I take 0.25 mg of anastrozole daily. Once weekly I take 1mg of testosterone cypionate. I’ve been taking test for 13 months, and only within the last month have I started taking the estrogen blocker. With test, i time by blood to be drawn the morning before I give myself an injection. However, I have no idea how to time the anastrozole. Any advice? Also, thanks for any help.
Your taking an AI because?
Doc said the bloodwork showed my estrogen as extremely high. He wanted me on 1mg daily. But, it made me very tired and my joints ached, so downed the dosage until I felt okay. I have blood work coming up in a couple of weeks, and I want to make sure the test results are accurate.
Holy crap. He is hurting you. He made your e2 crash hence your bones aching and tired.
If you are on a trt dose most guys seem to stabilize their e2 after a couple of months without an AI.
I mean if you injecting 1x a week you can take the AI 1x a week. But not more than .5 total a week.
It is wise to take ai only after 6-8 weeks and u have symptoms of high e2 like constant sore nipples AND confirmed high in lab. I tried ai and even .1 mg crashed my e2.
I think your e2 may be low and May need to stop the AI. Need labs.
Some guys like myself rather lower dose of t or increase frequency of injection to lower e2 instead of an AI. Low e2 is dangerous.
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Okay. I’ll adjust down. Best not to take a chance. When I get my labs back in a couple of weeks, I’ll post. Thanks.
That doesn’t make any sense, nobody is prescribed 1mg testosterone cypionate. I think you’re talking about 1ml of testosterone cypionate which doesn’t really tell us how much testosterone you’re injecting. Your vial will have either 10ml 100mg strength or 10ml 200mg strength, so 1ml could be 100mg or 200mg.
Once weekly dosing isn’t optimal considering naturally you produce 7-10mg daily, so once weekly isn’t going to provide excellent results for the majority of men. Your doctor is a fool, 0.25 mg of anastrozole daily!
The majority of endocrinologists and urologists are extremely ignorant in male sex hormones and I’m betting he didn’t test your SHBG levels and that’s because he doesn’t know what he’s doing. Everything this doctor is doing is wrong, lots of red flag here!
SHBG is measured and a TRT protocol is designed around this lab value, it guides injection frequency and this is the correct way to better control estrogen, you should be injecting more frequently so that you don’t need an AI.
If injecting more frequently fails to control estrogen, then a very low dosage AI is needed twice weekly.
The reason why you need so much anastrozole is because of the terrible protocol you doctor has put you on, it’s no wonder you need so much anastrozole. I’m willing to bet your doctor isn’t using the LC/MS/MS E2 labs designed for men, the Roche ECLIA methodology is for women and overstates E2 in men when elevated.
Continue with the anastrozole dosage and osteoporosis is all but guaranteed.
Post all your labs.
Labs from April. Total testosterone 351 ng/dL. Free testosterone 12.0 pg/ml. Total estrogen 145 pg/ml (ref range is 45-115). This was what prompted me to ask about an AI. The doc agreed, and put me on the Arimidex.
Total estrogens is useless and it tells me your doctor is behind.