Layman' Training Log/Diary - Bodybuilding - (Red Pill/Blue Pill)

[johann77]

Bolger and Jorgensen studied about 100 chemically synthesized thyroid hormones with regard to their binding kinetics to the nuclear thyroid receptor.

Yes it binds, but about 100 times weaker as T3 does. And there is a lack of evidence that it localizes to the nucleus.

I tried to explain this previously:

UK TRT Help with/ Blood Results

Of course endocrinologists do care about data and evidence. It’s a different question if they are willing to constantly update their knowledge as science progresses. @kratom_dumper Let me very briefly explain why rT3 is meaningless for the diagnosis of thyroid disease: The common understanding seems to be here that rT3 binds to thyroid receptors and block them. In order for it to do so rT3 needs to be transported into the cytoplasm from the extracellular space it needs to be shifted into t…