okay, for you guys that have tried 5-htp, does the delayed orgasm mean a weaker erection? Anyone have experience with this?
come on! I’m 17 yrs old, haha, fill me in on 5-htp, you guys got me lost! Is there anything I can buy OTC to raise my serototin? May be a stupid question, but doesnt serototin give u bitch tits? Like from bein on testosterone too long?
Also, the numbing agent doesnt sound like a bad idea. But I dont know if id be able to keep my wood if i couldnt feel it. I get a wood too man when the wind blows by,only time i can keep it down is at football. But im not sure if it was numb if itd stay up bro.
If my girlfriend sees my rubbin a cream on my dick before hand, i think she might get up and walk out, thinking i got herpes or somethin!
I also have that problem, same as you machine!
My gf get’s really upset if I can’t get off when she goes down on me - she doesn’t think she is pleasuring me… Last time she did it for TWO HOURS, and nothing! She does know what she is doing (it’s great) but it still takes way too long. I’ve tried not jerking for like a week, and then going to see her but it doesn’t change! I don’t know what to do! It just takes fucking forever!
I guess I am just an iron-man of sorts, but it really does get annoying that there can never be a ‘quickie’!
Does anyone have a solution to this? Any way to get off quick???
ARCHAIC: I don`t know for you, but sometimes it depends on the girl.
Lets take for example a blowjob. Because of mouth conformations, no girl is alike, and therefore the feelings you get when you get a blowjob. In some women, it almost feels better than a tight vagina (I say better because of the suction factor, specially when she swallows), in others it is the inverse (and I wont talk about teeth scraping in the process).
Depends also where you are in life. I know it is far harder for me to come than, lets say, 10 years back when a girl does me a handjob - it takes some effort by the girl to get me off that way. On another note, in presence of a hot, wet, tight vagina, I still have to watch myself. I have never tried a loose one so far, and do not wish either – maybe, indeed, then it could take forever, because of lack of adequate friction and so much other sensations
Hope this helps.
If I want a quickie, I just think about how good it feels.
If I don’t want it quick, I don’t think about it. I just hammer away.
2 hours is a long time to get head. You must have a REALLY cool girlfriend.
I still think it’s in the concentration.
Course the female will make a big difference, if they are ugly or non stimulating it requires more concentration to get the job done.
And if they are really really bad then maybe it wont happen.
But in your cases of with gals you are attracted to, I think it’s a mind issue.
What you guys need is a force multiplier. How about some little kids who bang on your bedroom door after 3-5 minutes? That will condition you to get off in that time otherwise you get no chance to do so.
5-HTP is OTC and it does increase serotonin levels. I don’t believe moderate 5-HTP use will cause gyno.
It’s not serotonin that can cause that problem…when you increase serotonin, prolactin also increases. That can theoretically cause gynonecmastia and a milky discharge.
This will most likely not happen at the dosages you need. I would not worry about it. I haven’t seen any complaints on this forum and 5-HTP is in Hot-Rox and was in MD6.
???
you are wrong about 5-HTP EVER being related to gyno…
Probably very, very unprobable to happen but a possibility of breast enlargment due to prolactin increase. Here are some side effects of the Urogenital System listed for the SSRI (Selective SerotoninReuptake Inhibitor)Prozac:
Frequency: urinary frequency; Infrequent: abortion, albuminuria, amenorrhea, anorgasmia, breast enlargement, breast pain, cystitis, dysuria, female lactation, fibrocystic breast, hematuria, leukorrhea, menorrhagia, metorrhagia, nocturia, polyuria, urinary incontinence, urinary retention, urinaryurgency, vaginal hemmorrhagia, Rare: breast engorgement, glycosuria, hypomenorrhea, kidney pain, oliguria, priapism, uterine hemmorrhage, uterine fibroids enlarged.
SSRI’s increase prolactin as does 5-HTP. I think it would have to be an extremely sensitive person and insane dose to ever cause that effect though.
NO, an SSRI is very different from 5-HTP.
5 hydroxytryptophan is a derivative of the amino acid tryptophan which the body converts to the 5-HTP form to cross the blood brain barrier. (which in turn is converted to 5-hydroxytryptamine -aka seratonin)
That would mean that eating bananas (which are high in tryptophan) could give you gyno if you ate too many.
Are you saying that tryptophan can cause gyno?
How much 5htp would you take to delay orgasm?
SSRI’s and 5-HTP work to achieve the same end result through different mechanisms: increased brain serotonin levels. SSRI’s work to inhibit the re-uptake and degradation of serotonin while 5-HTP serves as a precursor molecule. It’s intuitive to think that if SSRI’s can cause gyno, 5-HTP can have the potential to do so, as well.
