Overwhelmed Looking for Advice

Yes, it can. The intent makes no difference. If one taking 100mg struggled with being anxious, depressed, not “stable” or whatever, I think it follows that one taking 600-800mg would have a greater chance of a negative result. One focusing on levels being stable and “smooth” in an attempt to “dial in” their protocol should try increasing testosterone 100mg per week for several weeks. Perhaps not, might kill them.

Pretty much so. There were men placed on testosterone for health reasons. I knew a few. They were overweight middle age guys with unhappy wives. Of course, nothing like today.

Maybe, if you’re saying an in shape guy (who participates in a sport) with mid to high normal testosterone is immune from the side effects that an out of shape middle aged lower test guy may claim to experience, I do not know. However, we certainly raised estrogen to high levels and the only ones that seemed to be concerned were they guys in the lower weight classes who generally had to work to keep their weight down. Most trained under the weight limit of their class anyway, knowing full well they would put weight on and that a good part of that was fluid retention.

I don’t think anyone was talking about crashing E2. It is some of the side effects of elevated E2 that are questioned. For the most part, we just did not see them.

I think this is reasonable, but also the exception. I’m not saying high E2 is never a problem, just over exaggerated here.

Another maybe. Sure, they may not get the maximum benefit, but there are guys who continue to eat like crap and sit around all day that have done very well on TRT.

That’s one way to go, I suppose. Hope she was finished.

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I was on gel starting in January for a few months. I was fine on 1 pump then 2. Then went to 3 and all the sudden anxiety. It was my first time on trt. 6 months later started cypionate last thursday. First week felt great. Not sure if its in my head or what but i definitely feel like i have more energy already. Workouts this week were great like they were 5 years ago. No anxiety at all.

This is not always the case, lean muscular men can aromatase like crazy. No two men will aromatize the same and body fat isn’t the only driving factor, the amount of aromatase enzymes in the fat tissue and so you can have low body fat and high aromatization.

We haven’t even considered androgen receptor sensitivity, a low sensitivity would produce less symptoms at higher levels and someone with high sensitivity would have symptoms at modest levels.

There is a reason why a guy like me can get away with lower levels. You’re stuck on levels alone and unable to see the larger picture.

@dbossa @highpull @bmbrady77

Look at every single person that has real issues with E2. They almost all have SHBG of less than 25. The folks over 30 are the ones that end up letting E2 ride and turn out fine or better than before. These are the same folks that can take higher doses without issues. The low SHBG guys can barely do 100mg without acting like they are on the verge of overdosing. It’s total speculation but everyone with these issues here always posts labs showing low SHBG. There has to be something to it. I would bet low SHBG is a very very small portion of people on TRT but make up a majority of those that have issues on it (a large portion of people on forums). Hell most of what I attributed to issues with TRT ended up being anemia. My SHBG is 40.

To sum it up:
So for a majority of folks on TRT they can have estrogen overflowing out of their ears and be fine but for the small group of low SHBG guys (large online presence) they will need a separate program to achieve similar results. Maybe this is proved wrong but I see it often.

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Very well said dexter.

My shbg is lowish, between 19-26 or so depending on protocol.

As soon as my E2 gets up over about 50 on a sensitive test, boners start to fail even with pde5s. Libido is no where to be found either.

Strength is good though at the gym.

On more spread out protocols, my E2 is lower. I THINK it’s because the infrequency of shots lets my body clear out E2, while maintaining a high enough FT with the larger shot. And therefore, I get better results with less Free E2 floating around.

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You guys make me laugh. Keep chasing this E2 numbers since it is such a scary thing. You’ll never get it. Everyone I know doesn’t do that and are all doing way better than before, including me! Please see if you can find any literature that demonstrates why you should be afraid of it? I know I keep repeating myself but nobody has answered this question.

By the way, my protocol is 250-300mg a week, SHBG is 18…E2 is over 60. Meanwhile, couldn’t be better if I tried.

Be afraid! Be very afraid lol! I spent three years trying to control estrogen. What a waste of time. I guess you guys have a ton of free time on your hands!

I’ve said this a hundred times, and I’ll say it again because there is still one aspect of this that YOU can’t seem to get…

I’m in agreement with you and am currently doing 26mg ED, and no AI, and have NEVER taken an AI, and am seeing where this goes. My SHBG is 13.3 right now lol!

BUT…you will never throw enough statistical evidence and/ or success stories in a hundred lifetimes that will carry more weight with these guys than their OWN PERSONAL EXPERIENCES. They (some not all) have tried the “let it ride” approach. For some of them, I’m sorry to tell you sir, it just DOESN’T WORK!

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I will give anyone here $1,000 in cash if they get seen by a legitimate doctor like dr. Nichols and don’t feel a million times better on his protocol without blocking estrogen. I haven’t found one of those guys so far. There’s not just him. There are lots of doctors that know how to do this stuff properly. If you guys want to make generalizations based on personal experiences be my guest. If it didn’t work for you, you were doing something wrong, I absolutely guarantee it.

I hit an E2 (LC/MS/MS) of 71 with SHBG of 19 with once weekly 200mg. Felt great.

Send me $1000

I’ve been on his suggested 30mg a day for over 5 weeks now.

Nothing but shitty boners.

Yeah… All you have to do is take 30mg a day and that’s it. He’s paid to tell you to do that.

Seriously? If that’s all it took I’d be rich.

Give it more time. 5 weeks isn’t enough. Get labs in the next 2-3 weeks and show what your free T is.

@roscoe88
We go over this every week so this is the one for week 5. You need 6-8 weeks. Right now you are in your car on the way to the restaurant. You can’t post a yelp review of the restaurant before you get there. I mean you can but you shouldn’t.

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Yeah yeah…

Sorry for the pessimism.

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We’ve all been there.

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Best advice I can possibly give you:

When you have an issue, pretend E2 doesn’t exist. This will allow you to find the CORRECT answer as to what is ACTUALLY wrong. If you focus on E2, or even keep it as a variable, you will never figure things out.

I’m about half way through, but you have to like this guy. I would definitely prefer a doctor who walks the talk and takes his own medicine. If he does switch to scrotal cream it will be interesting to get his thoughts. Guys I’ve talked to have no interest in cream, doing well with an injection and prefer the convenience of one injection a week. Nice that options are available.

They prescribed me 18g to draw and 22g to inject. And told me pin inner thigh. Theres gota be a better place. This shit hurts like a Mfer. Cant squat down let alone squat weights for 3-4 days after. I have 29g 1/2” that i bought on amazon but that was if i decided to switch to daily. Since im staying weekly for now what should i use thats relatively quick and less painful 25g or 27g . Should i switch to outer quad? These charlie horses suck.

You know it almost sounds like your doc is trying to make this the most miserable experience you could possibly have so you will not want to do TRT.

Get a 25 or 27 and for God’s sake pin on your OUTTER quad!!

Please tell me you didn’t do that. Are you sure that is what they said? Switch to outer upper glute or outer thigh.

I wish the hell i hadn’t. It was some nurse aid or whatever would work in a urologist under a nurse practitioner. I questioned it she showed me where. I did it. It didn’t hurt or bleed at all until later that night. It hurt bad. I did it again today my second shot and it bled pretty good and hurts about the same so i started reading and watching videos and not a single one says inner thigh. And i kinda knew the 22g was ridiculous. Do i need 1.5” or can i go shorter for outer quad