Estradiol: Why You Should Care

Human menopausal gonadatropin hormone I think. May be a mispelled but that’s close.

my E2 is staying at 28…would getting it lower make that big differnce ? TEST was 750 up from 177

[quote]fightu35 wrote:
my E2 is staying at 28…would getting it lower make that big differnce ? TEST was 750 up from 177[/quote]

Is that what is was before? How much Test dosage and duration been on it? Gel or injection? Any AI taken? Any ED issues resolved?

I just got an Estradiol “Ultra Sensitive” instead of the standard E2 test.
The test result says Estradiol LC/MS/MS and the number was 13pg/mL in a range of < or = 29.
Something is up.
A. Because they ran the wrong test
B. If my E2 was really that low, I’d have achy joints from hell, wouldn’t I?
I need the standard test done; the E2 test with a range of 0-54, so I know how to compare apples to apples, not apples to kumquats.
Oh well, I’ll have them do the right one next time…

[quote]KNB wrote:
I just got an Estradiol “Ultra Sensitive” instead of the standard E2 test.
The test result says Estradiol LC/MS/MS and the number was 13pg/mL in a range of < or = 29.
Something is up.
A. Because they ran the wrong test
B. If my E2 was really that low, I’d have achy joints from hell, wouldn’t I?
I need the standard test done; the E2 test with a range of 0-54, so I know how to compare apples to apples, not apples to kumquats.
Oh well, I’ll have them do the right one next time…
[/quote]

There are those numbers that I said would be unfamiliar. You may need to read them in the context of the different range.

Perhaps your level is 13 * 54/29 = 24.2 in the old range. Or is this totally wrong?

Go by how you feel. You do not feel like you thought the numbers implied??? Got libido?

Does this mean that the Labcorp serum E2 test is always inaccurate and reading high?

They did do the right test…

http://www.questdiagnostics.com/hcp/intguide/EndoMetab/EndoManual_AtoZ_PDFs/Estradiol_Ultra_Sensitive.pdf

The ultra sensitive test is intended to be used with prepubescent children and post menopausal women [<10] were E2 levels are very low.

Labcorp: “Estradiol results obtained with different assay methods cannot be used interchangeably in serial testing. To monitor a patient’s serial results, it is best to ensure that the same methodology is used each time the test is performed.”

Why do the basic serum labs and this one have different range units? What is considered an optimal E2 levels when using this test?

I do not know. Tower of babel.

Same problem occurs when you do saliva or urine based tests… different numbers, what does that mean?

KSman,
Thank you for clearing this up. I was hoping you would help. Still have libido and morning wood and I don’t feel “puffy”, so I won’t worry about the ranges of this new test. I am currently on 11 drops a day of liquid adex, and actually feel pretty good. When I had dropped back to 1mg/week my E2 was up to 69 and I knew something was up, and I needed it to be verified…

Also, I have been taking finesteride 1mg/day for hair loss and thought to get my DHT checked. Test result was 20 out of 25-75ng/dl. That tells me it’s time to cut my dosage in half. I don’t know what the “optimum” number is for DHT. KSman, once again, any suggestions?
Thank you in advance.

[quote]TrueDude1965 wrote:
fightu35 wrote:
my E2 is staying at 28…would getting it lower make that big differnce ? TEST was 750 up from 177

Is that what is was before? How much Test dosage and duration been on it? Gel or injection? Any AI taken? Any ED issues resolved?[/quote]

never had it checked before TEST…Ive been on test for about 3-4 months…its staying at 28…
test enanthate 100 a week

[quote]GaryCDeWitt wrote:
My urologist says he has seen cases before where total T was low, but free T was in the normal range.

[/quote]
Total T 473
Free T 129 (normal is 35 - 155)

I’m one of those cases. Still felt like crap, mood swings, lack of morning wood and finally started taking anastrazole. Mood swings went right away, still working on the morning wood.

The first shot I would wake up and have to walk around with a pillow for a bit but by the next week it was gone, literally. So I probaly just need to increase my dose. Energy lvl’s though are pretty low in the afternoons, could be lack of sleep.

I’m seeing the Dr. Monday to try to get him to give me some Hcg and talk about the lack of energy issues, wondering if that might be from estrogen also.

[quote]Rapt wrote:
GaryCDeWitt wrote:
My urologist says he has seen cases before where total T was low, but free T was in the normal range.

