Looking through your posts I saw this:
Total T: increased from 1989 to 2338 (Ref 250-1100)
Free T: increased from 192.9 to 215.1 (Ref 35-155)
SHBG: increased from 110 to 114 (Ref 15.5-55.9)
Estradiol: decreased from 51 to 50 (Ref <29)
You said these were at 4 weeks. That total T is nuts lol. You said the conversion for the free T seen here would bring you to the ideal point of 21.5?
Yeah man, total T is crazy! But that’s the reality of having an SHBG that high. I’ll need to push the total T even higher to feel fine.
21.5 may be an ideal point for a number of guys, but definitely not for me. That’s an FT:T ratio of .09%. Optimal range, as I understand it, is usually considered 2-3%.
And you were just using 1 click twice per day at that point?
I’m the opposite, low SHBG, sucksss
I would suspect within 2 more weeks most of it will be gone since you were on a small dose.
For me it took about 4 weeks for the estrogen to dial down when I switched to cream. Keep in mind I was at 210 cypionate and went straight to 3 clicks am and Pm haha.
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I feel dumb that I forgot this crucial piece of info until I looked through my wife’s notes from my doctors appt. He was also concerned about scrotal application because I never had a test for DHT.
As you know from their debate over on EM, Saya and Nichols differ in opinion on the long-term effects of elevated DHT.
Look at the video lifting dermatologist from that group put up . It says DHT vs good or bad.
DHT is over the counter in countries . Over 80 years they have never had issues with any of this DHT stuff. All the DHT in prostate or this and that has zero case studies backing it up. There are zero case studies showing DHT to be harmful.
I’ll post the video for you via email. You are in such a small amount as well that it won’t created 100s so don’t worry to much about it. I’m on 300 daily and I’m ok.
Not trying to throw this guy under the bus but saya is the same doctor who gives men with super low e2 an ai and says take this with every shot without caring if the e2 crashes. We tell the patient to think again. Patient calls defy and they say “oops”…
He told you inter testicular estrogen. Where are these things coming from?
Now they are scared of high DHT yet high DHT does not cause any issues in the prostate. There are several studies on the Facebook group. Look through it and towards last month sometime. You can see all the presumptions of DHT have not been proven true.
I read a recent post on em you will find that he pretty much agrees that ai are not needed in majority of men and that the ai is jsut for covering his own ass. This makes him seem as the type that picks up industry wide changes last . He is not at the fore front of change or adapting new methods. He does not have the clinical experience to say anything about scrotal cream because he doesn’t attempt to innovate.
Ask saya about dr. Rouzier. He will say that is the wizard.
Then realize Dr. Nichols follows Dr. Rouzier method and they both stand by this method. Both have been doing this for more than a decade and not one person has said “I had to switch because DHT caused me to … fill in the blanks.
Now I wouldn’t use the cream if I was balding. No way 
In the other hand the reason DHT is so awesome is becusse this is the hormone for verility, libido and etc. without DHT many benefits of trt cannot be realized.
Therefore a single click is producing DHT as though you are injecting. 150mg cypionate.
End of day research Dr. Rouzier . Any hormone doc will tell you that Rouzier has probably forgotten more about hormones than anyone has memorized. That’s how high they hold the mans knowledge. If he trusts in this method I can trust to.
Hope that helps bro.
Sorry if I ramble on.
There is no correlation between serum T or DHT and prostate tissue
concentrations of DHT.
He is the guy they call whenever an expert is needed to testify in a malpractice case.
Yup I just hope it helps folks wrap their head around the talk around HRT. Even professionals dip their toes in bro science. Sad
Good stuff man. I had another question. I’ve run into problems with the click dispenser. Twice now I’ve clicked it a quarter turn and nothing came out. I proceed to click it again after waiting a few seconds and almost twice the regular amount comes out. This makes it difficult to manage dosage. Any experience with this?
Ya get a pin or needle. The cream dried up in the canal. Jsut stick a needle in and it should come out.
Keep the cap on there to keep it moist helps.
So I’ve been on the cream on the scrotum for a week now, 1 click twice a day. I’d say from last Friday until this Wednesday I felt like a god. Raging libido, strong as hell I the gym with a bottomless gas tank, muscles were filled out, slept like a baby, really positive and upbeat mood, finally remembered what it was like to live again. Then I gradually started to feel like shit again, so utterly depressing…
I think I got a boost from the test cyp still being in my system in addition to the cream. I’m sure I’ll be feeling even shittier come next week when it halves again. I’ll have to contact Defy and request bloodwork to see where I’m at before I consider a dose increase of the cream.
*Contacted Defy who stated I didn’t need testing for 7 more weeks. This doesn’t sound right to me, does a cream take that long to build up to a stable state?
I read this was very happy for you… until I read the rest of it. But at least you know it is possible!
That’s where I’m trying to keep my mind. If it happened once it can happen again, just a matter of dialing things in. I do miss that feeling though!
How’ve you been?
You’ll figure it out! Just keep at it!
Well, I didn’t die deadlifting this morning so things are looking up!
Lol that’s what I like to hear. Worse places to die than the gym though!
No you don’t need a test to tell you how you feel. Once the Cyp leaves the body just see how you feel. You can always add another click and see how you fair. I honestly don’t think you need to worry about it. If it is to much just stay with one click or ask for 25mg clicks so you can take 75 instead of 50mg increments . Make sense?
And didn’t forget it won’t be staying in your body for weeks like cyp
I think the 75mg idea is a good one. I thought about adding another click but I don’t like the idea of running out early (unless you meant just one click one time to see?). I’ll contact them sometime next week if I’m still feeling like shit.
I know the cypionate is going to take about 3 weeks to leave my system, I’ve come off of it before.
So 1 click on the cyp is probably two clicks but you could split that up over this day instead of all at once. I bet you’ll feel better this way.
Just saw a live video with dr nichols and he said most common cream protocol is 2 am and Pm. He has plenty of folks 1 am and pm as well.
So instead of 2clicks or 1.5 once daily You should be fine trying 1 click am and Pm when cyp is gone.
Because the am dose peaks 5 hours out and declines at 12 hours in. Adding a Pm dose will get you to stay around 50 to 75mg dose per day and as long as you keep dosing every 12 hours you should keep 50-75 in the system. I’m guessing at what the numbers are but you get the logic. Achieve stable levels like we do with daily injections.
Other option of 75 only in am might spike you to 100 and then decline back to 25 by 24th hour. You might feel horrible by the time you fall asleep and wake up.
This is why he does am and Pm.
Regardless you have many options and you won’t have to wait weeks to resolve any symptoms because it’s mostly out of your system by 36 48 hours. For some 72 hours but even the amount left in the system is negligible.
Hope I’m clear and not confusing.mmn