The development and maintenance of the seminal vesicles, as well as their secretion and size/weight, are highly dependent on androgens.[8][9] The seminal vesicles contain 5α-reductase, which metabolizes testosterone into its much more potent metabolite, dihydrotestosterone (DHT).[9] The seminal vesicles have also been found to contain luteinizing hormone receptors, and hence may also be regulated by the ligand of this receptor, luteinizing hormone.[9]
I find it interesting that in doing research on seminal vesicles I find that 80 to 90% of our ejaculate come from them and it says that the seminal vesicles have lh receptors. I wonder if some of this issue is the lack of lh?
Dunno man because when I cut my T does within a week Im back to a full load.
I think you are on to something here. This is from PubMed, “In summary, DHt appears to regulate semen volume and viscosity through its action on the development and function of the prostate and seminal vesicles.” But what part are we missing?
Edit: I also keep reading that 5-alpha reductase inhibitors can reduce ejaculate volume. Ive never taken one but interesting.
Helps in development to me seems like puberty and growing. Once in place and fully matured dht can inhibit the effects. I was running masteron which is a dht derivative. I wonder if that exaggerates the issue at all.
So too much conversion to DHT may be the culprit?
Possibly to much conversion to dht and lack of lh production for activation of lh receptors in the seminal vesicles
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So I dropped my dose from 70mg x 2 weekly to 60mg x2 weekly starting on Monday and second dose was today. Like clockwork I got a few zits on shoulders, back, and ass and also my ejaculate volume came back to normal. Would still love an answer on this @yeti308 (et al). I feel better with dose closer to 140mg a week.
I’m going through the same issues right now. Went from 250 mg twice a week and the did an injection of 100 mg on Monday and yesterday did 50 mg. Back is breaking out. Ejaculate volume is way way up. Libido is even better as well. A bit of a hair trigger.
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Yes, me too, on the libido thing as well. I was good to go before but now a bit voracious.
@NH_Watts - How long did it take you to get your most recent blood work results back from Ulta?
Appointment was Friday May 31st and I had my results on Tuesday June 4th.
Thank you. Had my appointment Tuesday and have most results back. I have hematocrit, hemaglobin, prolactin and sensitive E2. Still waiting for all test values. Hoping they come soon.
Thanks again
@NH_Watts - have you ever seen “N/A” in the test results? It said “Pending” until last night, now “N/A”.
Is this the Quest page or the Ulta page? I know I got the Ulta info first. I don’t remember seeing the N/A before, no.
Ulta page, sorry.
I guess I’ll have to call to see what that means. Kinda bummed out the first time I try them, I see this. Oh well.
Side note, I’m doing 140mg/week too (40mg EOD). I’m interested to see where my test numbers come out.
Last time I got SHBG tested, I was 16:8 IF every day and it was 38. I’m not IF any more and SHBG dropped to 27!
Thanks again
@NH_Watts - Guess I just had to be patient. These numbers are so much higher than what I get when I’m tested in the doctors office. Last Total test reading I had in office was 601… This is bananas.
At what point between shots was the draw?
I guess you are EOD so no real trough day. Were you EOD before when you had your draw?
Yah boy go ride that’s fun and great for cardio and losing fat. Just ride at 70-80% of max for a good amount of time for maximum benefit.