I can tell you this from my research. Most people, including type 1s in the first few years will have their liver put out glucose to help stop low blood sugar caused by too much insulin/activity. The hormone that causes the glucose to be put out is glucagon. It is put out by the alpha cells of the pancreas, cells that don’t get destroyed by the autoimmune attack. Unfortunately when the beta cells that put out insulin and amylin are gone, the alpha cells start to act dysfunctionally. They will spit out glucagon and raise blood sugar when you eat even before the carbs from the food hits your bloodstream. They will even spit out glucagon if you eat low calorie large mass vegetable matter like a lot of lettuce. The second problem is that you no longer have amylin to tell the stomach to delay emtpying its contents and also to tell the liver not to release stored glucose from glycogen. The third problem is that the pancreas STOPS working to release glucagon when you get low blood sugar, so after about 5 years most type 1s loose the ability to have their liver help in a controlled way to bring up blood sugar when needed. It is believed that this may be a neuropathy of the alpha cells caused by high blood sugar (so good control can help you keep this ability longer, and therefore keep good control longer). It COULD be that the disfunction is due to the pancreas not having self made insulin, and so it gets out of whack in knowing how much glucagon to make or when to release it because the insulin levels in the body help regulation.