[quote]GeorgeCulp wrote:
Its kinda timely that this GFR issue has come up as I too am trying to get my GFR above 60. It is now 52.
At first we felt I was chronically dehydrated. I drank a lot of coffee and not much outside water. I dropped the coffee to 1 cup in the am and starting consuming 1 gallon of water a day of which 1 quart was cranberry juice. Did this for one week. Retested my GFR and there was no change. Still 52.
My BUN/CR ratio did go from 20 to 16.4.
Serum creatinine remained the same - 1.4
Also, I did not train at all for 5 days prior to these tests. My ALT went from 165 to 107. AST went from 147 to 92. Still elevated but better and the conclusion was due to no training (and no im injection during the 5 day period)
My MD wants me to drop ALL supplemental protein and any other isolated amino acids and replace with whole food and retest in one week to see the effect on my GFR. I take in about 100 grams of supplemental protein and about another 110 from whole food. I have no idea whatsoever if this will matter to my GFR[/quote]
This is why I am keeping this information around. If your eGFR was 52 for years it would be no big deal. Hard to smell a trend there with a single datapoint. Your liver numbers are spooking me. I was making 5-6,000 per week last summer when I decided to quit my job and take the summer off. I fell into the bottle hard for a month in the middle of the summer and my numbers were nowhere near that. 60 is worst ever, 30 or below otherwise. Why are they so high ?
A thought that may or may not be relevant here: Kidney function can be thrown off by adrenal issues. Specifically, low aldosterone will lead to high creatinine and renin and low GFR. (I have Addison’s – full adrenal failure – and this is a key telltale we watch for when adjusting medication dosages.)
rbarker, my GFR is 52. And we did not discuss what to do if the present test does not work.
HiredGun - you bring up a good point in the possiblilty that normal for me maybe slightly below 60. As far as the liver enzyme numbers - they have always been elevated and we feel they are an artifact of heavy lifting. As I posted above the differences when I took only 5 days off from training.
As well, I have suffered a DVT - deep vein thrombosis aka “leg clot” several years ago and still remain on warfarin therapy. The result is that when I bruise I bruise worse than “normal” for me. IM injection destruction, training, and bruising the doc and I feel raises the AST and ALT. However, the training is the major contributor.
[quote]Drexel wrote:
A thought that may or may not be relevant here: Kidney function can be thrown off by adrenal issues. Specifically, low aldosterone will lead to high creatinine and renin and low GFR. (I have Addison’s – full adrenal failure – and this is a key telltale we watch for when adjusting medication dosages.)[/quote]
That is terribly interesting to me because I have had to take high dose prednisone several times.
So you take prednisone continously since your adrenals make no cortisol3 ?
[quote]GeorgeCulp wrote:
rbarker, my GFR is 52. And we did not discuss what to do if the present test does not work.
HiredGun - you bring up a good point in the possiblilty that normal for me maybe slightly below 60. As far as the liver enzyme numbers - they have always been elevated and we feel they are an artifact of heavy lifting. As I posted above the differences when I took only 5 days off from training.
As well, I have suffered a DVT - deep vein thrombosis aka “leg clot” several years ago and still remain on warfarin therapy. The result is that when I bruise I bruise worse than “normal” for me. IM injection destruction, training, and bruising the doc and I feel raises the AST and ALT. However, the training is the major contributor.[/quote]
Welcome to the club. Last summer they had to pump 15 lbs of water into my I.V. and after CT scan, spinal tap and MRI/MRV they told me I suffered a Sagittal Sinus Thrombosis or Stroke. I was moved into the ICU and it was $64,000.00 buckaroos.
I took 3 months of warfarin and used a bit of T cream but then lined up an $8000.00 2-hour MRI/MRV Jan 2 2011 and talked the girl into showing me the results days later - Totally resolved and normal for age and weight. I got off the warfarin. Last week I skied BreckenFRIDGE with 10 guys from my hometown and led the charge all day into the moguls, anemia - gone, cardio issues - gone. At 12,000 feet I went long in the bumps before needing to stop.
GP/GI/Neurologist repeatedly emphasized hydration and looking over my blood results I can see my platelett count goes off the chart near 700 one month prior to every UC flare setting the stage for stroke at the end of every hot summer. This time I am educated and ready for it. There will be no UC flare and other complications this hot summer.
The test for hydration since I consume sulfasalazine and never pee clear is to weigh myself, I can lose 3-5 lbs overnight.
Hired Gun, If you don’t mind me asking, what is your age and what type of cardio problems did you have. I’m asking because I too have some cardio issues that I’m dealing with. You can PM me if you don’t want to discuss on the forum.
That is terribly interesting to me because I have had to take high dose prednisone several times.
So you take prednisone continously since your adrenals make no cortisol3 ?[/quote]
Yes. Specifically, I take dexamethasone 0.5 mg (equivalent to about 5 mg prednisone or 20-25 mg hydrocortisone] to replace the cortisol, florinef 0.1 mg to replace the aldosterone, and DHEA 50 mg every day. (Also 100 mg T-cyp once a week, but strictly speaking it’s unclear if that’s related.) It’s a lifelong thing, which kind of sucks, but as incurable autoimmune diseases go I could have done a lot worse.
[quote]GeorgeCulp wrote:
rbarker, my GFR is 52. And we did not discuss what to do if the present test does not work.
HiredGun - you bring up a good point in the possiblilty that normal for me maybe slightly below 60. As far as the liver enzyme numbers - they have always been elevated and we feel they are an artifact of heavy lifting. As I posted above the differences when I took only 5 days off from training.
As well, I have suffered a DVT - deep vein thrombosis aka “leg clot” several years ago and still remain on warfarin therapy. The result is that when I bruise I bruise worse than “normal” for me. IM injection destruction, training, and bruising the doc and I feel raises the AST and ALT. However, the training is the major contributor.[/quote]
HY GEORGE , nice to meet you
Did you find out why you had the DVT…I MEAN WHAT IS THE REASON?
HY GEORGE , nice to meet you
Did you find out why you had the DVT…I MEAN WHAT IS THE REASON?
[quote]GeorgeCulp wrote:
rbarker, my GFR is 52. And we did not discuss what to do if the present test does not work.
HiredGun - you bring up a good point in the possiblilty that normal for me maybe slightly below 60. As far as the liver enzyme numbers - they have always been elevated and we feel they are an artifact of heavy lifting. As I posted above the differences when I took only 5 days off from training.
As well, I have suffered a DVT - deep vein thrombosis aka “leg clot” several years ago and still remain on warfarin therapy. The result is that when I bruise I bruise worse than “normal” for me. IM injection destruction, training, and bruising the doc and I feel raises the AST and ALT. However, the training is the major contributor.[/quote]