Below is my latest lab corp blood work. Cliff notes Testosterone on injection day is 1100, Estradiol is at 9… Free test is 35 and SHBG is at 49.
two concerns is my high TSH constantly between 4.5 and now 4.8… My estrogen is very very low and this time around my Alkaline Phosphate is low ? Seeing what your thoughts are on my latest blood work ?
CBC With Differential/Platelet
WBC 5.3 x10E3/uL 3.4-10.8 01
RBC 5.43 x10E6/uL 4.14-5.80 01
Hemoglobin 16.0 g/dL 13.0-17.7 01
Hematocrit 47.7 % 37.5-51.0 01
MCV 88 fL 79-97 01
MCH 29.5 pg 26.6-33.0 01
MCHC 33.5 g/dL 31.5-35.7 01
RDW 13.0 % 11.6-15.4 01
Platelets 268 x10E3/uL 150-450 01
Neutrophils 49 % Not Estab. 01
Lymphs 39 % Not Estab. 01
Monocytes 8 % Not Estab. 01
Eos 3 % Not Estab. 01
Basos 1 % Not Estab. 01
Neutrophils (Absolute) 2.5 x10E3/uL 1.4-7.0 01
Lymphs (Absolute) 2.1 x10E3/uL 0.7-3.1 01
Monocytes(Absolute) 0.4 x10E3/uL 0.1-0.9 01
Eos (Absolute) 0.2 x10E3/uL 0.0-0.4 01
Baso (Absolute) 0.1 x10E3/uL 0.0-0.2 01
Immature Granulocytes 0 % Not Estab. 01
Immature Grans (Abs) 0.0 x10E3/uL 0.0-0.1 01
Comp. Metabolic Panel (14)
Glucose 86 mg/dL 65-99 01
BUN 19 mg/dL 6-24 01
Creatinine 1.15 mg/dL 0.76-1.27 01
eGFR If NonAfricn Am 79 mL/min/1.73 >59
eGFR If Africn Am 92 mL/min/1.73 >59
BUN/Creatinine Ratio 17 9-20
Sodium 138 mmol/L 134-144 01
Potassium 5.1 mmol/L 3.5-5.2 01
Chloride 99 mmol/L 96-106 01
Carbon Dioxide, Total 26 mmol/L 20-29 01
Calcium 9.9 mg/dL 8.7-10.2 01
Protein, Total 6.6 g/dL 6.0-8.5 01
Albumin 4.8 g/dL 4.0-5.0 01
Globulin, Total 1.8 g/dL 1.5-4.5
A/G Ratio 2.7 High 1.2-2.2
Bilirubin, Total 1.2 mg/dL 0.0-1.2 01
Alkaline Phosphatase 32 Low IU/L 39-117 01
AST (SGOT) 42 High IU/L 0-40 01
ALT (SGPT) 27 IU/L 0-44 01
Lipid Panel w/ Chol/HDL Ratio
Cholesterol, Total 178 mg/dL 100-199 01
Triglycerides 58 mg/dL 0-149 01
HDL Cholesterol 68 mg/dL >39 01
VLDL Cholesterol Cal 11 mg/dL 5-40
LDL Chol Calc (NIH) 99 mg/dL 0-99
T. Chol/HDL Ratio 2.6 ratio 0.0-5.0
Testosterone,Free and Total
Testosterone, Serum 1103 High ng/dL 264-916 01
Free Testosterone(Direct) 34.9 High pg/mL 6.8-21.5 01
Thyroxine (T4) Free, Direct, S
T4,Free(Direct) 1.36 ng/dL 0.82-1.77 01
DHEA-Sulfate 434.0 High ug/dL 102.6-416.3 01
TSH 4.850 High uIU/mL 0.450-4.500 01
Prostate-Specific Ag, Serum
Prostate Specific Ag, Serum 0.5 ng/mL 0.0-4.0 01
IGF-1
Insulin-Like Growth Factor I 195 ng/mL 90-278 02
Estradiol, Sensitive 9.9 pg/mL 8.0-35.0 02
This test was developed and its performance characteristics
determined by LabCorp. It has not been cleared by the Food and
Drug Administration.
Methodology: Liquid chromatography tandem mass spectrometry(LC/MS/MS)
Triiodothyronine (T3), Free 3.5 pg/mL 2.0-4.4 01
Sex Horm Binding Glob, Serum 49.2 nmol/L 16.5-55.9 01
I assume you’re not taking an ai, based on that you might be a candidate for a bit of estrogen replacement added in. If you are taking an ai, stop.
Well, I say that, but I should ask first, how do feel? Maybe just leave things alone, though low estrogen is associated with osteoporosis, that might be worth suplementing for. Also, even if you feel pretty good, it might be worth trying, you can always stop it.
I don’t know about the alkaline phsosphase.
Edit:
After consulting Dr. Google, alkaline phosphase can be assiciated with nutritional deficiency. Are you dieting currently? It might be worth a review.
I feel great… they have me on two shots a week of Test Cyp… 160 mg split into two doses. Over the last few weeks I have been feeling lethargic but chalked that up to my diet and doing a ton of working out.
If you’re feeling great, i probably wouldn’t mess with anything. If your still tired, try bumping up calories a few days and see if that helps. If it does you might just be in a deep deficit and haver to put up with it until you hit your goals.
Could be a lot of things from calories to other deficiency, to sleep issues or stress, or your body just decided to f’ with you a bit, your protobrain has quite the sense of humor, even if it is a bit out of step with what your conscious self thinks is funny.
It’s hard to diagnose over an internet forum and my specialty is enterprise scale computing not medicine.
This is more than likely a nutritional deficiency, maybe zinc. I think it’s highly likely you’re working out so hard you nutrition is falling behind and you are running out of stuff.
When I started working out 5 days a week, I wasn’t eating enough protein and would feel horrible right before my meals.
All other thyroid labs look fine, are you taking any iodine supplements? If not taking any iodine supplements, a high TSH while all other thyroid labs are normal, this is subclinical hypothyroidism.
^^^^ A low estrogen result will cause these symptoms. You likely have an aromatase deficiency (if not taking an AI) and need HCG to increase it to at least 30 or higher.
Staying at this estrogen level over the long term is not good and why do you feel fine now, in time you’ll start to have more severe symptoms → osteoporosis.
With your hematocrit being almost mid-range you probably can handle a high T dose, but am unsure estrogen would increase high enough.
I may be pushing it too hard. Spring is here and I am doing my strength training 5 days a week, cardio and started overspeed training again for golf/baseball. Since I am 40 I need more speed. I have never taken an AI while on TRT. I thought about upping my testosterone dosage since it seems like I am not really converting any of the shot into estrogen and my blood is good on 160mg a week. My TSH was at 2.8 when I started 2 years ago and has hovered around 4.5-5 the entire time. I do not take iodine ?
Would my lack of energy and sleepiness come from having such a low estradiol level ? I am eating better than ever but always seem to be dead tired around 7pm?
Update 06/15… I have brought my estradiol up to 45 ! I thought I was feeling good but my god the last few weeks have been awesome. My strength has gone up… body fat is melting off… mood is so much better and endurance is back. My tendons are also feeling 1000 percent better !
I eliminated grape seed extract from my morning supplements and reduce xt… I thought it was a cortisol blocker but apparently had some anti estrogen properties as well. I am also not afraid to drink a few hoppy beers when I feel like it… I always viewed estrogen as the devil for men… but man… I am leaner, happier, my sex drive is through the roof, strength and recovery is better, sleep it better, bowel movements better… I want to keep that E2 right where it is.
