Actually it directly applies to Ivan, because it can lead to a pro-inflamatory condition, and hinder his results.
[quote]Enter the other antioxidant big boy, vitamin C. As another vitamin with a history of low-toxicity and a correspondingly high “tolerable upper limit” of 2000mg per day, thereâ??s nothing wrong with supplementing a gram or two every day, right? Heck, itâ??s even water-soluble and therefore more easily excreted.
Unfortunately, thereâ??s more to it. Vitamin C supplementation (500mg for six weeks) has been shown to actually induce pro-oxidant effects in healthy humans, as measured by DNA damage. (31) Very high doses (500mg/kg) in rats cause superoxide radical generation, induce P450 liver enzymes (particularly risky to even moderate drinkers) and, again, DNA damage. (29, 31)…[/quote]
Dr. Lonnie Lowery does present is this article what he calls “The Cyclical Use Theory,” which seems novel, but states that there are better ways to reduce cortisol than to take 1,500 mg of Vit C.
Sorry but I can’t happen to find the study that directly shows a correlation between Vit C supplementation and decreased Muscle Protein Synthesis, but one study I can share researchers have found that interfering with free radical metabolism by taking antioxidants may hamper useful adaptations to training and that exercise itself can be considered an antioxidant.
The researchers conclude[quote] “In all likelihood, antioxidant supplements should not be recommended before training as they interfere with muscle cell adaptation”[/quote]
Further, ROS act as signals in exercise because decreasing their formation prevents activation of important signaling pathways that cause useful adaptations in cells. Because these signals result in an upregulation of powerful antioxidant enzymes, exercise itself can be considered an antioxidant.
Physical exercise is a double-edged sword: when practiced strenuously (as in the case of the tour de france) it causes oxidative stress and cell damage; the study says that in this case antioxidants should be given. But when practiced in moderation (of which the definition is not given in the study), it increases the expression of antioxidant enzymes and thus should be considered an antioxidant.
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