TSH should be closer to 1.0
fT3, fT4 should be near mid-range or a bit higher.
fT3, fT4 are stating that you are hyper
TSH says you are hypo
Suspect that you have elevated rT3 blocking fT3. Check your oral body temperatures, see below, to evaluate your overall thyroid function and post temperatures. Also discuss your history of using iodized salt. If low, see references to rT3, stress, adrenal fatigue and Wilson’s book in the thyroid basics sticky.
Thyroid lab ranges are stupid. Do not expect your doctor to understand any of that.
You need to be near E2=22pg/ml and your E2=45.2 is horrible and also a libido killer that probably makes you moody and intolerant.
Most guys need 1mg anastrozole for every 100mg T ester. We can also calculate a new dose from labs if your dosing prior to lab was consistent. New dose = old dose x 74.5/80 where the target is 22pg/ml or 80 pmol/L. So your adex dose for the 2nd set of labs is fine, IF you were dosing consistently for 8 days prior to your labs.
Thyroid problems easily kill libido.
You need to test AM Cortisol, at 8AM or 1 hour after waking up to see if low progesterone might be causing lower progesterone–>cortisol in the adrenals. If you have adrenal fatigue, multiple adrenal hormones affected. DHEA is also an adrenal hormone, but DHEA it at a lifetime high at your age. The lab test would be DHEA-S, not DHEA.
Were prolactin, LH and FSH tested before you started TRT. Malpractice otherwise. Post these.
You can find “KAL” brand progesterone cream at Amazon.com [USA].
Elevated prolactin can cause low LH, FSH, T and dopamine, the latter can contribute to depression and lack of joy/satisfaction. Typical cause is a prolactin secreting pituitary adinoma and treatment to shrink and maintain is 0.5mg cabergoline per week. If you take that, MRI to visualize may fail.
Pregnenolone is made in mitochondria in every cell in your body with the testes been particularly active and with hCG that should be supported.
Training with thyroid problems and low-T typically in young guys is fueled with adrenalin taking over for lost natural energy, then there are cortisol disturbances, adrenal issues, increased rT3 - see references above.
What is anastrozole dosing for 2nd labs?
Please read the stickies found here: About the T Replacement Category - #2 by KSman
- advice for new guys - need more info about you
- things that damage your hormones
- protocol for injections
- finding a TRT doc
Evaluate your overall thyroid function by checking oral body temperatures as per the thyroid basics sticky. Thyroid hormone fT3 is what gets the job done and it regulates mitochondrial activity, the source of ATP which is the universal currency of cellular energy. This is part of the body’s temperature control loop. This can get messed up if you are iodine deficient. In many countries, you need to be using iodized salt. Other countries add iodine to dairy or bread.
KSman is simply a regular member on this site. Nothing more other than highly active.
I can be a bit abrupt in my replies and recommendations. I have a lot of ground to cover as this forum has become much more active in the last two years. I can’t follow threads that go deep over time. You need to respond to all of my points and requests as soon as possible before you fall off of my radar. The worse problems are guys who ignore issues re thyroid, body temperatures, history of iodized salt. Please do not piss people off saying that lab results are normal, we need lab number and ranges.
The value that you get out of this process and forum depends on your effort and performance. The bulk of your learning is reading/studying the suggested stickies.