No L-Glutamine With Adderall?

Diet and Nutrition
21 
 Adderall does more than help your attention span. I started talking it in my late-30s it has helped with my decision making ability, organizational skills, and staying on tract with tasks. I hate to sound like a Harley owner "If you haven't driven one I can't explain it to you" but it's true.

I’ve talked to people who took it for recreational or studying purposes and they all report a racing heart beat, jitters, insomnia, etc. all the thing you’ve come to expect from “speed”. My physical reaction is nothing, my HR and BP don’t go up at all, I look and act perfectly normal. I’m back in school on the Deans List, prior semesters I was on academic probation twice.

Is it over prescribed? -YES- their are some kids that would be better with a change in diet and instruction in Zen Meditation -BUT- a chemical is needed for some people. I could go off it and back to a job that doesn’t need a normal focus but I would rather take a pay cut for a few years and study to do something I’ve always wanted to do but didn’t think I was smart enough to do.

When another medication comes around that will be as effective with less sides (Modafinil anyone?) I’ll switch but for now I have to take what works.
Phileaux
P.S. No, I haven’t hear of any counter interactions with L-glut.

22

[quote]Phileaux wrote:
Adderall does more than help your attention span. I started talking it in my late-30s it has helped with my decision making ability, organizational skills, and staying on tract with tasks. I hate to sound like a Harley owner “If you haven’t driven one I can’t explain it to you” but it’s true.

I’ve talked to people who took it for recreational or studying purposes and they all report a racing heart beat, jitters, insomnia, etc. all the thing you’ve come to expect from “speed”. My physical reaction is nothing, my HR and BP don’t go up at all, I look and act perfectly normal. I’m back in school on the Deans List, prior semesters I was on academic probation twice.

Is it over prescribed? -YES- their are some kids that would be better with a change in diet and instruction in Zen Meditation -BUT- a chemical is needed for some people. I could go off it and back to a job that doesn’t need a normal focus but I would rather take a pay cut for a few years and study to do something I’ve always wanted to do but didn’t think I was smart enough to do.

When another medication comes around that will be as effective with less sides (Modafinil anyone?) I’ll switch but for now I have to take what works.
Phileaux
P.S. No, I haven’t hear of any counter interactions with L-glut. [/quote]

Good post. If you take it late in the evening then obviously you will have a hard time getting to sleep. Take it in the morning and lunch and at the latest 3:00 p.m.

Also, take it AS PRESCRIBED by your doctor.

My EKG or ECG (what they call it nowadays) showed that I have an athletic heart, which is a GOOD thing. This probably do to running track in highschool and working out a lot.

I’m prescribed 10mg 3 times a day. I break them in half and take 5mg 4 times a day.

I have also talked to a NEUROLOGIST (who is a member of my family) and asked about the long term effects of taking adderall. He said that their are no bad effects of taking it long term.

Ruin your heart? I am still waiting for the evidence beebuddy…

23

From what I’ve researched, the only people that had problems with Adderall were one’s that already had a congenital heart defect or heart problem. If you have a healthy heart to begin with you’ll be fine. Adderall does not cause heart defects.

You have to remember to that the occurance rate was 20 deaths in 30 million prescriptions over a 4 year span from 1999 to 2003. The odds of getting killed by lightning is 1 in 2,320,000, which is pretty close.

You have to weigh the positives against the negatives. Is getting A’s in class compared to C’s, getting a better job, and having higher self-esteem worth the chance of being killed by lightning? Only you can decide.

24

[quote]Bri Hildebrandt wrote:
From what I’ve researched, the only people that had problems with Adderall were one’s that already had a congenital heart defect or heart problem. If you have a healthy heart to begin with you’ll be fine. Adderall does not cause heart defects.

You have to remember to that the occurance rate was 20 deaths in 30 million prescriptions over a 4 year span from 1999 to 2003. The odds of getting killed by lightning is 1 in 2,320,000, which is pretty close.

You have to weigh the positives against the negatives. Is getting A’s in class compared to C’s, getting a better job, and having higher self-esteem worth the chance of being killed by lightning? Only you can decide.
[/quote]

I’ll settle for B’s, occasional C’s and my own personality over straight A’s and a borderline neurotic mindset after a few days of continuous use personally.

I don’t disagree the stuff is helpful, but it is a hell of a pill to take.

If you do get on it, do not forget a dose if you go out of town, spend the day away from home/office etc. You will have a headache from hell, feel sluggish all day and will have trouble sleeping that night. The following day, even if you take a dose you will still feel weird and just kind of off.

And do be careful training with it. I’m in pretty good shape, strength and cardio, and as you can read in my earlier post, it through me for a loop.