Just because 5-HTP is an OTC supplement doesn’t mean it isn’t effective. If it crosses the blood-brain barrier, enzymatic conversion to serotonin occurs via decarboxylation. You can draw a parallel with the Parkinson’s drugs Selegiline and L-Dopa. Selegiline selectively inhibits the MAO enzyme that degrades dopamine. L-Dopa is taken orally and is converted to dopamine after crossing the blood-brain barrier. It is often given with the drug Carbidopa, which ihibits the peripheral decarboxylation of L-Dopa to dopamine, thereby increasing the available concentrations of the substrate to enter the brain (dopamine does not readily cross the blood-brain barrier).
Here’s where it gets a little hairy for me: If I remember correctly, dopamine is often referred to as prolactin-inhibiting hormone (PIH). That is why certain anti-psychotic drugs such as Haldol that block dopamine receptors can cause increased prolactin levels. I’m not really sure how serotonin fits in the picture, but if the SSRI’s or 5-HTP somehow alter dopamine levels, it could explain the increased prolactin levels. There could be a variety of mechanisms for this, but I would only be guessing. If anyone has any input on this, please feel free to share. r100proof, can you explain how serotonin increases prolactin? Thanks.
First of all, I was answering a question from Shark stating:
"come on! I’m 17 yrs old, haha, fill me in on 5-htp, you guys got me lost! Is there anything I can buy OTC to raise my serototin? May be a stupid question, but doesnt serototin give u bitch tits? Like from bein on testosterone too long? "
I did not say 5-HTP will cause gyno,nor did I say serotonin, SSRI’s, or tryptophan would. If so there would be alot of Americans with some serious problems right now. It probably won’t. But it is still a small possibility through the prolactin mechanism. You are turning my words around to make an argument.
Scrub…here is a study I got off of Pubmed. I could swear I’ve read something about serotonin blunting dopamine but I could be way off on that one. I’ll have to research.
: Psychopharmacology (Berl). 1982;78(1):38-43. Related Articles, Links
The effect of IV L-tryptophan on prolactin, growth hormone, and mood in healthy subjects.
Charney DS, Heninger GR, Reinhard JF Jr, Sternberg DE, Hafstead KM.
In order to assess the effects of increased CNS serotonergic function in humans on prolactin (PRL), growth hormone (GH), and mood, IV L-tryptophan (TRP) was administered to ten healthy subjects. The TRP infusion induced robust increases in PRL in all ten subjects. A significant increase in GH concentration was also observed, although the response was more variable. The subjects reported feeling significantly more ‘high’, ‘mellow’, and ‘drowsy’ following the TRP infusion in comparison to placebo. These findings indicate an important role for serotonin in PRL and GH secretion, as well as in mood regulation. The IV TRP challenge may be of use in the study of serotonergic function in a variety of neurologic and psychiatric diseases.
Publication Types:
Clinical Trial
Controlled Clinical Trial
Randomized Controlled Trial
PMID: 6815695 [PubMed - indexed for MEDLINE]
TrenchDawg: I would say start with 50mg 1-2 hours before. If that doesn’t do the trick, try again with a higher dose. I would say…no more than 200mg.
Except from:
Management of and Counseling for Psychotropic Drug-Induced Sexual Dysfunction
from Pharmacotherapy
Mary A. Gutierrez, Pharm.D.,Glen L. Stimmel, Pharm.D.
Neurotransmitters and Sexual Function
Although the effect of psychotropic drugs on various hormones is not certain, their effect on several neurotransmitters influencing sexual function is well established. Dopamine is the neurotransmitter in the mesolimbic "pleasure center." Increasing dopaminergic activity may enhance sexual response, and blocking it may compromise response. Among psychotropic drugs, many antipsychotic agents are dopamine blockers, whereas the antidepressant bupropion has mild dopamine-agonist activity. A reciprocal relationship exists between serotonin and dopamine, in that serotonin can diminish the release of dopamine in the mesolimbic area, thus decreasing sexual response. Drugs that increase serotonergic activity are most commonly associated with delayed ejaculation in men and anorgasmia in men and women. In addition, the serotonin 5-HT2 receptor may block descending pathways from the brain stem to spinal neurons and interfere with spinal reflex centers necessary for ejaculation and orgasm. This mechanism underlies the delayed ejaculation and anorgasmia seen so commonly with serotonin agonists and explains why some antidepressants with 5-HT2-blocking effects (nefazodone, mirtazapine) do not cause anorgasmia.[4]And there you have it. Thanks man, makes sense.
Smoke a spliff.
I wasn’t attempting to start an arguement, r100. I just found your claim highly unlikely.
According to this research, though it seems that an increase in prolactin could be seem with tryptophan injections. HOWEVER, the dosage is not stated. I would suspect it would need to be in such doses that would make it impracticle for anyone to get that amount realistically from 5-HTP pills or food.
But I retract my original objection, it seems you are correct that prolactin levels can rise with serotonin increase.
I have found no use for 5-HTP in anything other than helping me sleep. Especially, if I have been taking too many stimulants or I’m stressed out and can’t sleep, then it’s very useful, up to 200mg. If I took it before my girlfriend came over, I can guarantee I’d fall asleep before coming…