HCG Not Working After Years of Nebido Rollercoaster

There’s a tough reality that you will unfortunately have to face, and it’s unrelated to you or anything you’ve done. Nebido is not special in any way. It’s just testosterone attached to a long ester. But in order for it to be different (read: patentable by a pharma company) it needed to have something about it that made it different than the very cheap, very available other forms out there. So the dosing protocol is the thing that changes regular testosterone undecanoate into “Nebido”. And that dosing schedule is unbelievably stupid. Nobody with any background in the most basic corner of chemistry or endocrinology would find it to be appropriate. Seriously, here’s what 30 weeks of Nebido on your schedule looks like:

Those huge peaks and troughs are no good. They’re a recipe for feeing like shit. Compare that to Nebido—same drug—used differently:

That’s a 500mg loading dose and then four weeks later you begin 200mg every two weeks. Notice that the peak to trough is less severe and the total change from high to low is a narrower margin. That’s how Nedibo should be used.

If you go back on trt and use the same old drug with the same old protocol expect the same old results.

Now, as far as SERMs are concerned, no they are not like an AI. Different class, different MOA, different results. Read up on them (too much detail for me to explain on my own).

You can use HCG at any time when you’re on trt. I am a firm believer in it because it keeps the testes functioning, albeit at a low level, and that has positive downstream effects that you cannot replicate with testosterone alone.