Estrodial Levels: At Odds with TRT Doc

Pharma TRT
1

I pin MWF at 50mg T (total 150mg T weekly) and it gets my Free and Total T at optimal levels, and take Anastrozole at 1.5mg/week in equal doses. My E2 levels went from 50 to 21.

However, doc now wants my levels ‘above 30’ and that I should cut back on the AI. They cite optimum heart health for men requires above 30.

I think it’s fair to say that the stickies on this forum and Life Extension disagree with that advice.

Looking at this article from Life Extension

they recognize a conflicting study, which must be the study my doc is basing his E2 view on. “This study nonetheless was used at the anti-aging conference to proclaim that estradiol protects against heart attack.46”

What do you guys think, is my doc basing his protocols too much on 1 study? Have some of you guys gone over 30 and felt like crap? I really don’t feel any different at 50 v. 21 to be honest.

I think long term I’m going to be fighting with my doc to let me keep my E2 levels in the 20-30 range as they will cut back on my Anastrozole script to get my E2 levels down. I have Liquidex as well so I can self-supplement.

2

Honestly, the number will be different for everybody. Some guys will feel better at the magic 22, while others may feel better at 32. 10 points likely won’t make a difference, especially if you don’t feel any different. If you have a good doc, is it worth the fight?

3

I’m going to bet that you can remain under 30 with 0.5mg anastrozole E3D versus the 1.5mg/wk you’re currently on. I saw a research study that compared two groups of men on TRT with one taking 1mg every day and the other taking 1mg only twice a week. The E2 was virtually the same and TT was only slightly higher in the 1mg every day group.

As for the E2 level, I think your doc may just be concerned that you may dip below the lab test’s range of accuracy. Mine recently went below 27 which is the lowest the test can measure. It could be zero for all I know. I’m cutting back to 0.25mg E3D

4

If you are at the top of the range for Free T, E2 around 30 probably won’t hurt.