One More TRT Thread

tomorrow starts my first injection of t-cyp 200mg every four weeks
now i am not a doctor! and dont even pretend to completely understand all that is happening in a a males axis but i am very good at finding out info when in need “most of the time” now from all of the threads i have read …um every four weeks? this goes against what i have read as a good protocol. and i can find plenty of seemingly intelligent post about the roller coaster effect.

i need some more technical references to bring him that are not limited to Dr chrisler or associated with forum talk

well heres the lab reports ill post the out of range reports
for now and add any later that might be of concern


age 32
weight165- 170
bf % 16-20
dietary habits are on point training is 4+ days a wk


cholesterol total L 112 125-200

hdl L 35 > or =40

prolactin L1.4 2.0-18.0

t-total L199 250-1100

t-free percent H 2.96 1.5-2.2


If i have missed this topic in my searches and it has been covered, my applogy as admitably i have not had the time to properly search all of my recent concerns

The T-cyp package insert states:

“For replacement in the hypogonadal male, 50-400mg should be administered every two to four weeks.”

That is where the problem starts. That is a very old dosing guide that (1) predates acceptance of self injections [thus avoiding having the patient present at the office too often], (2) package inserts are FDA approved, there is no motivation to start this all over again with the FDA. This package insert is used for many brands of Test cyp.

Tell your doc that HRT is not a huge spike of T, followed by weeks of decline with very very low levels. The spike of T will cause a spike in E2, the increase in E2 will carry over past the decline of testosterone and create an adverse T:E2 ratio.

The increased E2 will cause the liver to produce more SHBG. The increased SHBG will reduce the t-free percentage. At the end of 2,3 o4 four weeks, FT can be lower than before the start of TRT and combined with E2 side effects, guys can end up feeling worse than before starting TRT.

HRT needs to recreate the hormone levels of youth. That should be true every day. Huge spike of T followed by crashed T levels is simply not going to produce very good results.

This is now so obvious, I don’t know if there are going to be research findings to support this.

Women to not get a single dose of HRT per month.

Young and normal males do not have mostly steady hormone levels.

Make your own argument for this. If he will not listen to things like this that you state, you will never get where you need to be with this doc. Such as T+AI+hCG.

While this speaks to some issues:
http://ajpendo.physiology.org/cgi/content/full/281/6/E1172

It does not recommend weekly or any other dosing, but weekly dosing was used in this study.

Note that the serum levels were tested after one week. Good practice is to check these levels 1/2 between injections to get something closer to an average level.

Also point out that all transdermals attempt to create the same T levels every day.

Tell the doctor that you want to self inject to take the issue of convenience vs office visits off the table and that you want to inject once or twice a week to maintain a more natural HRT.

He will listen, or ignore you, perhaps letting his ego get in the way. Know that you may need to find another doctor.

thanks ive got the ok to do self injects so i know that i could do it as i want, but i want to bring him on board as to what i am doing he seems pretty cool and i dont want to piss him off

found this one

https://www.T-Nation.com/tmagnum/readTopic.do?id=1383172&pageNo=0

e-loo provided this good link in this thread
need another one or two anybody

Hey Hangiron,

In my opinion the shot you are getting will put you on a freakin roller coaster. I get the same dosage you do but every 8 days. I would go back to your doctor and discuss this with him. There is some great articles out there and I will send you the links if you want them. A good reference is Dr John Crisler, he is an expert on this subject. The dosage your doctor is prescribing is very old school and I would not want.

Take care, guiman

all references accepted. i posted maybe not clearly. as i should of stated those links for Dr Crisler are everywhere. in every anabolic this or muscle that forum! they are great reads no doubt, but i am interested in multiple references
thanks