[quote]hungry4more wrote:
Obviously you’re very knowledgeable on this subject, and this is something I’ve wondered…how many types of the flu are generally contained in the vaccine? IIRC, aren’t there hundreds/thousands of different strain floating around at any given time?
You’ve got a lot of good points. And you’re right, there’s any bigger issues with where the government spends its money. With how strongly the gov’t pushes vaccines like this (I can understand things like smallpox and what not, ones that are relatively often serious or fatal), it just frustrates me, like anything else that seems like wasteful spending.
To be fair, isn’t it safe to assume that the vaccines for a constantly and quickly evolving virus like influenza well typically be a step or two behind?[/quote]
The traditional flu vaccines contain three different strains of the flu (trivalent vaccines), while FluMist is, I believe, the only one to contain four (quadrivalent). And, yeah, the number of influenza strains is at the very least in the hundreds, though I’m sure a more accurate statistic is floating around somewhere and I wouldn’t be surprised if it is in the thousands or greater (viruses are the most abundant biological entity on the planet). The issue with that is isolating and differentiating the strains, which many times is more academically useful than clinical because the drugs and immune responses can work equally well across various strains.
I absolutely agree that the “guess work” that goes into creating the yearly vaccine leaves something to be desired, though… but, unfortunately, right now it is the best we can do. The statistics for how well the vaccines do their job varies depending on the source; I believe the CDC ballparks it at 90%, give or take, while a recent study in (I think) the Lancet puts it at closer to 60% for adults given traditional vaccines (80% for children given FluMist).
Which leads me to something I forgot to mention the other day: FluMist is generally seen to be more effective in children than in adults. Where I work, it is considered to be the “children’s vaccine”.
So, yeah, there needs to be some degree of improvement if the newer study reflects the reality a little better than the CDC. What is interesting is that just recently, a new antibody was discovered that is HOPED to be the stepping stone to a “universal” flu vaccine that would be effective against all forms and, as such, would only be needed as a one-time shot.