed because i was hoping its prolactinoma.
prolaction 14.5 (range 4 -19)
LH (6.3 (range 1-7)
FSH ( 3.7 ( range 1 -8 )

i also did GH and ACTH blood test( i think i should have done IGF-1 and cortisol instead, they are more significant)
.

what others hormones can I test ? I already did TSH and estradiol and were in the range ( didn’t do t3 ,t4 though because TSH was in the range)

what kind of adenoma is this , and Do Caber improved sexual and gym performance ?

2

Normally with LH near the top of the ranges you should see Total T near the top as well, Total T is more accurate than Free T. In range doesn’t mean much because you can have people in range and be symptomatic, doctors chasing numbers is not the correct path forward, it’s lazier and easier for them.

Treating the symptoms used to be the way in medicine, now it’s treat the ink on the piece of paper. If your a guy who functions better at the top of the ranges and you’re at the lower end of the ranges, well your going to be symptomatic and low for you.

Free T can be elusive, one hours it’s midrange and the next it’s low, Free T has a very short half life and is released in micro pulses throughout the day. You’re missing a lot of tests and don’t have enough for a diagnosment. Prolactin is fine, TSH can be in range and you could still have very low free thyroid hormones. This doctor can’t help if he doesn’t understand that.

TSH doesn’t tell you squat about thyroid free hormones, all it tells you is the thyroid is being stimulated, doctor is making the assumption that thyroid free hormones are alright without actually checking, pretty stupid if you ask me. It would be the same if doctor checked LH and assumed Total T and Free T were fine based off the fact that LH is stimulating the testicles without actually checking.

You can check thyroid status by measuring oral body temperatures upon waking and 2pm afternoon using a glass thermometer. Body temps will reflect Free T3 status, if body temps are normal you can forgo thyroid testing. Most people in UK are iodine deficient do to not using ionized salts.

Most thyroid doctors are subpar failing to comprehend the basics of proper testing and the importance of testing free thyroid hormones (Free T3/Reverse T3). Tests needed are estrogen, SHBG, 4-point cortisol test, ferritin, Free T3, Free T4, Reverse T3 and antibodies. Low thyroid function has the same symptoms as low testosterone, including ED. I expect your doctor to refuse most of these tests do to cost, it may prevent a proper diagnosment.

3

First , thank you very well , i appreciate your help .

1- so with high LH i should expect high test , right ? that means if i have high LH (which i have , and normal testosterone , its like having low T ?)

Doctors are so lazy to do efforts , i think only specialists can helps , but here in Canada , i have to wait long time to get an endo (my appintement is within two weeks now) and i wanna make sure i have everything that can help him , then he wont tell me do this tests and wait another month again.

What made you think about thyroid problems ? i thought my problems are related to the pituitary , because they found small thing 3mm that they guess its a microadenoma. or probably adenoma and thyroid problems are realted

in the first test done doctor tested TSH and results came 2.66 (range 0.32- 4 mlU/l) so thats why he thought thyroid is fine , but apparently TSH could be fine but not T3 and t4 right ?

Also he tested Estradiol and was 113 , range is < 162 which is fine . (i guess estradiol is estrogen level )

So to help the endo , i will do , SHBG, 4-point cortisol , ferritin , Free T3 , free T4 , antibodies , and Total T ( because i only tested free T )

4

Most really good thyroid doctors start to suspect thyroid problems when TSH is 2.5>, this is a problem in the making and always leads to problems down the road. What you have to understand is how doctors are trained, they treat disease and disease is defined be TSH over 4.0 mlU/l. They aren’t concerned until you hit 4.1 mlU/l, the problem with this is you can have low Free T3 or high Reverse T3 and still have normal TSH or within range and still have symptoms.

Thyroid is very complicated for most people to be able to comprehend, so not every doctor is going to have the intelligence to fully comprehend thyroid matters. This doctor is cutting big corners by skipping most of the testing needed and is a bad sign he is saving the state healthcare the cost of having to run these very necessary labs.

You may need to go private clinic and pay out of pocket to receive proper care.

5

i think thats what i will do .(private clinic)

I checked some in my areas , and they mostly talk about BIO IDENTICAL HORMONES.

I still think that this pituitary small tumor is causing all my problems.

6

Your prolactin says no, prolactin needs to be elevated for this to occur. If LH is high and T is below midrange that would mean testicles are responding poorly.

7

Yes i agree but the pituitary gland is the master gland , responsible for all hormones not only prolactin. LH , FSH , prolactin , Growth hormones , Cortisol…
example , my high LH level (first blood test slightly above range , and second blood test was in the range but high) is not good sign. with FSH in the low side .

8

If what you’re saying is true, then it would mean testicles are done or SHBG is elevated. FSH is about sperm production, LH about testosterone production. If the pituitary gland detects less than optimal testosterone being produced it will crank out LH to encourage the testiscles to get to work, if that doesn’t happen it will increase LH yet again until testosterone is being produced.

If testicles are damaged LH will continue to increase.

9

yes i think that refers to primary hypogonadism.

Problem is my Free Testosterone level are in Normal normal range not even low Normal.

10

A perfect example, my TSH is .9 which 1.0 is considered optimal, yet my Reverse T3 is 22 ng/dL within 9.2 -24.1. TSH is unreliable.

My Free T is better than midrange, yet I feel terrible, I need Free T to be at the top of the range or higher to feel good. Total T is 376, Free T 15.1 (6.8- 21.5) and no erections.

These are the testosterone levels of some 80 years old, all while Free T is better than midrange. Still think your testosterone is alright just because Free T is in range?

This is the problem with doctors, they think that because you’re in range that you are normal.

Nobody knows what normal is for YOU, only everyone as a whole and to me that’s pretty vague.

11

Iam going to Test my T3 , T4 to see if I have thyroid problems

But whats solution if you have Normal T but you need to be in high T to feel good ?

TRT ? I am still scared of TRT idea , as I am young and planning to have kids in the future

12

I have some surprising news guys , and really need some help.

Before getting private clinic , I decided to see what the endo will say (my appointement is next week)

So I went to a physician asked to do some tests for thyroid as well as ferritin and many others , he said no need for that you should wait endo appointement . he just accepted to do testosterone test ( remind : I did Free T test and come back normal range)

So results of total T are surprising ( 770 and range is (242-830) ng/dl) which is in the high range. I took it just half an hour after waking up , so probably that helped also I take some T booster (ZMA + tribulus +GABA). my Free T is in normal (does it mean I have high SHBG levels?)

any explanations ? I have high T , but I get tired quick , insomnia problems , mainly bad sexual performance ( ED + PE) , I am lean but struggle to get size , I go to gym since 2-3 years with good diet , I tried both very high and normal calories methods.
remind : I was diagnosed with small adenoma in my pituitary gland

13

If you’re having problems scoring those numbers it’s either high SHBG or thyroid.TSH in range doesn’t meaning anything by itself, thyroid free hormones (Free T3, Reverse T3) have greater meaning as TSH is unreliable.

I’m my experience endos are useless for anything related to TRT, it’s not usually practiced by most and it shows, urologists are the same.

14

Endo will for sure check my thyroid if its not Testosterone problems (even though I feel I have small testicules and slightly unsized ( but apparently unsized testicules is something normal)

So about thyroid , I check both hypothyroidism and hyperthyroidism symptoms . I have some of those symptoms ( Premature ejaculation , dry skin…) but I don’t have something like loosing/winning lots of weight in small period. I have high metabolism but I don’t get too skinny neither.

I will check more SHBG problems