See if you can get friends with a prescription to give you a few pills before studying for tests and what not and use it for studying every now and then. You’ll get all the benefit with temporary and limited side effects. Don’t pull an all nighter. Study for a few hours a day starting a few days before your test and let the adderall give you your focus during your normal study time.

It’s definately not a magic pill to increase your IQ, but once you start studying, you’ll get lost in your books and before you know it, five hours have gone by and you’ve studied more than you had in the past three years collectively.

25

[quote]Bri Hildebrandt wrote:
From what I’ve researched, the only people that had problems with Adderall were one’s that already had a congenital heart defect or heart problem. If you have a healthy heart to begin with you’ll be fine. Adderall does not cause heart defects.

You have to remember to that the occurance rate was 20 deaths in 30 million prescriptions over a 4 year span from 1999 to 2003. The odds of getting killed by lightning is 1 in 2,320,000, which is pretty close.

You have to weigh the positives against the negatives. Is getting A’s in class compared to C’s, getting a better job, and having higher self-esteem worth the chance of being killed by lightning? Only you can decide.
[/quote]

You are talking about acute heart problems. I am talking about burning out the heart muscle over time. Some people believe that your heart only gets so many beats per lifetime and people who exercise regularly and have a lower resting heart rate, tend to live longer. It could be causative, it could be a mere correlation… It’s just an idea, but it’s an idea that makes sense.

Amphetamine speeds up your heart rate a lot. It hasn’t been prescribed long enough to have any research on the long term effects. Its Russian roulette if you ask me.

26

[quote]Amphetamine speeds up your heart rate a lot. It hasn’t been prescribed long enough to have any research on the long term effects. Its Russian roulette if you ask me.

[/quote]

It HAS been prescribed since the 70’s. How old are you and why do you keep insisting on what speeds up your heart will ruin your heart.

Doesn’t cardio speed up your heart rate? That’s a rhetorical question.

27

My prescriptive Adderall XR is a combination of Amphetamine and Dextroamphetamine, fast and slow acting. My resting HR is in the low 60’s when I wake up, after taking my meds and walking around it jumps to the low 70’s!!! Is this the racing HR that you are describing???
Concerning prescribed amphetamine, it was given/available to pilots during WWII to keep them up during long overseas flights. I’m sure their was abuse (any drug) but you would have to check their med records to see if their was any damage.

Phileaux

28

[quote]texasguy1 wrote:
I’ll settle for B’s, occasional C’s and my own personality over straight A’s and a borderline neurotic mindset after a few days of continuous use personally.

I don’t disagree the stuff is helpful, but it is a hell of a pill to take.

If you do get on it, do not forget a dose if you go out of town, spend the day away from home/office etc. You will have a headache from hell, feel sluggish all day and will have trouble sleeping that night. The following day, even if you take a dose you will still feel weird and just kind of off.

And do be careful training with it. I’m in pretty good shape, strength and cardio, and as you can read in my earlier post, it through me for a loop.

See if you can get friends with a prescription to give you a few pills before studying for tests and what not and use it for studying every now and then. You’ll get all the benefit with temporary and limited side effects. Don’t pull an all nighter. Study for a few hours a day starting a few days before your test and let the adderall give you your focus during your normal study time.

It’s definately not a magic pill to increase your IQ, but once you start studying, you’ll get lost in your books and before you know it, five hours have gone by and you’ve studied more than you had in the past three years collectively. [/quote]

What I said applies to people with ADD/ADHD, not the general population.

29

[quote]VALERIUS wrote:
It HAS been prescribed since the 70’s. How old are you and why do you keep insisting on what speeds up your heart will ruin your heart.

Doesn’t cardio speed up your heart rate? That’s a rhetorical question.[/quote]

Why are you asking irrelevant personal questions that have nothing to do with the value of the words on the screen? Also, can you not read? The reasoning behind every statement was provided, and there is no interest in whether or not you agree with that reasoning.

The cardio example is stupid. Cardio, unlike amphetamine, ultimately lowers resting heart rate.

Debating whether amphetamine is healthy or not is ludicrous.

30

[quote]beebuddy wrote:
You are talking about acute heart problems. I am talking about burning out the heart muscle over time. Some people believe that your heart only gets so many beats per lifetime and people who exercise regularly and have a lower resting heart rate, tend to live longer. It could be causative, it could be a mere correlation… It’s just an idea, but it’s an idea that makes sense.

Amphetamine speeds up your heart rate a lot. It hasn’t been prescribed long enough to have any research on the long term effects. Its Russian roulette if you ask me.

[/quote]

Amphetamine was invented in 1887. How much more research do you need?

31

[quote]beebuddy wrote:
VALERIUS wrote:
It HAS been prescribed since the 70’s. How old are you and why do you keep insisting on what speeds up your heart will ruin your heart.

