E2 Not Responding to Arimidex, Aromasin

not t2d but they go into the detail on how the scientific studies are manipulated. even the gold standart mendelian seem to be influenced and skewed
and the tldr is on ldl here is the optimal longevity level is 140-160ng/dl. triglycerides matter and hdl as well, but it mostly a matter of metabolic health

There has to be some sort of justification if you are gona have people be a pin cushion. If it’s about “what works for me” at least say that and nothing else.

Atleast the person then knows it’s nothing backed up by anything other than anecdote and there is nothing wrong with them if they don’t like pinning ED/EOD. Nor do they have to keep trying over and over to pin so frequently if it’s not the ultimate answer.

Not to mention ED/EOD injection of test cyp did NOT work for you either. So you didn’t only not respond well to biweekly injections.

I’m actually relieved to hear that - because last week I also asked my Endo if he could do a therapeutic phlebotomy as well. I still didn’t hear back from him. But my endo is not an asshole, so I doubt he’ll give me the usual “red-tape” bullshit excuse.

Some say 200/mL/week is too high a dose, some say it’s too low a dose. I tried higher doses in the past - I cannot handle those at all.

Also - Just so you know - I’m not taking any Anabolic Androgenic stuff besides what I said.

Me too! (I thought I was the only one!)

Mattys,
What brand name of HcG do you take?

SystemLord,

Since you have more experience - My father and myself both carry a genetic mutation called C677T Homozygous MTHFR. My dad’s “holistic” doctor did the test for this and got the results first. When my dad brought these results to his Mainstream Allopathic physician, the guy wanted to put my dad on Coumadin (blood thinner). My grandpa was on Coumadin before and reported nasty side effects - so my dad refused any blood thinners.

Have you ever heard of this mutation (MTHFR)  causing "thicker blood"?

Whoever is telling you 200 mg/week is too low of a dose for actual TRT, you stop probably listening to them.

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Are you accusing me of lying? Are you accusing me of being on AAS steroids?

@Meathead56 is right, your levels are well outside the normal ranges, so not a TRT. TRT is about replacing what you would have naturally, so <916 ng/dL.

A Total T at 2798 ng/dL and a Free T that’s almost 6 times the normal limit, not normal, meaning this is unnatural, therefore it’s a cycle or performance enhancement therapy.

To be clear, no one is judging you, but this isn’t TRT.

I know nothing about this gene mutation, but I have ADHD and Tourette’s syndrome.

Can low thyroid hormones cause such an excessive response to TRT? I do know thyroid is responsible for timely elimination of other hormones such as cortisol.

SystemLord - you were still quite correct when you suggested (from your own experience) that injecting T-Cyp SubQ can be more risky than the traditional, long-used route of intramuscular. I personally believe that also plays a role in my labs showing such excessive hormone levels. From now on, I’ve ditched the SubQ route for T-Cyp.

SystemLord,
You may call me “paranoid” if you wish - but I believe that these online TRT forums are full of “disinformation”-spreaders. Why? Because they clearly don’t want most men to know how to safely use testosterone. They don’t want men to be too ‘assertive’. That’s also why they put EDC’s (like Xenoestrogens) into our food which makes us fat.

I’m laughing not knowing if you are serious with this. You are on steroids. You said so yourself.

You deleted a question to me. I’m on testosterone (plus other anabolics) and take 200-400mg per week non-stop. I was diagnosed with hypogonadism (was low T for a decade before starting T), but I’m not on TRT. I’m cruising on a low dose steroid cycle indefinitely.

I didn’t start with a kitchen sink approach with multiple drugs at the same time. You’ll never know what is causing you issues with that approach. I’ve posted about everything I’m taking many times.

Good luck getting everything figured out.

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Low thyroid hormone would be a reason for a non response to TRT, testosterone is metabolized in the liver and thyroid hormones are needed for that to occur.

Had you originally tried high normal hormone levels in the beginning and having it not produce a strong response to therapy, then tried bumping the dosage a little higher or titrating the dosage higher until you get a robust response.

EDC’s or not, you didn’t even attempt to use the minimum effective dosage to relieve your symptoms and now are trying to justify running extremely high levels, blaming EDC’s when it’s not proven to be your issue.

Claiming they don’t want us men to be assertive, is another attempt to justify running these very high levels. As far as being assertive, more masculine, these are traits not every man will possess as strongly as the next man.

I’ve seen some mentally weak men with high testosterone, pussies! Testosterone isn’t automatically going to make you the man you want to be, easpecially if you don’t already posses these traits.

Systemlord,
So you think 200/week is too much for me? Fine. What dosage would you recommend?
I started TRT because I felt like I was getting too sedentary, and not exercising nearly enough. My blood labs were also showing very low T levels. I always knew TRT was a “risk”. But nobody gets results if they fear taking risks.
But then, after a year on TRT, still not getting the results I wanted - I realized I’m taking a beta blocker (which can cause chest pain, heat intolerance, shortness of breath from walking up stairs). I was placed on this Beta blocker in 2006, because I was complaining of chest pains which were related to SSRI-Antidepressant withdrawal symptoms. This 2006 SSRI withdrawal “syndrome” has virtually damaged my entire central nervous system. It totally shortens my attention span and reading comprehension ability. For 2 straight years it felt like having grand-mal seizures 24 hours per day - until 2008 when my doc finally placed me on something that “managed” these symptoms well enough - Klonopin. Despite Klonopin, the damage to my nervous system by the 2006 SSRI syndrome was done. I must’ve done something very bad in a past life to be punished so severely in this life.
Systemlord, I may sound incoherent to you, or I may sound like I’m not “following your directions”… but I truly struggle just to stay alive every day. If I wear your patience out, I’m truly sorry. I’m trying my absolute hardest.

80 mg per week. I got great levels at 75 mg weekly, high normal at peak and a respectable 490 trough.

I’m on a beta blocker and Clonazepam withdrawal is what f*** me up. I never recovered from protracted withdrawal.

I never had ED or libido issues on Clonazepam, which was treating my diabetic hypertension, only thing is I didn’t find out I had type 2 diabetes until I came off clonazepam.

It can take several years to recover from 30 years on benzos.

Trust me, it’s not the beta blocking causing these symptoms.

People with diabetes, our bodies don’t function very efficiently and cranking up your hormones can make things worse.

Systemlord,
This is why I like talking to you. We’re both coming from the same point of health issues. I think you are the LEAST likely to lie to me on these TRT forums.
I can understand that frustrated tone in your words. I never take your frustration personally because I know exactly how angering it feels to have these mutual health issues (Diabetes, protracted drug withdrawal). I’m so sorry that you have to deal with such brutal health issues - but I’m very happy to have the opportunity to communicate with you.
I hope that feeling is mutual. And I really hope that I’m not a burden to speak to.