Total T 473
Free T 129 (normal is 35 - 155)

I’m one of those cases. Still felt like crap, mood swings, lack of morning wood and finally started taking anastrazole. Mood swings went right away, still working on the morning wood.

The first shot I would wake up and have to walk around with a pillow for a bit but by the next week it was gone, literally. So I probaly just need to increase my dose. Energy lvl’s though are pretty low in the afternoons, could be lack of sleep.

I’m seeing the Dr. Monday to try to get him to give me some Hcg and talk about the lack of energy issues, wondering if that might be from estrogen also.

[/quote]

can I ask how much test you are taking ? and the adex helped that much ? how long did it take… ? if morning wood is any indication…then im junk…i never get it…lol

100mg x 1wk test
8 drops eod adex
mood swings was pretty quick I only started adex 1.5 wks ago

thank you

Hey guys,
I hate to cross into the “graphic” question category, but since we’re talking about Estrogen and it’s related issues, here goes…
I remember when I was younger I could “hold” a climax for what seemed like forever, and then as I got older I could delay it a bit, but not really “control” it. I have since found out if my E2 levels start to creep up (somewhere over 30+) my control is much less, but if my E2 is down in the good zone, I can do what I did when I was 19 again. Is there anybody else that has noticed anything similar to what I describe?
If you don’t want to discuss it in open forum PM me if you would with a: yes, no, or a related story.

I figure if I tell what’s happening to me related to my HRT/TRT and it’s “side effects” in open forum, maybe, just maybe, a new guy like I once was will read something and realize he’s not alone. Or maybe his wife will read something we have written and have a “light bulb” moment.

The main reason I decided to start on HRT was after lurking around T-Nation for a few months (2-1/2 years ago)and reading things I would have never had the guts to ask my female doctor(back then)about I decided to take the plunge, and after getting dialed in, finally life is now and potentially will be for years not only bearable, but quite interesting and productive in spite of my getting older.

Funny you say that because I had the same issue on 200mg a week without an AI. I thought I was over stimulated from the T but maybe it was high E2. I know my E2 had to be way out of range then.

have you guys read & found as much info as I have about not needing any AI’S under 1 gram a week…some are affected some not…I know someone on 200mg TEST a Week with no other drugs and maintains a decent estrogen level 25 (<16-20 normal)unless im wrong…would getting that # lower realy make a difference ? any cases like this here ,would be great,and some scores and results with newer lower #'s

I’m still trying to find that perfect spot with my e lvls but as of now I’d say no. Of course I have the wife always saying, “Are you done yet?”
On another note, are headaches a sign that I’ve went to low on E?

What are the signs/symptoms of low E?
thanks

[quote]fightu35 wrote:
have you guys read & found as much info as I have about not needing any AI’S under 1 gram a week…some are affected some not…I know someone on 200mg TEST a Week with no other drugs and maintains a decent estrogen level 25 (<16-20 normal)unless im wrong…would getting that # lower realy make a difference ?

any cases like this here ,would be great,and some scores and results with newer lower #'s[/quote]

Have you been on HRT/TRT for 2-1/2 years or more like the rest of us? SOME guys NEED an AI on 200mg’s a week, and SOME DON’T.

Until I started on HCG, my E2 level was manageable but not optimal. I like erections that last 25 minutes instead of 8 or 9 and without an AI, 8 or 9 would be a good day.
Look, I have spent at least 2000 hours over the course of the last 2-1/2 years doing research on HRT/TRT and it’s side effects.

You’re kinda new here, and I doubt you have had the time to read EVERY post on HRT and AI’s and the related stuff in the Steroid section as well.

Please, If you don’t have first hand knowledge about someone’s health by knowing yourself, please don’t confuse the new guys that aren’t clued in yet, okay? AI’s are a wife saver for a lot of us. Yes, I said wife…

[quote]KNB wrote:
fightu35 wrote:
have you guys read & found as much info as I have about not needing any AI’S under 1 gram a week…some are affected some not…I know someone on 200mg TEST a Week with no other drugs and maintains a decent estrogen level 25 (<16-20 normal)unless im wrong…would getting that # lower realy make a difference ? any cases like this here ,would be great,and some scores and results with newer lower #'s

Have you been on HRT/TRT for 2-1/2 years or more like the rest of us? SOME guys NEED an AI on 200mg’s a week, and SOME DON’T.
Until I started on HCG, my E2 level was manageable but not optimal.

