Guidance on Low T, Obesity, Etc

Please try to get on TRT. Study the stickies. There is one for finding a TRT doc.

Were you fasting for labs?

Fat loss requires good TT, FT, E2, cortisol and thyroid function.

Prostate can have problems with high E2 on TRT or estrogen dominance with low-T. How have prostate symptoms changes with TRT stopped?

What has your history been with PSA and why not tested now.

What meds have you used for arthritis pain. Some Rx or OTC can affect kidneys and increase homocysteine, indicating endothelial side effects.

How much iodized salt? Only your cooking and salt shaker count.

Not taking an statin drugs to lower cholesterol?

Depression can be driven wholly or partly by low T, elevated E2 and estrogen dominance and low thyroid function. Low cortisol could certainly be a factor, but not tested in this lab set.

High BP can also be contributed to by a magnesium deficiency. Leg or foot cramps or the ability to contract a muscle and make it lock up is a sure sign of magnesium deficiency.

Ridges in fingernails and folds in earlobes are associated with increased risk of a cardio vascular event. You should be concerned with endothelial dysfunction, the mechanism of ‘heart disease’. There is a lab test for an inflammatory marker for this" homocysteine". The endothelium is a one cell thick layer that isolates the blood from the arterial wall. Blood pressure is partly a marker of these process. You can protect endothelium with high potency B-complex multi-vits, adequate DHEA levels, fish oils, natural source Vit-E, Vit-C and other antioxidants, good T levels and optimal E2 levels avoiding estrogen dominance. Insulin sensitivity is also important and that also requires optimal thyroid function.

DHEA-S=18 is extremely low, never have seen this. DHEA is made in the adrenal glands pregnenolone–>DHEA. So some concern for other adrenal hormones. Take 25mg DHEA and test DHEA-S again next lab set.

Get AM cortisol blood work, and do this at 8AM or 1 hour after waking up. Please no coffee and try to have a relaxed drive to the lab blood draw station. At doc’s office may involve unreasonable wait times.

Total cholesterol 123 is really too low. Some just are that way as there livers do not produce enough. 180 is optimal and <160 is associated with increased all-cause mortality. Cholesterol is needed for many things including the foundation for making all of your steroid hormones, including Vit-D25, DHEA and cortisol etc.

Vit-D25 would be better if increased please take or increase by 5000iu Vit-D3 per day.

Take DHEA, fish oils, Vit-D3, Vit-E with low fiber meals with more fats. With oatmeal would be the worst.

If taking a statin drug, does seems too high. If so and you have muscle soreness or a persistent low level cough, that is a statin drug induced CoQ10 deficiency.

IGF-1: You may need hGH in the future, check IGF-1 once a year.

TT is low. FT is very low, FSH is strong. Your have primary hypogonadism, your testes are not working well. SHBG is high creating a lot of non-bio-available SHBG+T that reduces FT and free % FT while increasing TT that then over-states your T status that is lower than TT alone implies.

CBC looks very good.

fT3 is slightly low and TSH=2.20 should be closer to 1.0
Thyroid rages are useless and stupid.
Have you not been using iodized salt?

Please post your waking and mid-afternoon “normal” body temperatures.
TSH does not seem right.

#See last paragraph to evaluate overall thyroid function. This is important, more useful than most thyroid lab sets.

You will need to read this post multiple times.
List

Please read the stickies found here: About the T Replacement Category - #2 by KSman

  • advice for new guys - need more info about you
  • things that damage your hormones
  • protocol for injections
  • finding a TRT doc

Evaluate your overall thyroid function by checking oral body temperatures as per the thyroid basics sticky. Thyroid hormone fT3 is what gets the job done and it regulates mitochondrial activity, the source of ATP which is the universal currency of cellular energy. This is part of the body’s temperature control loop. This can get messed up if you are iodine deficient. In many countries, you need to be using iodized salt. Other countries add iodine to dairy or bread.