Greetings. I am on trt. I take 10mg a day T Cyp via injection. My shbg is 10. It was 9 before trt. I am 44. I have been on trt one year exactly. I have been lifting consistently for 32 years.
My questions are 1) would a bit of dbol raise my shbg ? 2) would adding dhea and or pregnenolone help raise my shbg?
TRT decreases SHBG is almost everyone, except for type 2 diabetics which will see an increase in SHBG on TRT.
SHBG is one of the most difficult sex hormones to affect.
My SHBG went up on TRT. I too am on daily injections, not sure if that has anything to do with it as it didnt increase (or decrease for that matter) on once weekly.
Mine as well, 11-> 24 nmol/L. More than double. If I wasn’t on TRT and didn’t have metabolic syndrome, my SHBG would be even higher, because Jatenzo lowers SHBG by up to 40 percent.
I’m on oral Jatenzo @ 237 mg twice daily.
Interesting. The only thing that seems to negatively affect mine, as to be expected, is if I bring in any DHT derivatives. An experiment with Primo hammered my SHBG into single digits.
Mine dropped from 25 → 18 in first 6 weeks…guessing it will be lower again when I retest in 4 weeks.
mine is around 11 or so and I gave up on any efforts to raise it. it appears to be virtually impossible. if anybody knows how let me know.
Do you have low SHBG symptoms?
no that I know, what are those? i noticed that I feel the best on daily Tprop injections, maybe this is due low shbg
Yes, definitely .
I have read that adding in a good amount of dietary fiber helps. So that’s what I’m doing. Next bloods will tell if it works
Edit: not sure if I replied to the right person on this.
Symptoms are usually the same as high T since the levels of each are generally inversely correlated for a natural person (no anabolic steroids).
I’m not even close to an expert on hormones but SHBG level seems to be less useful once exogenous T is introduced. SHBG regulates T:E ratio and exogenous T puts that somewhat out of whack and you then manipulate the ratio by changing the T dosage, which takes the place of the role of SHBG. Again - this is my dime store education perspective on it.
My SHGB tanked recently due to oxandrolone and I felt perfectly fine and blood test other than SHBG was also fine. So I didn’t really care about what the SHGB blood test number said. Im sure somebody smarter than me can tell me why I’m an idiot and will be dead in a year from low SHGB.
Do you have an opinion on dhea, dbol, pregnenolone effects on shbg?
I should have put in my original post that I just recently moved to every day 10mg T cyp dosing in order to combat the low shbg. I also added fiber into my diet, cut more sugars, etc
There’s growing evidence suggests that SHBG is internalized and plays a role in regulating intracellular hormone action three different ways.
SHBG also enhances testosterone induced reduction of androgen receptor mRNA expression.
Evidence indicates that a low level of SHBG may be associated with increased risk of cardiovascular disease.
You don’t want SHBG low.
Looks like clomid raises it up. I may add some into my regimen
Clomid blocks estrogen in the liver, pancreas, heart and brain, a real freak show. Estrogen is needed for libido, libido is in the brain, sexual thoughts and the most common side effects of Clomid, are low or zero libido.
Drugs usually solve one problem and create many more.
If Clomid really did solve the problem for men on TRT with low SHBG, it would be common knowledge, everyone would be raving about it, but you don’t, it doesn’t work, because there’s too many downsides.
Take the blue pill.
yeah, clomid appers to be absolute garbage, not sure why anyone would take it
I also want to add a guy over at Excelmale tried Clomid with his TRT and increased the Clomid dosage and started having problems within days, now he no longer responds optimally to TRT on any protocol.
He now struggles to feel good on TRT.
If you found a protocol that works, you feel optimal, don’t f*** with it!
Yeah clomid can F you up.