You just never know, hormonal shifts can cause massive disturbances in previously well-balanced individuals. I know multiple therapists/doctors who’ve told me that their female patients experience horrific symptoms around menstruation, granted most have pre-existing mental illness.
Withdrawing from TRT was the worse (BY FAR) experience of my life and took me down a mental path I never thought was possible for me, still haven’t fully recovered. Not comparing going cold-turkey off a hormone to coming off an AI, but we’re all bio-chemically unique and react differently to things. Just saying, anything is possible, especially if he was already stressed.