Estrogen Sides on TRT - Low Test (323)

Hello!

I hope someone can give me some advice here. I just turned 33, have been exercising (weights) for a year and some months.

Around 8 months ago, I ended a bottle of Erase, as I thought I might have an E problem due to fatigue and lack of ability in the gym even after ~6 months of weight lifting, lack of ability to cut body fat even on very low calories with cardio. I just couldn’t see any improvement. I think it helped some, but then I started feeling tired again.

About 3 months ago I was experiencing extreme fatigue, sleeping up to 14 hours a day sometimes. Taking off work to sleep. That kind of comes and goes, but I’ve felt low energy ever since.

A family member had been diagnosed with low T (300), so I went and had blood work done, including testosterone levels.

Everything came back normal except for the T, which was 323. They prescribed Testim, and I have been using a tube a day for the last 2 months, exactly. I tend to put it on my shoulders, neck and head (shave it), as to prevent my shirt from being glued to me quite as much.

The first 3 weeks I was still tired, but grew a lot of muscle with almost no exercise, then I kind of got back into the groove of working out and got some energy back, but it comes and goes. Now the issue is, I look in the mirror today, and I swear my nipples have doubled in size. They were small, and they still are, but me and my wife see noticeable growth in them.

So, I’m thinking either, I don’t really need Testim and I should get re-tested, or I just convert all my T into E. Which seems more likely? I know only testing will really tell, and I see an Endo in about a week, but I’m concerned about this and would like to know if anyone has any thoughts on it.

Thanks!

Sorry, read the faq, here’s the values :

Name Value Reference Range
Testosterone, Serum 323 348-1197 ng/dL
Free Testosterone(Direct) 5.9 8.7-25.1 pg/mL

Read “Estradiol why you should care” at the top of the home page. It contains everything you want to know. The short answer to your question is that you can easily convert T to E even at a low dose. Some guys on here developed gyno with slight increases in their testosterone. I personally developed gyno and had great results with Raloxifene.

Here is my original post from last year.

“Hey Guys, I have been on TRT for over a year. I gradually worked up to a max dose of 10 grams/Androgel a day. Somewhere between 7.5 grams and 10 grams I had a very rapidly forming case of gyno. I immediately lowered my dose to 5 grams until I could see my Endo. I previously had pubertal gyno that resolved itself and a surgical case of gyno about 4 years ago which I had removed. No AAS or Prohomones just super sensitive to hormonal changes. Anyways my doctor prescribed Raloxifene 60mg/ED about a month and a half ago and my nipple puffiness has subsided greatly. The swelling around my nipple has gone down as well but I still have tenderness and a deeper lump below my left nipple. It has subsided to the point where I don’t notice it in the mirror. Not sure if this is a success story just yet but I am quite happy with the results so far. I have now switched to shots but at a really reduced dose of 50mg/week. Considering the low dose I feel pretty good.”

I have read the estradiol post and think it is likely to be what’s happening. Is it possible that’s why I had low T in the first place?

I saw my Endo, she basically said since I am on Testim that any tests would be invalid. So, I need to go off Testim for 2 months and then go in for blood work. I don’t really agree with that and since my HRA account is out for the year, I pushed the blood work out to January.

This gives me another month or so on Testim, which I plan to take Erase with to see if that negates any of these side effects. Anyone have an opinion on this idea?


As kind of back story, I have been diagnosed with IBS, OCD, and anxiety. The way the medical community sees it, is OCD, IBS, stress, low T are all caused by anxiety. I see it a bit differently, when you worry about shitting yourself on a daily basis, that is going to make you anxious, overly cautious of those situations and cause you a lot of damn stress. The endo said I need to be seeing a psych and therapist (which I do, to no real avail at this point) and that my low T is probably caused by anxiety.

The reason I mention all this, is because before I was diagnosed with low T, but I had a good indication I had it due to my brother’s similar symptoms and blood work, I took dermacrine and erase. Interestingly, the IBS seemed to improve markedly. My completely unsupported theory is that an imbalance of estrogen/estradiol/testosterone and negatively affect digestion. So, this is why I am planning on Testim and Erase for a month, just to see what that looks like, in terms of these other issues I am dealing with.

Any input, feedback, opinions… positive or negative are appreciated. Any anecdotal experience or studies would also be much appreciated. I have used google scholar quite a bit, and been through NIH and pubmed, but I am well aware that I can’t understand it all nor find it all.

Thank you for your patience and help!!!

You would need your blood tested when you are on your protocol in order to see where your T and E are at. My anxiety was caused by the Low T. I’d rather treat the problem than the symptom.

So, perhaps I should just get independent blood work?

Did anyone test prolactin prior to trt?

When you say everything is normal that means nothing to us. Please post your labs so we can better assist you

What about thyroid labs??

Cholesterol

Ast,alt

Cortisol?

List everything please

I hope this makes sense to you folks!

Thanks!

Hey mate,

I took propecia and over night I got low t. I have all the problems u are talking about. Digestion, anxiety, all of that. I did not have it before low T. Now I have it constantly. And taking anti estrogens does help.

Do you have an estradiol result? LH FSH?

Your Platelets 149 are low just like mine.

You must feel like shit? How is your libido and energy?