Is this "No AI" Thing Really for Everyone?

I hear ya. I was one of those people who “needed” an AI, until I realized that not only didn’t I need an AI, but it was actually harming me by taking it. 1/4 pill twice a week. I thought what harm could that possibly do?

Can you provide anything that shows taking it at those low doses causes harm?

There’s no quantative data indicative taking TRT in a manner that “optimises” the patient is without any long term harm either. Most on here, myself included opt for maintaining a median TT around 700-1200 (1200 being on the high side) with minimal fluctuation. This doesn’t mimic natural physiology (circadian rhythm), exogenous T also drops SHBG. Someone with a natty TT of 1,000ng/dl typically won’t have the same elevated FT comparative to someone on TRT.

Do I think the harms are drastic? probably not for the health conscious adult male. For the sedentary, hypertensive, obese male going on TRT… absolutely, a median TT of 1,000ng/dl with an associated elevated FT might be enough to elicit enough downstream effects (pathophysiological alterations regarding RAAS, hyperviscosity of the blood, subclinical autonomic dysfunction via beta adrenergic receptor up-regulation etc) to trigger a stroke/myocardial infarction.

Some guys, particularly those with JAK2 mutations and the likes might acquire polycythemia on 5g Androgel/day, whereas I can indefinitely use 200mg/wk (but don’t) without my red cell count budging.

My point being, those who talk of aromatase inhibitors with such disdain, as if taking them is the equivalent of drinking bleach are at times somewhat disingenuous as their views are far from consistent. Plenty add drostanolone, 19-nortestosteroone, metenolone, oxandrolone and stanozolol to their TRT regiments for “wellness” as prescribed by TRT clinics and/or acquired from the black market with drostanolone… Wellness is a fancy term of “I use steroids, but in lower dosages and don’t wish to be colloquially associated with the blast and cruise crowd.” Plenty of “trt” guys use 250mg/wk or so indefinately

Somehow all of this isn’t poison, but a tiny bit of anastrozole is… lol… haaaaaaaaaaa

7 Likes

I’ve heard those who carry the gene for HH but don’t actually have it can respond very strongly re erythrocytosis with TRT, are at higher risk for thrombosis.

You’re on TRT for life correct? I knew a parent who had HH, constant phlebotomies…

Are we going to talk about the adjunct chemicals people use as TRT? Do we REALLY think dropping HDL by 30%, increasing LDL 10-15% with 100mg mast/wk is better to use as an AI relative to say… .25mg anastrazole/wk

Not to mention the increased risk of polycythema, autonomic dysfunction etc that occurs with higher androgen load. Masteron would be an AWESOME TRT drug if it didn’t skew lipid panels so badly (for most)

Formula branded as @unreal24278’s wonderHRT. 75mg testosterone enanthate/ml 75mg drostanolone enanthate/ml, grapeseed oil, 75mg alirocumab, a smidge of benzyl benzoate and whatnot. Unreal makes billions! Men sign up by the million, many satisfied marriages

1 Like

If only we could selectively change “air” to contain more nitrogen and oxygen. NiTrOuS oXiDe. Everyone would be laughing a whole lot more, everyone would have extensive neurological damage mediated by vitamin b12 deficiency… everyone would probably be dead #hypoxia

Well… the concept was fun…

Pretty much all drugs / hormones are poison in the wrong dose. It seems inconsistent to be okay with one taking testosterone, which has caused plenty of premature deaths, but not an AI.

Yep. I think much of this is around public perception of steroids. Many in the general public think if you are on steroids, that you look like a bodybuilder. Most don’t look impressive at all, and more guys take them than many people know. These guys don’t want people to think less of them because there must be something wrong with them if they are on steroids, and look the way they do. Additionally, they don’t want to be lumped in with the gym bro steroid users, as you said.

Get the fuck outta here with this shit. Work on your self esteem instead of trying to “show” you’re intelligent. No one cares.

Christ, i leave this place for a few months and the same ole idiots are still blabbering on…

You have evidence that testosterone has caused plenty of premature deaths when taken in a trt regimen? I didn’t think so.

Unless I’ve advocated that those aren’t poison, it’s irrelevant. Either anastrozole is poison for men on trt, or it isn’t. All those other things aside.

DBossa has provided evidence ad nauseam. He’s posted multiple videos from his YouTube channel.

It’s only 2-5% max, MAYBE 8-10% LIFETIME prevalence within countries where use is most common

Eh can you provide evidence to anastrazole being “poison”

And all credibility lost right there in one post :frowning:

1 Like

:woman_facepalming: That was the point lol. Calling it poison is silly, as it has benefits for some if used properly. It can also have a lot of negatives if used improperly. It comes down to the correct dosage, and the person actually needing it.

This is a false dichotomy fallacy, unless you consider nearly all medicine to be poison. When is the last time you heard of a drug with no side effects?

2 Likes

Actually its not.

His point being quantity has a huge bearing on whether any chemical substance is poisoning your body.

Small glass of wine = health benefits (proven)
Large quantities of alcohol = poison.

Small dose wafrin = thins the blood for medicinal purposes.
Large dose wafrin = rat poison
Paracetamol @ 1gram = pain killer
Paracetamol @ 10g = probably kill you

You can literally do it with anything - however you’ve latched on to some studies that look at much larger doses and some negative effects and arent open to the possibility that dosage has a bearing on this.

I’m open to both- if someone shows me it is damaging at very low doses I’ll have to seriously consider if its worth the risks.

However at the minute - a very low dose A.I has improved the quality of my life no end over the test only dose that wasn’t working for ME.

Thats not me telling other people to take it- thats me stating that for my physiology I was just not able to have decent T levels that were therapeutic without getting issues associated with raised e2.

Once I dropped my e2 those issues have gone away.

I still.come back to… raised e2 causes prostate growth- thats a FACT. So in 20 years people deciding to run really high e2 levels are going to be struggling to have a piss without an alpha blocker… are they poison?

4 Likes

There is a lot in the UK (or at least I’ve heard that). Before looking into it, I figured it was sub 1%.

I just would like to see his proof for it being “poison” since he jumped on another member for grammar. I work in the pharmacy field, I am not aware of anastrazole being “poison”, there are other compounds listed as such.

2 Likes

Lol your posts are well written, I know this.

@mnben87

Sorry despite re-reading the thread multiple times I cant see what you are replying to…

What are you saying is maybe 8-10% in the UK?

What percent of men are or have used steroids. I’ve heard in the UK the numbers are pretty high. Growing up, I thought steroid users were few and far between. Now I suspect that a lot of guys are using. Many don’t look the part.

I doubt it is 10% in UK, just that I’ve seen several things recently about steroid use really growing in the UK. I did see one study where a bit over 1% of men (something like 19-59 year olds) said they used in the past year. How many did not admit it?

Just the amount of guys on TRT has blow up. That has to have made the percentages of steroid users go up significantly. Not saying that all steroid use is bad, it can increase health perhaps if done correctly. But TRT involves injecting a steroid, so if you are on TRT you are a steroid user.