Anyone have experience with SLU-PP-322?
If you’re spending time on T Nation, odds are you enjoy exercise. But what if you’re injured, traveling, or having to take care of someone who needs full-time attention?
Something like this might come in handy for a period of time. Here’s what ChatGPT says it does:
What SLU-PP-332 is
SLU-PP-332 is a synthetic small-molecule ERR agonist—often discussed in research contexts as an “exercise mimetic” compound that activates estrogen-related receptors (ERRs), especially ERRα, to drive changes in cellular metabolism and mitochondrial function.
Preclinical Research Findings
Laboratory and animal model studies (primarily in mice) report effects including:
Exercise-mimetic metabolic effects
- Increases in mitochondrial number and function in muscle tissue.
- Promotion of genes and pathways associated with endurance training without actual physical exercise.
Metabolic health improvements
- Improved fat oxidation and energy expenditure.
- Reductions in adiposity, enhanced glucose tolerance, and improved insulin sensitivity in obese mouse models.
Possible tissue-specific effects- Shifting skeletal muscle fiber types toward more oxidative (endurance-type) profiles.
It doesn’t look like it’ll make you jacked, but the metabolic benefits seem promising. What are your thoughts?
This thread is not intended to promote it, but to hear from those who’ve tried it or who have knowledge about it.