Don’t know if I should be in TRT or AAS forum - I am cruising on about 180-200 mg T cyp weekly with divided doses . Bringing up dose to 250-300mg weekly for 10 weeks , then back to cruise - been doing cruise for a year with no problems and good results . I have been taking 2mg anastrozole weekly too . I got a few bottles of letro and anastrozole on hand - what dose letro should I try - can I mix AI?
A general guideline for Anastrozole that seems to work for most is 1mg for every 100mg of Testosterone, which is similar to what you are doing for your cruise. So if you up the dose to 300mg/week you could take 3mg/week.
On a side note, I find it very intriguing that guys on TRT have come up with these guidelines through trial and error, usually backed up by lab results, seem to be doing very well with them and yet, their knowledge on this, for the most part, hasn’t passed through to the steroid using crowd who, at the moment, use a very rigid dose of AI (.25-.50mg EOD of Arimidex almost regardless of AAS use) and adjust based almost exclusively on the presence or absence of gyno. I think it would be very interesting to see what happens if a steroid user applies the guideline expressed above with his doses of AAS.
For example 5mg/weeks of Adex on a standard cycle of 500mg Test/week. This is far more than the standard recommendation but maybe it could further reduce some of the oestrogen related side effects that are sometimes deemed inevitable with aromatizable steroids, like water retention, acne, etc.
I have no experience with Letro so I can’t comment much on it but it is very potent and combining it with Anastrozole could prove excessive and harder to adjust. Easier to up the Anastrozole dose and adjust it based on symptoms and lab work. Just my opinion though.
letrozole/femara is much more powerful than anastrozole/arimidex. 0.15-0.25mg EOD works fine as long as you closely monitor your dose and response. the dose/response curve for letro is unpredictable. it does have a long half life but not long enough to take just once a week.
trial and error will have to be your guide. hope you are able to recognize the symptoms of both high estrogen and low estrogen in order to evaluate your dosing. it takes weeks to attain a stable blood level, but should be noticeable once you get there.
my experience has been the leaner you are the less you require. needed higher end dosage when i had higher body fat%.
if you feel libido slipping or have gritty/sandy achy feeling in joints then you have pushed your estradiol levels too low.