Is Lack of Estrogen Causing Issues with My Sleep?

Here’s is my protocol 50 Mg of Test Cyp, IM E3D. I recently raised that from 40 MG about 2 months ago in an effort to raise my estrogen.

Lot of others stuff has happened. I went through a stint of Xanax for about 2 months. I’m off that now for 2.5 weeks.

My sleep is awful. I fall asleeep very easy sometimes crashing. But I wake up early at like 3am and really just in general my sleep is crap. I know I also have a mild case of sleep apnea which I’m in the process of getting a mouth piece to help with that.

All this said, from what I’ve read on here, low estrogen can impact sleep and from what I can tell I still have issues with really low levels. I’m testing them again tomorrow but here is my recent labs. How can you get estrogen back up or to a level that will help my sleep? I’m about to go off TRT but I don’t want to. I can’t continue to sleep like this though.






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Do you know why your estradiol is so low?

No idea! Is it because I’m doing IM?

Doubt it.

I assume you’re not taking an AI?

I would get your E2 checked again. Make sure it’s Estrodiol (sensitive)

Then I would up my testosterone and try to get it to the top of the range and see how that feels after a couple months.

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When my e2 was low (19pg or below) all I wanted was sleep. Couldn’t get out of bed, sleep 10-12 hours and still feel tired.

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Glad you’re off Xanax. I bet if you raised your T, your E will go up. 660TT is kinda weak for being on TRT. T levels at 1000TT should be more therapeutic also.

It seems more helpful if we referenced TT levels at the trough. Or at least a point where levels make some relative sense.

I only get my TT tested at my trough (the last morning before the next injection in the PM)

You can try taking 25 mg dhea

Absolutely. His dose indicates that he could use a bump up though, and I tend to go by that, along with numbers. I inject daily so my trough tends to hover around 1000, and I sleep like baby. Still might not be an E issue though.

I agree his T levels are low for being on TRT and his E could be increased slightly, but it sounds like many posting have lost sight that his main inquiry, issue and complaint is sleep.

I’m not convinced that would be improved by increasing his T and E levels. If anything, increasing both tends to be stimulatory and could make his sleep worse.

OP, you’re likely still dealing with the after effects of what Xanax has done to your GABAergic system.

Do you take anything before bed to help sleep?

Some recommendations that help me sleep: magnesium glycinate, zinc, l-tryptophan, omega 3’s and a probiotic that contains both Lactobacillus helveticus (L. helveticus) and Bifidobacterium longum(B. longum).

I am not taking an AI. I’m going to get my E2 checked again this week. I’m not sure I want to up the test. I fear it would make things worse. But I’ll keep it on the list of options. I thought a big out lowering it too.

I r been taking melatonin for now. You might be right about the still cooking off Xanax. I’m getting fitted for a sleep apnea mouth guard too.

I just can’t imagine injecting daily. That sounds miserable. E3D is bad enough

Melatonin has never helped me long term personally. Lithium orotate 5 mg/day could help with xanax withdrawal. CPAP machine being properly fitted for apnea should help too.

I inject every day. I barely feel it when doing subQ in the glutes with a 5/16" 31 g syringe.

Your total t looks fine I probably would not inject more but would need to see Free T before I say for sure.

Are you taking any supplements or medications? Sometimes those can lower e2.

Okay so I got my test relies back and it’s not better

So I think I have a lack of estrogen problem now. How can I get it raised? Should I go back to SubQ since that’s when o had a higher estrogen problem? Then it was elevated and why it switched to IM.

someone asked above …are you taking any kind of an AI ?

and i agree you need to raise your test amount per week shoot for 180mgs a week

I’m not on an AI.

I fear raising it will kill that estradiol number even more. But at this point I need to make some type of change. My option without adding more medication is go back to SubQ or to your point and/or raise my dosage

fear of raising what will kill your estradiol number even more ?

subq will prob drop it if you keep dose the same as most say absorption rate is slower with sub q

just add more test… your on trt to get the optimal numbers, not mediocre numbers