I’m about 20wks in. Been injecting 125mg/test cyp twice a week(total of 250mg/week).
No AI and no HCG.
Will be getting labs drawn soon.
I am curious to know if anyone has experience with lowering dosage of T to manage E2 levels. If so, how long will it take for things to level off?
If you are having issues at 20wks then you’re ready for a dosage change. What’s your E2 and what are your issues?
It will take 6-8 weeks for levels to balance out after a dosage change.
I’ll know my numbers after I get labs.
Felling blah, low drive and libito. Was doing good but, all started around 8wks
T and E2 go hand in hand, when T goes down between peak (12-24h after injection) and the next injection E2 will follow. T is the determining factor for E2.
2x 125 mg is a high dose and I wouldnt be surprised if your trough total T is well above 1000 ng/dl and your E2 is around 50-70 pg/ml.
I agree with @dextermorgan its maybe time to change the dose. It will take 4-6 halflifes of your T formulation (3-5 weeks with enant or cyp) to reach stady state levels again.
I’m guessing your total dose is 125/wk, split into 2 shots. If you were good initially and then went downhill, it is probably related to shutdown of your natural production and means that you need a higher dose. Don’t get crazy though, just go up to maybe 150mg and see how that is. A dose change that small won’t actually require 6 week to know how you feel,. I know you will see it posted repeatedly that the world has imploded and you need 6 weeks minimum for it to reset just because you changed your dose. While it is true that your absolute stable number will be adjusting for 6 weeks, the actual change in stable level on a small dosage change like this becomes a miniscule difference after a couple of weeks.
Would this re-adjustment happen with a small dose change too? Let’s say going from 70 mg every 4 days to 65 mg every 4 days?
Any change will cause some readjustment. The question is, will you really notice anything from that? I would say no, not after a few weeks for sure.
He said his total dose is 250mg
Yep, I didn’t see that part in the brackets, or maybe that was one the 2 edits to that post so far? That is a high dose for TRT.
What is with people nowadays taking 250mg a week for TRT? I mean, what kind of doctor is able to get away prescribing this amount?
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@weightliftingwithoutlimits I can tell you and connect you to such doctor. The numbers are not important, its important what dosage do you need to get symptoms resolution and feel good. This is the main purpose of all hormonal treatment
I was advised to start TRT ED 30mg, which is 210mg total but this equals like 250mg if you inject once a week
But who needs 250mg test/week to feel normal? I mean, 250mg per week (stable) is ALOT more than what the average natty produces weekly. if still feels shit at that point then surely the problem is not with test levels per say its obviously something else?
Yes agree. You are setting yourself up to a number of - potentially serious - side effects. Polycythemia and sleep apnea would only be a minor ones. Hepatocellular carcinoma and cardiovascular risks are the more serious ones.
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Because first everybody needs different mg to get his blood levels to number x, and then everybody needs different blood levels of number x to feel OPTIMAL.
I know people who need more than 200mg to get their blood levels to 1200-1300ng/dl. For some other dude 125mg may be enough.
For some people 600 ng/dl total t is enough. For me is not, this is my current natural value and I will start TRT. For some people 1000ng/dl is enough, for some 1500ng/dl is enough. The upper level used to be 1500ng/dl, now some dumb asses say it should be 900. So what is supraphysiological, who decides?
@gp_dude No haha dont look for a good doctor in Bulgaria, you cannot find. I can recommend only US doctors for telemedicine consultation. In Bulgaria the doctors have no idea what is TRT