I like erections that last 25 minutes instead of 8 or 9 and without an AI, 8 or 9 would be a good day.

Look, I have spent at least 2000 hours over the course of the last 2-1/2 years doing research on HRT/TRT and it’s side effects.

You’re kinda new here, and I doubt you have had the time to read EVERY post on HRT and AI’s and the related stuff in the Steroid section as well.

Please, If you don’t have first hand knowledge about someone’s health by knowing yourself, please don’t confuse the new guys that aren’t clued in yet, okay? AI’s are a wife saver for a lot of us. Yes, I said wife…

[/quote]

Most of my reading has come from off here also…and trust me I have read many many many posts here…but no one realy seems to ever show they was once was say 28 ,then dropped to 15 and was great…

and are you saying you never ‘heard’ nor read that some will never need it…and alot under 1 gram of Test will not…maybe I need some new books…so now …any input ?
yes…no…maybe so…about the post ??
thanks for the reply.

also …my post was a ?, never any suggesting to anyone new…im new myself…thats why im here…

[quote]fightu35 wrote:
KNB wrote:
fightu35 wrote:
have you guys read & found as much info as I have about not needing any AI’S under 1 gram a week…some are affected some not…I know someone on 200mg TEST a Week with no other drugs and maintains a decent estrogen level 25 (<16-20 normal)unless im wrong…would getting that # lower realy make a difference ? any cases like this here ,would be great,and some scores and results with newer lower #'s

Have you been on HRT/TRT for 2-1/2 years or more like the rest of us? SOME guys NEED an AI on 200mg’s a week, and SOME DON’T.
Until I started on HCG, my E2 level was manageable but not optimal.

I like erections that last 25 minutes instead of 8 or 9 and without an AI, 8 or 9 would be a good day.

Look, I have spent at least 2000 hours over the course of the last 2-1/2 years doing research on HRT/TRT and it’s side effects.

You’re kinda new here, and I doubt you have had the time to read EVERY post on HRT and AI’s and the related stuff in the Steroid section as well.

Please, If you don’t have first hand knowledge about someone’s health by knowing yourself, please don’t confuse the new guys that aren’t clued in yet, okay? AI’s are a wife saver for a lot of us. Yes, I said wife…

Most of my reading has come from off here also…and trust me I have read many many many posts here…but no one realy seems to ever show they was once was say 28 ,then dropped to 15 and was great…

and are you saying you never ‘heard’ nor read that some will never need it…and alot under 1 gram of Test will not…maybe I need some new books…so now …any input ?
yes…no…maybe so…about the post ??
thanks for the reply.

also …my post was a ?, never any suggesting to anyone new…im new myself…thats why im here…[/quote]

I apologize for attacking you, I’m having a tough week…
Yes, I have heard some guys even at a gram a week don’t need an AI. My point albeit sloppy was, is there are a lot of new guys cruising through these posts looking for help for their hormone imbalances. What if your post was the only one they paid attention to, and it said no AI’s are needed for some guys?
I have had many experiences with guys that missed the point of a post, went off the deep end, and then had to crawl back to normal by whatever means possible after going through hell.
I may be wrong here, but I so often get emails about E2 related issues from guys with “bad” doctors I would rather be safe than sorry. Look, if you buy some liquidex and it doesn’t help your situation after a month or so you’re out $70.00, and know to look elsewhere to fix the problem. But, if you think “maybe” I’m a guy that doesn’t need an AI, and you are, you get “welcome to hell” instead of a better quality of life.
That’s what I actually meant.

KNB keep in mind…I am here to learn…I can not learn unless I ask…I have read many posts from you…and you are very smart…Ksman has helped greatly as well,and others…Im trying to figure this ANTI thing also.so let me tell you a lil about my case…been on enanthate for about 5 months…dr.wanted 200mg’s every other week…I do 100 every week…(might go to 200)…I do not feel any big changes I get huge pumps now yes…im a lil stronger…

I have no idea what my estrogen was before…but it was 28 at last check…and my doc say I prob will be on TEST for life…but says I do not need anti’nor HCG…thats the ? OF differnt stories with anti’s
*i do not take anything else…never have.any input ,I thank you.

and thank you for the sorry…not needed…you earned ya right…lol you help many here