Yup, just waiting for a call back from the doc’s office re: Arimidex.
I’m just a little miffed that the E2 result came back a week ago, and I still don’t have the script. I’ve been feeling like feces warmed over for the last month or so.
With luck, maybe this general feeling of shit on top of shit will go away.
Very possibly. High estrogen absolutely can make one feel bad. Getting it to a good level will make a big difference for you I think.
Update, took home a bottle of orally dosed anastrozole today, insurance covered it, so only $10… pharmacist was surprised, she said she’s never seen it prescribed to a male before.
So my doctor conferred with an endo, after all that, dose is 1mg a day.
Alright, new blood work, time for an update.
Since my last posting I’ve been taking anastrozole at 1mg daily based on doctor’s order.
Ok, first, the bloodwork:
Total T: 613 ng/dL Lab no longer offers a reference range, it used to be 300-1100
Free T: 33.1 pg/mL , ref range of 4.3- 30.4
E2: <2 pg/ml, reference range of < OR = 29
So, in about 32 doses of anastrozole at 1mg a dose, we crashed out my E2.
Ok, so with these data above, I have a question.
Think my next injection, which is friday, I should increase the amount from 200mg to 300mg, to try to get the E2 up a bit, paired with bringing the anastrozole dose down to 0.25mg ED?
Is 0.25mg ED still too aggressive? Sore joints are starting to pop up, so it’s not long before life is the suck again.
Another thought was, take this next T dose at 300mg, then do a 100mg bump next week, and lay off the AI until my next full 200mg dose, which would be on June 12 or so. So:
5/29: 300mg
6/5: 100mg
6/12: 200mg
6/26: 200mg
This is assuming I continue my normal schedule of 200mg E2W. I’m sending a request to my doctor to increase dose, and change dosing frequency to EW.
[quote]dbmata wrote:
Alright, new blood work, time for an update.
Since my last posting I’ve been taking anastrozole at 1mg daily based on doctor’s order.
E2: <2 pg/ml, reference range of < OR = 29
So, in about 32 doses of anastrozole at 1mg a dose, we crashed out my E2.
[/quote]
1 mg per day is the female cancer dose, not the usual dose for male TRT. A more usual male starting dose for anastrozole is 1 mg per WEEK in divided doses, and then only if the patient cannot reduce E2 first by (1) injecting more often, and/or THEN (after allowing 4 weeks to stabilize) (2) lowering the T dose if blood levels of E2 still require it and T levels allow (which you will only know after having been on more frequent injections for a month and then testing T and E2 levels). In that order (in your case). To repeat, that would be the starting dose subject to adjustment, but only if the above two changes have failed. If you are able to control E2 with adapting frequency of injection first and then possibly adapting T dose, that is superior to adding anastrozole, which comes with its own host of problems for many people, as any casual perusing of this and other TRT sites will show.
[quote]seekonk wrote:
1 mg per day is the female cancer dose, not the usual dose for male TRT.[/quote]
Correct. It’s also the dose my physician gave me. As you see from the data, it “worked”.
We’ll see. I have a request in to my doc for him to rubber stamp a change in dose to 125mg EW. I’ve also asked him what to do about the AI dose.
Yup, I’m not comfortable with dosing the anastrozole for the duration of my trt. All dosing is currently subject to adjustment. Considering how low my total t is right now, I don’t think adjusting my T dose down is going to happen. I might agree if it was 1100, but not at 600. Would changing dosing from once every 2 weeks to once weekly or even twice weekly have much of an impact on aromitization?
[quote]dbmata wrote:
Would changing dosing from once every 2 weeks to once weekly or even twice weekly have much of an impact on aromitization?[/quote]
Anything can happen, but normally, yes, it would.
[quote]seekonk wrote:
[quote]dbmata wrote:
Would changing dosing from once every 2 weeks to once weekly or even twice weekly have much of an impact on aromitization?[/quote]
Anything can happen, but normally, yes, it would.
[/quote]
I’ll push for that.
Recently saw a new doc about suspected thyroid issues, and she offered to take on the trt. So there might be that option if there isn’t an agreement for lower doses more frequently.
bleh, tired of feeling crummy, trt was supposed to help me feel a little better. >_<
Just curious, but would taking:
BPC 157
Peg-MGF
Mod-GRF / GHRPS2
Impact aromitization, or Total T value? I’ve got some muscle and knee issues I’m using the above to help speed healing and rehab on.
So, as of today, fully off script with my doc.
Changed from 200mg E2W to 100mg weekly, split into two doses, Tuesday and Friday. He likes testing me on Wednesdays, so I’d just hold off on the Tuesday injection, and do it after the blood draw on Weds.
So, interesting morning.
My doc messaged me saying that this has gotten more technical than he is comfortable with, and suggests that I meet with an endo.
This was in response to a request to change my Test-c dose to 125mg wk (which I’d split into two doses), and asking what he wanted to do with the anastrozole for long term management.
So. That’s something.
Just a quick little update. My new doctor has taken over. She’s a naturopath.
I’m currently injecting 2x a week, 50mg of test-c per dose for 100-120mg a week.
I’m on anastrozole 0.25mg every other day. Things are moving along fine. New doctor wants to do saliva testing, but I’ve told her that if I am to get a TUE from USAW, I need to have an unbroken history of bloods for them to look at.
There is a new wrinkle, which is something we’re going to hunt up. My TSH is up over 4, my T3 is within normal range, but my T4 is below lab range. I’m waiting for the precise numbers, which I’ll put up, but I wonder if this is one reason why I can cut until I’m a physical mess, but don’t lose any of the weight.
How are you feeling on the new protocol?
Odd, my response to you from yesterday didn’t post.
I’m feeling good on the new protocol. The once a week doses I’d have a peak and trough feeling, now I’m fairly level. Also taking 0.25mg of anastrozole EOD has my e2 levels in check.
There are a few other things I need to deal with but as far as this goes, it’s going well. I just wish I could put on a little more muscle. lol.