Doesn’t cardio speed up your heart rate? That’s a rhetorical question.

Why are you asking irrelevant personal questions that have nothing to do with the value of the words on the screen? Also, can you not read? The reasoning behind every statement was provided, and there is no interest in whether or not you agree with that reasoning.

The cardio example is stupid. Cardio, unlike amphetamine, ultimately lowers resting heart rate.

Debating whether amphetamine is healthy or not is ludicrous. [/quote]

cardiac output = heart rate x stroke volume (CO = HR x SV)

changes in either heart rate or stroke volume will have an impact on the other component.

For an untrained person who has a resting heart rate of 72 beats/min and a stroke volume of 70 ml, the resting cardiac output is calculated as follows:
Cardiac output = Heart rate x Stroke
Cardiac output = 72 x 70
Cardiac output = 5040 ml/min
Cardiac output = 5.04 L/min
(NOTE: 1000 ml = 1 L)

During the initial stages of exercise, increased cardiac output is due to an increase in both heart rate and stroke volume. When the level of exercise exceeds 40% to 60% of the individual’s capacity, stroke volume has either plateaued or begun to increase at a much slower rate. Thus further increases in cardiac output are largely the result of increases in heart rate.

How your body responds to aerobic exercise
During aerobic exercise, you repeatedly move large muscles in your arms, legs and hips. You’ll notice your body’s responses quickly.

You’ll breathe faster and more deeply. This maximizes the amount of oxygen in your blood. Your heart will beat faster, which increases blood flow to your muscles and back to your lungs. Your small blood vessels (capillaries) will widen to deliver more oxygen to your muscles and carry away waste products, such as carbon dioxide and lactic acid. Your body will even release endorphins, natural painkillers that promote an increased sense of well-being.

Regular aerobic exercise can:
Strengthen your heart. A stronger heart doesn’t need to beat as fast. A stronger heart also pumps blood more efficiently, which improves blood flow to all parts of your body.

Which is exactly why I do NOT have to worry about ADDERALL RUINING my HEART.

32

[quote]Bri Hildebrandt wrote:
texasguy1 wrote:
I’ll settle for B’s, occasional C’s and my own personality over straight A’s and a borderline neurotic mindset after a few days of continuous use personally.

I don’t disagree the stuff is helpful, but it is a hell of a pill to take.

If you do get on it, do not forget a dose if you go out of town, spend the day away from home/office etc. You will have a headache from hell, feel sluggish all day and will have trouble sleeping that night. The following day, even if you take a dose you will still feel weird and just kind of off.

And do be careful training with it. I’m in pretty good shape, strength and cardio, and as you can read in my earlier post, it through me for a loop.

See if you can get friends with a prescription to give you a few pills before studying for tests and what not and use it for studying every now and then. You’ll get all the benefit with temporary and limited side effects. Don’t pull an all nighter. Study for a few hours a day starting a few days before your test and let the adderall give you your focus during your normal study time.

It’s definately not a magic pill to increase your IQ, but once you start studying, you’ll get lost in your books and before you know it, five hours have gone by and you’ve studied more than you had in the past three years collectively.

What I said applies to people with ADD/ADHD, not the general population.[/quote]

Me too. According to the Doc, I do have ADHD.

33

[quote]beebuddy wrote:

Amphetamine speeds up your heart rate a lot. It hasn’t been prescribed long enough to have any research on the long term effects. Its Russian roulette if you ask me.

[/quote]

They do to a certain extent especially in cases of abuse. Most prescribed doses though are not high enough to continuously cause this effect. At first one might experience an excellerated heart rate along with euphoria but after a few days or weeks your body adapts with the increased tolerance. It didn’t take long for this to happen to me when I was on it. I could actually take a dose and fall asleep a half hour later.

Unfortunately after a short period of time I noticed no improvement on focus. So I went off. I think its only good if it stimulates you. Something thats hard to keep up without increasing the dose till you live in a shitty trailer park and your officially a tweaker.

34

[quote]texasguy1 wrote:
Bri Hildebrandt wrote:
texasguy1 wrote:
I’ll settle for B’s, occasional C’s and my own personality over straight A’s and a borderline neurotic mindset after a few days of continuous use personally.

I don’t disagree the stuff is helpful, but it is a hell of a pill to take.

If you do get on it, do not forget a dose if you go out of town, spend the day away from home/office etc. You will have a headache from hell, feel sluggish all day and will have trouble sleeping that night. The following day, even if you take a dose you will still feel weird and just kind of off.

And do be careful training with it. I’m in pretty good shape, strength and cardio, and as you can read in my earlier post, it through me for a loop.

