Dbossa, Interviews About AIs?

Impressive his point of view, clarifixes some things about the failure of my trt 5 years ago.
TT 1500
TFree 29
E2 32
Shbg 23
Dht 266

I felt so bad about TRT that I gave up. After that I gained weight and developed lipomastia, very low energy,it takes me 4 days or more to recover after training. I feel like an old man, and I’m 39 years old.
Below my last laboratory exams.

TT 306
E2 29
Shbg 15
Dht 248

Now I decided to try again, dr started with nebido (every 8 weeks) and 250mg durateston (10 in 10 days). Supplements 2g Tribulus, 1g Mucuna, 1g maca, 5mg tadalafil, saw palmeto 600mg. Could any of these supplements decrease estrogen?

Composition of Durateston
Testosterone propionate: 30 mg.
Testosterone fempropionate: 60 mg.
Testosterone isocaproate: 60 mg.
Testosterone decanoate: 100 mg.

Sorry for my English, I’m Brazilian.

@gus.imoveis
Dude that’s not an ideal TRT protocol. Cypionate or Enanthate twice weekly has a solid reputation for working. Injecting every 2 months alongside a bunch of unneeded supplements that will likely do more to make you feel like crap than make you feel good and is about as far from ideal as you could get.

I get that Nebido & Durateston may be all you have access to (although I seriously doubt it) you can inject smaller amounts more frequently and (while still not ideal) likely get better results. If I were you I’d find a way to get Cypionate or Enanthate but regardless I would ditch those additional supplements especially during the first 6 months.

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That looks a lot like Sustanon/Omnadren. Probably only needs that shot once every ten days and nothing else. It’d meant to do the same thing as frequent shots without doing the frequent shots, but YMMV if you know what I mean.

Really Durateston = Sustanon.
Are there successful protocols using Sustanon?

Thanks for the answer. Cypionate is also easy to find here. What would be the ideal protocol, how many mg / week?

From what I understand from the posts of @dbossa, the ideal would be to have the total testosterone 15 to 25x higher than E2, correct? Is there any parameter considered ideal for shbg, dht, tf, prolactin, for those who do trt?

One shot every 10 days or once every 2 weeks seems to be the norm. I liked sustanon, but cypionate is a lot cheaper and easier to dial in.

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Sorry I’m late to this thread but was wondering how you got gyno with low E2 and how did you know you had low E2 when you got it. I ask because I got gyno in puberty and then accumulated fat in the area over the years as I got older. I have to stay fairly lean all the time so it doesn’t show. Eventually will just get the surgery,

@Gus.Brazil
I would start at 150mg/week cypionate total split into 2 shots (75/mg every 3.5 days). Do that for 8 weeks and then report back how you feel. Don’t worry about any of the other stuff

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Not even with DHT and hair loss?
I have lipomastia, so I worried about dht, e2, prolactin … My prolactin is at the upper limit.
I have Durateston (Sustanon) and fog for 6 months yet, because I started TRT on 03/23/20.

I had gyno way before TRT (twice actually) and never experienced any gyno while on. Even with an E2 level of 80. I spent the whole first year on TRT obsessed with estrogen levels and preventing gyno. It was miserable. Turns out it was a total waste and high estrogen doesn’t automatically mean gyno even in those predisposed to it.

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I’d agree. 150mg/week of test E or C, split it to 2-3 injections and give it a few months. Nothing else.

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My understanding from last couple years (TRT 4 years). Isn’t the reason high E2 is bad because it blocks T receptors in the cell. If they are blocked, T is not going to do what it should? You say E2 should rise with T but Exogenous and Endogenous T work differently in the body I thought. That’s why people who are on exogenous T need an AI? I didn’t hear any science relating to T and E receptors in the youtube vid, not much science just anecdotes. I take 37.5mg twice a week, I’m 5’8, 68 kg. My T is 25nmol ([11-40] nmol/L) on the morning of a trough day. I was taking 0.2mg if AI on an injection day, my Estradiol was 150[55-165] pmol/L. I’ve increased that to .33mg on a injection day, hoping to get it done to 80’s. When my T was 43 and E2 was 180[55-165] pmol/L my ankles swelled badly, and I almost cried when I saw something sad on TV, also moody, snappy. I’ve had had low E2(<40) and high E2 (186) I know the feeling of both. I think between 70-100 most guys will be fine. There is no way I want to inject EOD or daily just to stop taking an AI.

Don’t post lab ranges. That way no one has any clue what you’re talking about.

Enlighten us on the science you base your thinking on. I didn’t hear any science in your post just someone taking something without stating why they need it. Some anecdotal reasoning based on feeling even though they didn’t state how they felt. So basically you said absolutely nothing.

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No. Just no.

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b-b-b-broooo science

Lab ranges added to post. These were just my observations from my TRT. I was just repeating what a Doctor has told me, I know doctors can be wrong. I’m hear to learn and if I missed something that changed in the last couple years I’d like to know. I just wanted that youtube video to offer a bit more. The title suggested it will convince me I don’t need an AI.

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Yes, cells do have E2 receptors…but they are different that those androgen receptors Test binds to.