See if you can get friends with a prescription to give you a few pills before studying for tests and what not and use it for studying every now and then. You’ll get all the benefit with temporary and limited side effects. Don’t pull an all nighter. Study for a few hours a day starting a few days before your test and let the adderall give you your focus during your normal study time.

It’s definately not a magic pill to increase your IQ, but once you start studying, you’ll get lost in your books and before you know it, five hours have gone by and you’ve studied more than you had in the past three years collectively.

What I said applies to people with ADD/ADHD, not the general population.

Me too. According to the Doc, I do have ADHD. [/quote]

Ok, cool.

35

Look people, the proof of the existence and major impact of ADD has been in the bag for years and years now. I’ve always been amazed by all the strong anti-ADD sentiment from people who don’t even know what they are talking about.

I don’t have ADD but I know people who do. Be grateful you don’t have it – it can be a severe handicap that affects and stands in the way of people in everything they do.

Look at PET scan studies of people with ADD. Their brains have very distinct signatures. Sure it may be overdiagnosed but it’s also underdiagnosed and people who don’t know what they are talking about going around spewing uninformed and prejudiced opinions on ADD aren’t helping anyone with.

The only thing that’s going to get the right people treated and the wrong people not, is clarity of information.

36

[quote]2ms wrote:
Look people, the proof of the existence and major impact of ADD has been in the bag for years and years now. I’ve always been amazed by all the strong anti-ADD sentiment from people who don’t even know what they are talking about.

I don’t have ADD but I know people who do. Be grateful you don’t have it – it can be a severe handicap that affects and stands in the way of people in everything they do.

Look at PET scan studies of people with ADD. Their brains have very distinct signatures. Sure it may be overdiagnosed but it’s also underdiagnosed and people who don’t know what they are talking about going around spewing uninformed and prejudiced opinions on ADD aren’t helping anyone with.

The only thing that’s going to get the right people treated and the wrong people not, is clarity of information.[/quote]

Good post.

I have been on the same dose for years now and never had to up the dose. It’s called personal responsibility. If you choose to abuse adderall, then adderall will abuse you. I must be supernatural, because after several years of using adderall for ADD, my EKG showed that I have a healthy heart.

I think some people don’t want to admit their mistakes on abusing medication, or admit that THEIR poor lifestyle choices caused the problem.

37

THIS IS WHY NOT TO COMBINE GLUTAMINE AND ADDERALL (assuming that when you take large amounts of glutamine supplements that it is able to effectively cross the BBB in relevant amounts):

Effects of amphetamine on the release of excitatory amino acid neurotransmitters in the basal ganglia of the conscious rat.
Mora F, Porras A.

Department of Human Physiology, Faculty of Medicine, University Complutense of Madrid, Spain.

The effects of systemic injections of amphetamine sulfate on the release of aspartic acid, glutamic acid, and glutamine were studied using a push-pull perfusion system in the conscious rat. Amphetamine produced a dose-related increase of the extracellular levels of aspartic acid and glutamic acid. The mean time effect of amphetamine was 40 min, followed by a recovery to baseline levels.

The mean percentage increase in amino acids released by the highest dose of amphetamine (5 mg/kg) was as follows: Asp, 334.6%; Glu, 224.5%; and Gln, 317.6%. All these effects were blocked by the dopamine D1-D2 receptor blocker haloperidol. It is suggested that dopamine, released by amphetamine, induces the release of amino acid neurotransmitters in the neostriatum. In addition, it is proposed that dopamine could mediate the neurotoxic effects produced by amphetamines through their secondary action on the release of excitatory amino acids.

Amphetamine increases extracellular concentrations of glutamate in the prefrontal cortex of the awake rat: a microdialysis study.
Del Arco A, Martínez R, Mora F.

Department of Physiology, Faculty of Medicine, Universidad Complutense, Ciudad Universitaria, Madrid, Spain.

Using microdialysis, the effect was investigated of intracerebral infusions of different doses of amphetamine (1.25, 2.5, 5, 10, and 20 microg/microl) on the extracellular concentrations of glutamate in the medial prefrontal cortex of the rat. Amphetamine produced a dose-related increase in extracellular concentrations of glutamate. At the highest dose, amphetamine increased extracellular glutamate by 445% of baseline as well as extracellular concentrations of taurine, and reduced extracellular concentrations of glutamine.

Amphetamine did not modify other amino acids such as arginine. Increases in extracellular concentrations of glutamate and taurine were independent of calcium in the perfusion medium. This is the first study showing that amphetamine produces a calcium-independent increase in extracellular concentrations of glutamate and taurine in the medial prefrontal cortex of the rat.

38

I will respond to these last postings after I eat my breakfast.